Endo-1,4-beta-xylanase z-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

endo-1,4-beta-xylanase z precursor-like protein

Species:

Leishmania braziliensis

UniProt:

E9AIG6_LEIBR

TriTrypDb:

LbrM.20.5330 , LBRM2903_200068000

Length:

209

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AIG6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AIG6

Function

Biological processes
Term	Name	Level	Count
GO:0008152	metabolic process	1	2

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	2
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	4	2
GO:0016787	hydrolase activity	2	2
GO:0016798	hydrolase activity, acting on glycosyl bonds	3	2
GO:0031176	endo-1,4-beta-xylanase activity	6	2
GO:0097599	xylanase activity	5	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	86	90	PF00656	0.712
CLV_NRD_NRD_1	198	200	PF00675	0.647
CLV_PCSK_KEX2_1	198	200	PF00082	0.647
CLV_PCSK_SKI1_1	179	183	PF00082	0.654
DEG_Nend_UBRbox_3	1	3	PF02207	0.716
DOC_MAPK_MEF2A_6	42	49	PF00069	0.607
DOC_MAPK_MEF2A_6	73	80	PF00069	0.601
LIG_14-3-3_CanoR_1	139	148	PF00244	0.617
LIG_14-3-3_CanoR_1	159	163	PF00244	0.364
LIG_eIF4E_1	44	50	PF01652	0.593
LIG_FHA_1	130	136	PF00498	0.601
LIG_FHA_1	21	27	PF00498	0.542
LIG_FHA_1	73	79	PF00498	0.604
LIG_FHA_2	116	122	PF00498	0.619
LIG_FHA_2	141	147	PF00498	0.627
LIG_FHA_2	165	171	PF00498	0.704
LIG_FHA_2	20	26	PF00498	0.548
LIG_FHA_2	84	90	PF00498	0.689
LIG_Integrin_RGD_1	87	89	PF01839	0.716
LIG_LIR_Apic_2	33	37	PF02991	0.650
LIG_LIR_Gen_1	132	140	PF02991	0.596
LIG_LIR_Gen_1	160	168	PF02991	0.727
LIG_LIR_Nem_3	132	137	PF02991	0.595
LIG_LIR_Nem_3	160	165	PF02991	0.723
LIG_LIR_Nem_3	41	47	PF02991	0.623
LIG_LYPXL_S_1	43	47	PF13949	0.608
LIG_LYPXL_yS_3	44	47	PF13949	0.599
LIG_PCNA_PIPBox_1	109	118	PF02747	0.632
LIG_PCNA_yPIPBox_3	117	131	PF02747	0.603
LIG_SH2_CRK	150	154	PF00017	0.625
LIG_SH2_CRK	201	205	PF00017	0.671
LIG_SH2_CRK	29	33	PF00017	0.596
LIG_SH2_CRK	34	38	PF00017	0.592
LIG_SH2_STAP1	131	135	PF00017	0.603
LIG_SH2_STAT5	131	134	PF00017	0.602
LIG_SH2_STAT5	14	17	PF00017	0.559
LIG_SH2_STAT5	18	21	PF00017	0.538
LIG_SH2_STAT5	48	51	PF00017	0.585
LIG_SUMO_SIM_anti_2	75	83	PF11976	0.590
LIG_TRAF2_1	22	25	PF00917	0.545
LIG_WRC_WIRS_1	14	19	PF05994	0.574
LIG_WW_1	31	34	PF00397	0.620
MOD_CK1_1	161	167	PF00069	0.731
MOD_CK1_1	82	88	PF00069	0.656
MOD_CK2_1	19	25	PF00069	0.560
MOD_GlcNHglycan	154	157	PF01048	0.624
MOD_GlcNHglycan	3	6	PF01048	0.652
MOD_GSK3_1	111	118	PF00069	0.630
MOD_GSK3_1	135	142	PF00069	0.602
MOD_GSK3_1	157	164	PF00069	0.692
MOD_GSK3_1	16	23	PF00069	0.574
MOD_GSK3_1	79	86	PF00069	0.613
MOD_N-GLC_1	123	128	PF02516	0.590
MOD_NEK2_1	140	145	PF00069	0.623
MOD_NEK2_1	157	162	PF00069	0.373
MOD_NEK2_1	80	85	PF00069	0.606
MOD_NEK2_2	129	134	PF00069	0.595
MOD_PKA_2	158	164	PF00069	0.705
MOD_Plk_1	123	129	PF00069	0.587
MOD_Plk_4	123	129	PF00069	0.587
MOD_Plk_4	13	19	PF00069	0.572
TRG_ENDOCYTIC_2	131	134	PF00928	0.602
TRG_ENDOCYTIC_2	14	17	PF00928	0.559
TRG_ENDOCYTIC_2	150	153	PF00928	0.289
TRG_ENDOCYTIC_2	201	204	PF00928	0.676
TRG_ENDOCYTIC_2	44	47	PF00928	0.599
TRG_ER_diArg_1	198	200	PF00400	0.647

Homologs


Protein	Taxonomy	Sequence identity	Coverage
D5EXZ4	PRER2	26%	31%