Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

conserved protein, unknown function

Species:

Leishmania braziliensis

UniProt:

E9AIC7_LEIBR

TriTrypDb:

LbrM.20.4940 , LBRM2903_200063700

Length:

929

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AIC7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AIC7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	188	192	PF00656	0.879
CLV_C14_Caspase3-7	236	240	PF00656	0.631
CLV_C14_Caspase3-7	311	315	PF00656	0.609
CLV_C14_Caspase3-7	668	672	PF00656	0.846
CLV_C14_Caspase3-7	73	77	PF00656	0.804
CLV_NRD_NRD_1	381	383	PF00675	0.614
CLV_NRD_NRD_1	596	598	PF00675	0.611
CLV_NRD_NRD_1	601	603	PF00675	0.540
CLV_NRD_NRD_1	61	63	PF00675	0.890
CLV_NRD_NRD_1	764	766	PF00675	0.656
CLV_NRD_NRD_1	816	818	PF00675	0.673
CLV_NRD_NRD_1	93	95	PF00675	0.654
CLV_PCSK_KEX2_1	320	322	PF00082	0.695
CLV_PCSK_KEX2_1	381	383	PF00082	0.614
CLV_PCSK_KEX2_1	596	598	PF00082	0.611
CLV_PCSK_KEX2_1	600	602	PF00082	0.576
CLV_PCSK_KEX2_1	853	855	PF00082	0.876
CLV_PCSK_KEX2_1	93	95	PF00082	0.654
CLV_PCSK_PC1ET2_1	320	322	PF00082	0.695
CLV_PCSK_PC1ET2_1	853	855	PF00082	0.876
CLV_PCSK_PC7_1	596	602	PF00082	0.631
CLV_PCSK_SKI1_1	317	321	PF00082	0.652
CLV_PCSK_SKI1_1	382	386	PF00082	0.618
CLV_PCSK_SKI1_1	470	474	PF00082	0.835
CLV_PCSK_SKI1_1	616	620	PF00082	0.607
CLV_PCSK_SKI1_1	751	755	PF00082	0.653
CLV_PCSK_SKI1_1	757	761	PF00082	0.537
CLV_PCSK_SKI1_1	834	838	PF00082	0.769
DEG_APCC_DBOX_1	85	93	PF00400	0.648
DEG_SPOP_SBC_1	131	135	PF00917	0.894
DEG_SPOP_SBC_1	150	154	PF00917	0.519
DOC_CDC14_PxL_1	640	648	PF14671	0.691
DOC_CKS1_1	143	148	PF01111	0.866
DOC_CKS1_1	442	447	PF01111	0.657
DOC_CKS1_1	647	652	PF01111	0.797
DOC_MAPK_gen_1	286	294	PF00069	0.667
DOC_MAPK_gen_1	596	605	PF00069	0.623
DOC_MAPK_MEF2A_6	825	833	PF00069	0.627
DOC_PP2B_LxvP_1	194	197	PF13499	0.858
DOC_PP2B_LxvP_1	415	418	PF13499	0.720
DOC_PP2B_LxvP_1	431	434	PF13499	0.370
DOC_PP2B_LxvP_1	516	519	PF13499	0.848
DOC_PP2B_LxvP_1	542	545	PF13499	0.826
DOC_PP4_FxxP_1	426	429	PF00568	0.701
DOC_PP4_FxxP_1	651	654	PF00568	0.824
DOC_PP4_FxxP_1	727	730	PF00568	0.617
DOC_USP7_MATH_1	150	154	PF00917	0.851
DOC_USP7_MATH_1	184	188	PF00917	0.879
DOC_USP7_MATH_1	204	208	PF00917	0.426
DOC_USP7_MATH_1	3	7	PF00917	0.610
DOC_USP7_MATH_1	434	438	PF00917	0.635
DOC_USP7_MATH_1	472	476	PF00917	0.837
DOC_USP7_MATH_1	491	495	PF00917	0.521
DOC_USP7_MATH_1	519	523	PF00917	0.834
DOC_USP7_MATH_1	614	618	PF00917	0.615
DOC_USP7_MATH_1	654	658	PF00917	0.824
DOC_USP7_MATH_1	846	850	PF00917	0.870
DOC_USP7_UBL2_3	740	744	PF12436	0.631
DOC_WW_Pin1_4	139	144	PF00397	0.884
DOC_WW_Pin1_4	36	41	PF00397	0.800
DOC_WW_Pin1_4	441	446	PF00397	0.653
DOC_WW_Pin1_4	495	500	PF00397	0.855
DOC_WW_Pin1_4	568	573	PF00397	0.862
DOC_WW_Pin1_4	646	651	PF00397	0.776
DOC_WW_Pin1_4	777	782	PF00397	0.658
LIG_14-3-3_CanoR_1	56	64	PF00244	0.887
LIG_14-3-3_CanoR_1	674	682	PF00244	0.861
LIG_14-3-3_CanoR_1	695	699	PF00244	0.806
LIG_14-3-3_CanoR_1	798	806	PF00244	0.685
LIG_Actin_RPEL_3	352	371	PF02755	0.628
LIG_Actin_WH2_2	736	753	PF00022	0.641
LIG_BRCT_BRCA1_1	723	727	PF00533	0.590
LIG_Clathr_ClatBox_1	708	712	PF01394	0.611
LIG_FHA_1	348	354	PF00498	0.643
LIG_FHA_1	444	450	PF00498	0.675
LIG_FHA_1	589	595	PF00498	0.613
LIG_FHA_1	635	641	PF00498	0.624
LIG_FHA_1	660	666	PF00498	0.846
LIG_FHA_1	686	692	PF00498	0.858
LIG_FHA_1	778	784	PF00498	0.649
LIG_FHA_1	826	832	PF00498	0.620
LIG_FHA_2	131	137	PF00498	0.896
LIG_FHA_2	159	165	PF00498	0.850
LIG_FHA_2	225	231	PF00498	0.638
LIG_FHA_2	243	249	PF00498	0.325
LIG_FHA_2	36	42	PF00498	0.804
LIG_FHA_2	385	391	PF00498	0.642
LIG_FHA_2	634	640	PF00498	0.627
LIG_FHA_2	666	672	PF00498	0.848
LIG_FHA_2	765	771	PF00498	0.674
LIG_LIR_Apic_2	648	654	PF02991	0.811
LIG_LIR_Apic_2	724	730	PF02991	0.606
LIG_LIR_Gen_1	10	20	PF02991	0.632
LIG_LIR_Gen_1	215	226	PF02991	0.659
LIG_LIR_Gen_1	232	242	PF02991	0.322
LIG_LIR_Gen_1	609	618	PF02991	0.627
LIG_LIR_Gen_1	619	630	PF02991	0.416
LIG_LIR_Nem_3	10	16	PF02991	0.611
LIG_LIR_Nem_3	211	217	PF02991	0.692
LIG_LIR_Nem_3	232	237	PF02991	0.620
LIG_LIR_Nem_3	268	274	PF02991	0.630
LIG_LIR_Nem_3	314	319	PF02991	0.626
LIG_LIR_Nem_3	609	615	PF02991	0.633
LIG_LIR_Nem_3	619	625	PF02991	0.414
LIG_LIR_Nem_3	735	741	PF02991	0.623
LIG_LYPXL_SIV_4	452	460	PF13949	0.778
LIG_MLH1_MIPbox_1	723	727	PF16413	0.590
LIG_MYND_1	575	579	PF01753	0.811
LIG_MYND_1	730	734	PF01753	0.646
LIG_NRBOX	388	394	PF00104	0.654
LIG_NRBOX	410	416	PF00104	0.668
LIG_PCNA_PIPBox_1	24	33	PF02747	0.612
LIG_PCNA_yPIPBox_3	381	393	PF02747	0.632
LIG_Pex14_1	722	726	PF04695	0.589
LIG_Pex14_2	214	218	PF04695	0.679
LIG_PTB_Apo_2	447	454	PF02174	0.706
LIG_PTB_Phospho_1	447	453	PF10480	0.701
LIG_REV1ctd_RIR_1	649	653	PF16727	0.811
LIG_SH2_CRK	612	616	PF00017	0.634
LIG_SH2_GRB2like	100	103	PF00017	0.671
LIG_SH2_GRB2like	448	451	PF00017	0.679
LIG_SH2_GRB2like	811	814	PF00017	0.665
LIG_SH2_NCK_1	453	457	PF00017	0.774
LIG_SH2_SRC	100	103	PF00017	0.671
LIG_SH2_SRC	448	451	PF00017	0.679
LIG_SH2_STAT3	811	814	PF00017	0.665
LIG_SH2_STAT5	15	18	PF00017	0.639
LIG_SH2_STAT5	304	307	PF00017	0.575
LIG_SH2_STAT5	31	34	PF00017	0.357
LIG_SH2_STAT5	410	413	PF00017	0.665
LIG_SH2_STAT5	443	446	PF00017	0.648
LIG_SH2_STAT5	448	451	PF00017	0.591
LIG_SH2_STAT5	775	778	PF00017	0.654
LIG_SH2_STAT5	811	814	PF00017	0.665
LIG_SH3_3	140	146	PF00018	0.875
LIG_SH3_3	251	257	PF00018	0.700
LIG_SH3_3	267	273	PF00018	0.369
LIG_SH3_3	433	439	PF00018	0.633
LIG_SH3_3	541	547	PF00018	0.823
LIG_SH3_3	569	575	PF00018	0.858
LIG_SH3_3	644	650	PF00018	0.746
LIG_SH3_3	676	682	PF00018	0.862
LIG_SH3_3	696	702	PF00018	0.400
LIG_SH3_3	864	870	PF00018	0.873
LIG_SH3_3	915	921	PF00018	0.863
LIG_SH3_4	63	70	PF00018	0.881
LIG_SUMO_SIM_anti_2	362	368	PF11976	0.600
LIG_SUMO_SIM_par_1	41	46	PF11976	0.864
LIG_TRAF2_1	134	137	PF00917	0.895
LIG_TRAF2_1	174	177	PF00917	0.874
LIG_TYR_ITIM	302	307	PF00017	0.575
LIG_UBA3_1	109	118	PF00899	0.753
LIG_WW_3	417	421	PF00397	0.775
MOD_CDK_SPK_2	777	782	PF00069	0.658
MOD_CDK_SPxxK_3	142	149	PF00069	0.871
MOD_CDK_SPxxK_3	495	502	PF00069	0.861
MOD_CDK_SPxxK_3	646	653	PF00069	0.788
MOD_CK1_1	11	17	PF00069	0.610
MOD_CK1_1	135	141	PF00069	0.891
MOD_CK1_1	142	148	PF00069	0.748
MOD_CK1_1	154	160	PF00069	0.522
MOD_CK1_1	179	185	PF00069	0.875
MOD_CK1_1	187	193	PF00069	0.739
MOD_CK1_1	224	230	PF00069	0.650
MOD_CK1_1	339	345	PF00069	0.750
MOD_CK1_1	437	443	PF00069	0.653
MOD_CK1_1	463	469	PF00069	0.829
MOD_CK1_1	494	500	PF00069	0.853
MOD_CK1_1	634	640	PF00069	0.627
MOD_CK1_1	657	663	PF00069	0.834
MOD_CK1_1	70	76	PF00069	0.839
MOD_CK1_1	855	861	PF00069	0.882
MOD_CK2_1	130	136	PF00069	0.896
MOD_CK2_1	182	188	PF00069	0.880
MOD_CK2_1	204	210	PF00069	0.758
MOD_CK2_1	242	248	PF00069	0.638
MOD_CK2_1	321	327	PF00069	0.730
MOD_CK2_1	337	343	PF00069	0.513
MOD_CK2_1	614	620	PF00069	0.610
MOD_CK2_1	633	639	PF00069	0.298
MOD_CK2_1	846	852	PF00069	0.874
MOD_CK2_1	892	898	PF00069	0.848
MOD_Cter_Amidation	379	382	PF01082	0.602
MOD_Cter_Amidation	598	601	PF01082	0.627
MOD_Cter_Amidation	815	818	PF01082	0.676
MOD_GlcNHglycan	126	129	PF01048	0.888
MOD_GlcNHglycan	139	142	PF01048	0.663
MOD_GlcNHglycan	153	156	PF01048	0.607
MOD_GlcNHglycan	200	204	PF01048	0.828
MOD_GlcNHglycan	250	253	PF01048	0.667
MOD_GlcNHglycan	354	357	PF01048	0.681
MOD_GlcNHglycan	439	442	PF01048	0.666
MOD_GlcNHglycan	46	50	PF01048	0.878
MOD_GlcNHglycan	494	497	PF01048	0.857
MOD_GlcNHglycan	507	511	PF01048	0.635
MOD_GlcNHglycan	516	519	PF01048	0.690
MOD_GlcNHglycan	534	537	PF01048	0.499
MOD_GlcNHglycan	612	615	PF01048	0.637
MOD_GlcNHglycan	656	659	PF01048	0.828
MOD_GlcNHglycan	704	707	PF01048	0.632
MOD_GlcNHglycan	734	737	PF01048	0.674
MOD_GlcNHglycan	800	803	PF01048	0.689
MOD_GlcNHglycan	854	857	PF01048	0.878
MOD_GlcNHglycan	886	889	PF01048	0.856
MOD_GlcNHglycan	894	897	PF01048	0.708
MOD_GlcNHglycan	911	914	PF01048	0.568
MOD_GSK3_1	122	129	PF00069	0.875
MOD_GSK3_1	131	138	PF00069	0.737
MOD_GSK3_1	150	157	PF00069	0.522
MOD_GSK3_1	179	186	PF00069	0.876
MOD_GSK3_1	212	219	PF00069	0.681
MOD_GSK3_1	256	263	PF00069	0.792
MOD_GSK3_1	3	10	PF00069	0.622
MOD_GSK3_1	347	354	PF00069	0.639
MOD_GSK3_1	437	444	PF00069	0.656
MOD_GSK3_1	460	467	PF00069	0.825
MOD_GSK3_1	468	475	PF00069	0.695
MOD_GSK3_1	491	498	PF00069	0.856
MOD_GSK3_1	508	515	PF00069	0.568
MOD_GSK3_1	606	613	PF00069	0.633
MOD_GSK3_1	652	659	PF00069	0.826
MOD_GSK3_1	66	73	PF00069	0.869
MOD_GSK3_1	660	667	PF00069	0.707
MOD_GSK3_1	670	677	PF00069	0.535
MOD_GSK3_1	717	724	PF00069	0.586
MOD_GSK3_1	728	735	PF00069	0.454
MOD_GSK3_1	821	828	PF00069	0.630
MOD_GSK3_1	854	861	PF00069	0.882
MOD_GSK3_1	882	889	PF00069	0.854
MOD_LATS_1	122	128	PF00433	0.872
MOD_N-GLC_1	224	229	PF02516	0.655
MOD_N-GLC_1	357	362	PF02516	0.656
MOD_N-GLC_1	532	537	PF02516	0.816
MOD_N-GLC_1	610	615	PF02516	0.636
MOD_N-GLC_1	839	844	PF02516	0.832
MOD_N-GLC_1	872	877	PF02516	0.862
MOD_N-GLC_2	170	172	PF02516	0.867
MOD_NEK2_1	347	352	PF00069	0.628
MOD_NEK2_1	460	465	PF00069	0.824
MOD_NEK2_1	512	517	PF00069	0.864
MOD_NEK2_1	631	636	PF00069	0.629
MOD_NEK2_1	721	726	PF00069	0.587
MOD_NEK2_1	821	826	PF00069	0.635
MOD_NEK2_2	722	727	PF00069	0.590
MOD_NMyristoyl	1	7	PF02799	0.624
MOD_PIKK_1	454	460	PF00454	0.790
MOD_PIKK_1	580	586	PF00454	0.683
MOD_PIKK_1	694	700	PF00454	0.801
MOD_PKA_2	16	22	PF00069	0.642
MOD_PKA_2	55	61	PF00069	0.887
MOD_PKA_2	673	679	PF00069	0.859
MOD_PKA_2	694	700	PF00069	0.801
MOD_PKA_2	764	770	PF00069	0.667
MOD_Plk_1	190	196	PF00069	0.872
MOD_Plk_1	357	363	PF00069	0.649
MOD_Plk_1	610	616	PF00069	0.633
MOD_Plk_1	631	637	PF00069	0.632
MOD_Plk_1	7	13	PF00069	0.628
MOD_Plk_1	871	877	PF00069	0.862
MOD_Plk_4	154	160	PF00069	0.854
MOD_Plk_4	410	416	PF00069	0.668
MOD_Plk_4	717	723	PF00069	0.586
MOD_Plk_4	728	734	PF00069	0.450
MOD_Plk_4	8	14	PF00069	0.619
MOD_Plk_4	825	831	PF00069	0.622
MOD_ProDKin_1	139	145	PF00069	0.884
MOD_ProDKin_1	36	42	PF00069	0.804
MOD_ProDKin_1	441	447	PF00069	0.663
MOD_ProDKin_1	495	501	PF00069	0.859
MOD_ProDKin_1	568	574	PF00069	0.861
MOD_ProDKin_1	646	652	PF00069	0.782
MOD_ProDKin_1	777	783	PF00069	0.651
MOD_SUMO_for_1	743	746	PF00179	0.652
MOD_SUMO_rev_2	395	401	PF00179	0.706
MOD_SUMO_rev_2	475	482	PF00179	0.834
MOD_SUMO_rev_2	685	691	PF00179	0.860
TRG_DiLeu_BaEn_1	642	647	PF01217	0.693
TRG_DiLeu_BaEn_2	342	348	PF01217	0.668
TRG_DiLeu_BaEn_2	619	625	PF01217	0.589
TRG_DiLeu_BaEn_4	795	801	PF01217	0.679
TRG_DiLeu_BaLyEn_6	341	346	PF01217	0.705
TRG_DiLeu_BaLyEn_6	426	431	PF01217	0.675
TRG_DiLeu_BaLyEn_6	779	784	PF01217	0.638
TRG_ENDOCYTIC_2	217	220	PF00928	0.661
TRG_ENDOCYTIC_2	304	307	PF00928	0.575
TRG_ENDOCYTIC_2	612	615	PF00928	0.637
TRG_ENDOCYTIC_2	826	829	PF00928	0.615
TRG_ER_diArg_1	596	598	PF00400	0.611
TRG_ER_diArg_1	600	602	PF00400	0.576
TRG_ER_diArg_1	92	94	PF00400	0.651
TRG_Pf-PMV_PEXEL_1	502	507	PF00026	0.862
TRG_Pf-PMV_PEXEL_1	616	620	PF00026	0.607
TRG_Pf-PMV_PEXEL_1	788	793	PF00026	0.659
TRG_Pf-PMV_PEXEL_1	798	803	PF00026	0.518