LeishMANIAdb
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CTP_transf_like domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
CTP_transf_like domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
E9AIA7_LEIBR
TriTrypDb:
LbrM.20.4740 , LBRM2903_200061300 *
Length:
557

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
TermNameLevelCount
GO:0005634 nucleus 5 1
GO:0005737 cytoplasm 2 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1
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Expansion

Sequence features

E9AIA7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AIA7

Function

Biological processes
TermNameLevelCount
GO:0006139 nucleobase-containing compound metabolic process 3 1
GO:0006725 cellular aromatic compound metabolic process 3 1
GO:0006753 nucleoside phosphate metabolic process 4 1
GO:0006793 phosphorus metabolic process 3 1
GO:0006796 phosphate-containing compound metabolic process 4 1
GO:0006807 nitrogen compound metabolic process 2 1
GO:0008152 metabolic process 1 4
GO:0009058 biosynthetic process 2 4
GO:0009117 nucleotide metabolic process 5 1
GO:0009165 nucleotide biosynthetic process 6 1
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Molecular functions
TermNameLevelCount
GO:0000309 nicotinamide-nucleotide adenylyltransferase activity 6 1
GO:0003824 catalytic activity 1 4
GO:0016462 pyrophosphatase activity 5 1
GO:0016740 transferase activity 2 1
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 1
GO:0016779 nucleotidyltransferase activity 4 1
GO:0016787 hydrolase activity 2 1
GO:0016817 hydrolase activity, acting on acid anhydrides 3 1
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 1
GO:0016887 ATP hydrolysis activity 7 1
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 150 154 PF00656 0.549
CLV_C14_Caspase3-7 209 213 PF00656 0.535
CLV_C14_Caspase3-7 293 297 PF00656 0.458
CLV_NRD_NRD_1 30 32 PF00675 0.517
CLV_NRD_NRD_1 349 351 PF00675 0.431
CLV_NRD_NRD_1 419 421 PF00675 0.292
CLV_NRD_NRD_1 499 501 PF00675 0.292
CLV_NRD_NRD_1 547 549 PF00675 0.532
CLV_NRD_NRD_1 552 554 PF00675 0.573
CLV_NRD_NRD_1 72 74 PF00675 0.307
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P7H4 Leptomonas seymouri 52% 100%
A0A3S7WVU1 Leishmania donovani 79% 100%
A4HYR1 Leishmania infantum 79% 100%
E9AUJ4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 77% 100%
Q4QCZ0 Leishmania major 78% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS