Kinesin motor domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

E9AID1_LEIBR

TriTrypDb:

LbrM.20.4980 , LBRM2903_200064200

Length:

341

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AID1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AID1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	140	144	PF00656	0.588
CLV_C14_Caspase3-7	170	174	PF00656	0.511
CLV_NRD_NRD_1	14	16	PF00675	0.630
CLV_NRD_NRD_1	286	288	PF00675	0.594
CLV_NRD_NRD_1	61	63	PF00675	0.639
CLV_PCSK_KEX2_1	14	16	PF00082	0.625
CLV_PCSK_KEX2_1	47	49	PF00082	0.512
CLV_PCSK_KEX2_1	63	65	PF00082	0.667
CLV_PCSK_PC1ET2_1	47	49	PF00082	0.486
CLV_PCSK_PC1ET2_1	63	65	PF00082	0.542
CLV_PCSK_SKI1_1	164	168	PF00082	0.500
CLV_PCSK_SKI1_1	256	260	PF00082	0.475
CLV_PCSK_SKI1_1	308	312	PF00082	0.341
CLV_PCSK_SKI1_1	66	70	PF00082	0.585
DEG_APCC_DBOX_1	320	328	PF00400	0.344
DOC_MAPK_gen_1	225	232	PF00069	0.364
DOC_MAPK_JIP1_4	300	306	PF00069	0.488
DOC_USP7_MATH_1	165	169	PF00917	0.522
DOC_USP7_MATH_1	181	185	PF00917	0.659
DOC_USP7_MATH_1	6	10	PF00917	0.512
DOC_WW_Pin1_4	145	150	PF00397	0.535
DOC_WW_Pin1_4	261	266	PF00397	0.516
DOC_WW_Pin1_4	4	9	PF00397	0.642
LIG_14-3-3_CanoR_1	287	293	PF00244	0.497
LIG_14-3-3_CanoR_1	321	325	PF00244	0.376
LIG_Actin_WH2_2	320	338	PF00022	0.372
LIG_BIR_III_2	146	150	PF00653	0.595
LIG_Clathr_ClatBox_1	86	90	PF01394	0.492
LIG_eIF4E_1	190	196	PF01652	0.526
LIG_FHA_1	273	279	PF00498	0.468
LIG_FHA_1	28	34	PF00498	0.602
LIG_FHA_1	5	11	PF00498	0.522
LIG_FHA_2	37	43	PF00498	0.561
LIG_SH2_STAT5	231	234	PF00017	0.512
LIG_SUMO_SIM_anti_2	302	309	PF11976	0.487
LIG_SUMO_SIM_par_1	275	281	PF11976	0.413
LIG_TRAF2_1	191	194	PF00917	0.590
LIG_TRAF2_1	241	244	PF00917	0.488
LIG_WRC_WIRS_1	128	133	PF05994	0.535
MOD_CDK_SPxK_1	261	267	PF00069	0.519
MOD_CDK_SPxxK_3	4	11	PF00069	0.617
MOD_CK1_1	184	190	PF00069	0.571
MOD_CK1_1	4	10	PF00069	0.682
MOD_CK2_1	312	318	PF00069	0.496
MOD_CK2_1	323	329	PF00069	0.390
MOD_CK2_1	334	340	PF00069	0.532
MOD_CK2_1	36	42	PF00069	0.564
MOD_GlcNHglycan	167	170	PF01048	0.591
MOD_GlcNHglycan	3	6	PF01048	0.780
MOD_GSK3_1	141	148	PF00069	0.527
MOD_GSK3_1	181	188	PF00069	0.585
MOD_N-GLC_1	181	186	PF02516	0.735
MOD_NEK2_1	1	6	PF00069	0.816
MOD_NEK2_1	283	288	PF00069	0.473
MOD_NEK2_2	181	186	PF00069	0.642
MOD_PIKK_1	312	318	PF00454	0.472
MOD_PIKK_1	9	15	PF00454	0.681
MOD_PKA_1	225	231	PF00069	0.349
MOD_PKA_2	320	326	PF00069	0.343
MOD_PKA_2	335	341	PF00069	0.463
MOD_Plk_1	181	187	PF00069	0.607
MOD_Plk_2-3	141	147	PF00069	0.583
MOD_Plk_4	127	133	PF00069	0.504
MOD_Plk_4	148	154	PF00069	0.614
MOD_Plk_4	225	231	PF00069	0.385
MOD_Plk_4	302	308	PF00069	0.517
MOD_ProDKin_1	145	151	PF00069	0.533
MOD_ProDKin_1	261	267	PF00069	0.519
MOD_ProDKin_1	4	10	PF00069	0.643
MOD_SUMO_for_1	46	49	PF00179	0.459
TRG_DiLeu_BaEn_1	279	284	PF01217	0.406

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCL3	Leptomonas seymouri	52%	96%
A0A3Q8IAT4	Leishmania donovani	73%	95%
A4HYN8	Leishmania infantum	73%	95%
E9AUL8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	75%	95%
Q4QCW6	Leishmania major	74%	100%