Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

transmembrane protein, conserved

Species:

Leishmania braziliensis

UniProt:

E9AIE4_LEIBR

TriTrypDb:

LbrM.20.5110 , LBRM2903_200065500

Length:

2115

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

E9AIE4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	1
GO:0004386	helicase activity	2	1
GO:0140640	catalytic activity, acting on a nucleic acid	2	1
GO:0140657	ATP-dependent activity	1	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1021	1025	PF00656	0.329
CLV_C14_Caspase3-7	1201	1205	PF00656	0.535
CLV_C14_Caspase3-7	1515	1519	PF00656	0.537
CLV_C14_Caspase3-7	1829	1833	PF00656	0.619
CLV_C14_Caspase3-7	2014	2018	PF00656	0.664
CLV_MEL_PAP_1	1016	1022	PF00089	0.454
CLV_NRD_NRD_1	1213	1215	PF00675	0.287
CLV_NRD_NRD_1	1431	1433	PF00675	0.370
CLV_NRD_NRD_1	1528	1530	PF00675	0.404
CLV_NRD_NRD_1	1922	1924	PF00675	0.418

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I3T6	Leptomonas seymouri	47%	97%
A0A1X0NWS7	Trypanosomatidae	28%	100%
A0A3S7WW09	Leishmania donovani	76%	100%
A4HYT5	Leishmania infantum	76%	100%
E9AUN1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	100%
Q4QCV3	Leishmania major	76%	99%
V5BVE6	Trypanosoma cruzi	31%	100%

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