Histone

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Histone

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

E9AIF6_LEIBR

TriTrypDb:

LbrM.20.5230 , LBRM2903_200066900

Length:

267

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AIF6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AIF6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	110	112	PF00675	0.629
CLV_NRD_NRD_1	129	131	PF00675	0.719
CLV_NRD_NRD_1	167	169	PF00675	0.620
CLV_NRD_NRD_1	184	186	PF00675	0.570
CLV_NRD_NRD_1	57	59	PF00675	0.622
CLV_NRD_NRD_1	71	73	PF00675	0.576
CLV_NRD_NRD_1	82	84	PF00675	0.526
CLV_PCSK_FUR_1	165	169	PF00082	0.575
CLV_PCSK_FUR_1	80	84	PF00082	0.575
CLV_PCSK_KEX2_1	110	112	PF00082	0.634
CLV_PCSK_KEX2_1	127	129	PF00082	0.729
CLV_PCSK_KEX2_1	167	169	PF00082	0.636
CLV_PCSK_KEX2_1	184	186	PF00082	0.602
CLV_PCSK_KEX2_1	252	254	PF00082	0.688
CLV_PCSK_KEX2_1	262	264	PF00082	0.592
CLV_PCSK_KEX2_1	71	73	PF00082	0.612
CLV_PCSK_KEX2_1	82	84	PF00082	0.526
CLV_PCSK_PC1ET2_1	127	129	PF00082	0.729
CLV_PCSK_PC1ET2_1	252	254	PF00082	0.688
CLV_PCSK_PC1ET2_1	262	264	PF00082	0.592
CLV_PCSK_PC7_1	180	186	PF00082	0.567
CLV_PCSK_SKI1_1	124	128	PF00082	0.716
CLV_PCSK_SKI1_1	224	228	PF00082	0.580
CLV_PCSK_SKI1_1	58	62	PF00082	0.650
DOC_CKS1_1	103	108	PF01111	0.545
DOC_CKS1_1	138	143	PF01111	0.576
DOC_CKS1_1	21	26	PF01111	0.636
DOC_CYCLIN_yClb1_LxF_4	8	14	PF00134	0.494
DOC_MAPK_gen_1	4	13	PF00069	0.598
DOC_PP4_FxxP_1	147	150	PF00568	0.559
DOC_PP4_FxxP_1	7	10	PF00568	0.623
DOC_USP7_MATH_1	196	200	PF00917	0.620
DOC_USP7_MATH_1	2	6	PF00917	0.669
DOC_USP7_MATH_1	208	212	PF00917	0.574
DOC_USP7_UBL2_3	113	117	PF12436	0.733
DOC_USP7_UBL2_3	127	131	PF12436	0.712
DOC_USP7_UBL2_3	239	243	PF12436	0.690
DOC_USP7_UBL2_3	248	252	PF12436	0.626
DOC_USP7_UBL2_3	41	45	PF12436	0.457
DOC_WW_Pin1_4	102	107	PF00397	0.554
DOC_WW_Pin1_4	137	142	PF00397	0.662
DOC_WW_Pin1_4	153	158	PF00397	0.581
DOC_WW_Pin1_4	170	175	PF00397	0.564
DOC_WW_Pin1_4	20	25	PF00397	0.646
DOC_WW_Pin1_4	95	100	PF00397	0.630
LIG_14-3-3_CanoR_1	122	127	PF00244	0.623
LIG_14-3-3_CanoR_1	167	174	PF00244	0.591
LIG_14-3-3_CanoR_1	184	191	PF00244	0.590
LIG_14-3-3_CanoR_1	201	208	PF00244	0.592
LIG_14-3-3_CanoR_1	237	243	PF00244	0.561
LIG_14-3-3_CanoR_1	58	64	PF00244	0.488
LIG_FHA_1	242	248	PF00498	0.592
LIG_FHA_2	21	27	PF00498	0.633
LIG_GBD_Chelix_1	47	55	PF00786	0.416
LIG_LIR_Apic_2	5	10	PF02991	0.625
LIG_MYND_1	92	96	PF01753	0.562
LIG_MYND_1	99	103	PF01753	0.540
LIG_SH2_STAT3	84	87	PF00017	0.578
LIG_SH3_1	100	106	PF00018	0.727
LIG_SH3_2	106	111	PF14604	0.512
LIG_SH3_2	132	137	PF14604	0.536
LIG_SH3_2	78	83	PF14604	0.573
LIG_SH3_2	92	97	PF14604	0.530
LIG_SH3_3	100	106	PF00018	0.712
LIG_SH3_3	129	135	PF00018	0.533
LIG_SH3_3	154	160	PF00018	0.603
LIG_SH3_3	230	236	PF00018	0.756
LIG_SH3_3	64	70	PF00018	0.561
LIG_SH3_3	72	78	PF00018	0.599
LIG_SH3_3	89	95	PF00018	0.688
LIG_SUMO_SIM_par_1	15	23	PF11976	0.659
LIG_TRAF2_1	23	26	PF00917	0.629
LIG_WW_3	107	111	PF00397	0.550
LIG_WW_3	94	98	PF00397	0.581
MOD_CDK_SPK_2	102	107	PF00069	0.528
MOD_CDK_SPK_2	153	158	PF00069	0.555
MOD_CDK_SPK_2	95	100	PF00069	0.568
MOD_CDK_SPxK_1	170	176	PF00069	0.562
MOD_CDK_SPxxK_3	20	27	PF00069	0.637
MOD_CK1_1	115	121	PF00069	0.761
MOD_CK1_1	199	205	PF00069	0.552
MOD_CK2_1	12	18	PF00069	0.660
MOD_CK2_1	20	26	PF00069	0.549
MOD_Cter_Amidation	213	216	PF01082	0.632
MOD_Cter_Amidation	260	263	PF01082	0.623
MOD_DYRK1A_RPxSP_1	137	141	PF00069	0.549
MOD_DYRK1A_RPxSP_1	153	157	PF00069	0.509
MOD_GlcNHglycan	114	117	PF01048	0.590
MOD_GlcNHglycan	177	180	PF01048	0.590
MOD_GlcNHglycan	212	215	PF01048	0.572
MOD_GSK3_1	159	166	PF00069	0.623
MOD_GSK3_1	196	203	PF00069	0.537
MOD_GSK3_1	237	244	PF00069	0.509
MOD_NEK2_1	183	188	PF00069	0.624
MOD_NEK2_1	247	252	PF00069	0.668
MOD_NEK2_2	238	243	PF00069	0.509
MOD_PIKK_1	160	166	PF00454	0.591
MOD_PIKK_1	83	89	PF00454	0.578
MOD_PK_1	145	151	PF00069	0.559
MOD_PKA_1	167	173	PF00069	0.650
MOD_PKA_1	71	77	PF00069	0.562
MOD_PKA_2	167	173	PF00069	0.644
MOD_PKA_2	175	181	PF00069	0.643
MOD_PKA_2	183	189	PF00069	0.560
MOD_PKA_2	200	206	PF00069	0.585
MOD_PKA_2	208	214	PF00069	0.564
MOD_PKA_2	71	77	PF00069	0.588
MOD_PKB_1	120	128	PF00069	0.543
MOD_PKB_1	165	173	PF00069	0.567
MOD_PKB_1	235	243	PF00069	0.512
MOD_Plk_4	228	234	PF00069	0.691
MOD_ProDKin_1	102	108	PF00069	0.552
MOD_ProDKin_1	137	143	PF00069	0.662
MOD_ProDKin_1	153	159	PF00069	0.580
MOD_ProDKin_1	170	176	PF00069	0.567
MOD_ProDKin_1	20	26	PF00069	0.640
MOD_ProDKin_1	95	101	PF00069	0.630
MOD_SUMO_for_1	116	119	PF00179	0.694
MOD_SUMO_rev_2	39	47	PF00179	0.408
MOD_SUMO_rev_2	54	60	PF00179	0.398
TRG_ER_diArg_1	109	111	PF00400	0.656
TRG_ER_diArg_1	120	123	PF00400	0.575
TRG_ER_diArg_1	165	168	PF00400	0.667
TRG_ER_diArg_1	183	185	PF00400	0.619
TRG_ER_diArg_1	234	237	PF00400	0.541
TRG_ER_diArg_1	3	6	PF00400	0.607
TRG_ER_diArg_1	70	72	PF00400	0.725
TRG_ER_diArg_1	80	83	PF00400	0.540
TRG_NLS_Bipartite_1	110	131	PF00514	0.550
TRG_NLS_Bipartite_1	248	266	PF00514	0.516
TRG_NLS_MonoCore_2	129	134	PF00514	0.535
TRG_NLS_MonoExtC_3	126	131	PF00514	0.721
TRG_NLS_MonoExtC_3	247	252	PF00514	0.511
TRG_NLS_MonoExtN_4	124	131	PF00514	0.717
TRG_NLS_MonoExtN_4	246	252	PF00514	0.542
TRG_NLS_MonoExtN_4	259	266	PF00514	0.507

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WW27	Leishmania donovani	53%	97%
A4HYU9	Leishmania infantum	53%	97%
E9AUP6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	51%	97%
Q4QCT9	Leishmania major	54%	100%