MORN repeat family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

MORN repeat, putative

Species:

Leishmania braziliensis

UniProt:

E9AIB5_LEIBR

TriTrypDb:

LbrM.20.4820 , LBRM2903_200062300

Length:

435

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005829	cytosol	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9AIB5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AIB5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	138	142	PF00656	0.541
CLV_C14_Caspase3-7	143	147	PF00656	0.500
CLV_C14_Caspase3-7	72	76	PF00656	0.726
CLV_NRD_NRD_1	113	115	PF00675	0.574
CLV_PCSK_KEX2_1	113	115	PF00082	0.574
CLV_PCSK_KEX2_1	217	219	PF00082	0.432
CLV_PCSK_KEX2_1	64	66	PF00082	0.549
CLV_PCSK_PC1ET2_1	217	219	PF00082	0.432
CLV_PCSK_PC1ET2_1	64	66	PF00082	0.549
CLV_PCSK_SKI1_1	313	317	PF00082	0.455
CLV_PCSK_SKI1_1	64	68	PF00082	0.653
DEG_Nend_UBRbox_2	1	3	PF02207	0.550
DEG_SPOP_SBC_1	45	49	PF00917	0.575
DOC_MAPK_gen_1	286	295	PF00069	0.332
DOC_PP2B_LxvP_1	293	296	PF13499	0.332
DOC_PP4_FxxP_1	332	335	PF00568	0.482
DOC_PP4_FxxP_1	339	342	PF00568	0.502
DOC_USP7_MATH_1	126	130	PF00917	0.697
DOC_USP7_MATH_1	335	339	PF00917	0.537
DOC_USP7_MATH_1	73	77	PF00917	0.599
DOC_USP7_UBL2_3	260	264	PF12436	0.255
DOC_WW_Pin1_4	41	46	PF00397	0.786
LIG_14-3-3_CanoR_1	65	71	PF00244	0.543
LIG_14-3-3_CanoR_1	97	105	PF00244	0.564
LIG_Actin_WH2_2	158	174	PF00022	0.419
LIG_BRCT_BRCA1_1	128	132	PF00533	0.542
LIG_BRCT_BRCA1_1	50	54	PF00533	0.574
LIG_BRCT_BRCA1_2	50	56	PF00533	0.571
LIG_DLG_GKlike_1	371	379	PF00625	0.551
LIG_FHA_1	356	362	PF00498	0.552
LIG_FHA_1	55	61	PF00498	0.626
LIG_FHA_1	65	71	PF00498	0.711
LIG_FHA_2	314	320	PF00498	0.479
LIG_FHA_2	364	370	PF00498	0.545
LIG_FHA_2	70	76	PF00498	0.700
LIG_FHA_2	9	15	PF00498	0.633
LIG_KLC1_Yacidic_2	233	238	PF13176	0.243
LIG_LIR_Apic_2	330	335	PF02991	0.477
LIG_LIR_Apic_2	337	342	PF02991	0.501
LIG_LIR_Gen_1	146	156	PF02991	0.397
LIG_LIR_Nem_3	146	152	PF02991	0.499
LIG_LIR_Nem_3	157	161	PF02991	0.334
LIG_LIR_Nem_3	242	247	PF02991	0.318
LIG_LIR_Nem_3	309	315	PF02991	0.443
LIG_Pex14_2	278	282	PF04695	0.332
LIG_REV1ctd_RIR_1	309	317	PF16727	0.447
LIG_SH2_CRK	247	251	PF00017	0.332
LIG_SH2_SRC	294	297	PF00017	0.281
LIG_SH2_SRC	301	304	PF00017	0.353
LIG_SH2_STAT3	161	164	PF00017	0.390
LIG_SH2_STAT5	161	164	PF00017	0.389
LIG_SH2_STAT5	186	189	PF00017	0.332
LIG_SH2_STAT5	224	227	PF00017	0.321
LIG_SH2_STAT5	236	239	PF00017	0.321
LIG_SH2_STAT5	247	250	PF00017	0.268
LIG_SH2_STAT5	294	297	PF00017	0.296
LIG_SH2_STAT5	301	304	PF00017	0.367
LIG_SH3_3	339	345	PF00018	0.598
LIG_SH3_3	39	45	PF00018	0.805
LIG_SH3_3	423	429	PF00018	0.539
LIG_SUMO_SIM_anti_2	150	157	PF11976	0.343
LIG_TRAF2_1	412	415	PF00917	0.542
MOD_CK1_1	131	137	PF00069	0.634
MOD_CK1_1	409	415	PF00069	0.783
MOD_CK1_1	44	50	PF00069	0.743
MOD_CK1_1	55	61	PF00069	0.657
MOD_CK2_1	313	319	PF00069	0.468
MOD_CK2_1	363	369	PF00069	0.547
MOD_CK2_1	409	415	PF00069	0.546
MOD_CK2_1	56	62	PF00069	0.670
MOD_Cter_Amidation	215	218	PF01082	0.332
MOD_Cter_Amidation	284	287	PF01082	0.332
MOD_GlcNHglycan	116	119	PF01048	0.633
MOD_GlcNHglycan	128	131	PF01048	0.776
MOD_GlcNHglycan	181	184	PF01048	0.240
MOD_GlcNHglycan	218	221	PF01048	0.332
MOD_GlcNHglycan	22	25	PF01048	0.753
MOD_GlcNHglycan	352	355	PF01048	0.663
MOD_GlcNHglycan	50	53	PF01048	0.687
MOD_GlcNHglycan	86	89	PF01048	0.521
MOD_GSK3_1	126	133	PF00069	0.654
MOD_GSK3_1	135	142	PF00069	0.683
MOD_GSK3_1	20	27	PF00069	0.692
MOD_GSK3_1	399	406	PF00069	0.688
MOD_GSK3_1	41	48	PF00069	0.793
MOD_GSK3_1	410	417	PF00069	0.662
MOD_GSK3_1	50	57	PF00069	0.706
MOD_GSK3_1	64	71	PF00069	0.725
MOD_GSK3_1	8	15	PF00069	0.691
MOD_GSK3_1	84	91	PF00069	0.515
MOD_GSK3_1	93	100	PF00069	0.684
MOD_N-GLC_1	106	111	PF02516	0.569
MOD_N-GLC_1	139	144	PF02516	0.607
MOD_NEK2_1	132	137	PF00069	0.554
MOD_NEK2_1	26	31	PF00069	0.599
MOD_NEK2_1	363	368	PF00069	0.546
MOD_NEK2_1	54	59	PF00069	0.585
MOD_PK_1	56	62	PF00069	0.548
MOD_PKA_1	64	70	PF00069	0.546
MOD_PKA_2	268	274	PF00069	0.279
MOD_PKA_2	335	341	PF00069	0.665
MOD_PKA_2	64	70	PF00069	0.585
MOD_PKA_2	93	99	PF00069	0.561
MOD_Plk_4	268	274	PF00069	0.279
MOD_ProDKin_1	41	47	PF00069	0.787
MOD_SUMO_rev_2	59	66	PF00179	0.722
TRG_DiLeu_BaEn_4	414	420	PF01217	0.532
TRG_ENDOCYTIC_2	232	235	PF00928	0.306
TRG_ENDOCYTIC_2	247	250	PF00928	0.331
TRG_ER_diArg_1	112	114	PF00400	0.563
TRG_Pf-PMV_PEXEL_1	381	385	PF00026	0.488

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDL7	Leptomonas seymouri	63%	90%
A0A3Q8IAI5	Leishmania donovani	63%	100%
A4HYQ3	Leishmania infantum	63%	100%
E9AUK2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	63%	100%
Q4QCY2	Leishmania major	63%	100%