LeishMANIAdb
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AD domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
AD domain-containing protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania braziliensis
UniProt:
E9AI73_LEIBR
TriTrypDb:
LbrM.20.4380 , LBRM2903_200057800 *
Length:
303

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AI73
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AI73

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 116 118 PF00675 0.779
CLV_NRD_NRD_1 232 234 PF00675 0.636
CLV_NRD_NRD_1 46 48 PF00675 0.478
CLV_PCSK_KEX2_1 116 118 PF00082 0.776
CLV_PCSK_KEX2_1 241 243 PF00082 0.715
CLV_PCSK_KEX2_1 46 48 PF00082 0.478
CLV_PCSK_PC1ET2_1 241 243 PF00082 0.461
CLV_PCSK_SKI1_1 234 238 PF00082 0.566
CLV_PCSK_SKI1_1 252 256 PF00082 0.406
DEG_Nend_Nbox_1 1 3 PF02207 0.513
DEG_SPOP_SBC_1 155 159 PF00917 0.609
DOC_MAPK_gen_1 292 300 PF00069 0.411
DOC_PP2B_LxvP_1 152 155 PF13499 0.477
DOC_PP2B_LxvP_1 298 301 PF13499 0.491
DOC_PP4_FxxP_1 42 45 PF00568 0.465
DOC_PP4_FxxP_1 58 61 PF00568 0.438
DOC_USP7_MATH_1 131 135 PF00917 0.541
DOC_USP7_MATH_1 45 49 PF00917 0.475
DOC_USP7_MATH_1 77 81 PF00917 0.605
DOC_USP7_UBL2_3 234 238 PF12436 0.509
DOC_USP7_UBL2_3 252 256 PF12436 0.374
DOC_WW_Pin1_4 106 111 PF00397 0.582
DOC_WW_Pin1_4 157 162 PF00397 0.638
DOC_WW_Pin1_4 22 27 PF00397 0.521
DOC_WW_Pin1_4 70 75 PF00397 0.640
DOC_WW_Pin1_4 87 92 PF00397 0.495
DOC_WW_Pin1_4 9 14 PF00397 0.504
LIG_14-3-3_CanoR_1 153 163 PF00244 0.631
LIG_14-3-3_CanoR_1 180 185 PF00244 0.551
LIG_14-3-3_CanoR_1 233 240 PF00244 0.643
LIG_14-3-3_CanoR_1 242 250 PF00244 0.400
LIG_14-3-3_CanoR_1 47 57 PF00244 0.478
LIG_14-3-3_CanoR_1 84 88 PF00244 0.529
LIG_BIR_III_4 190 194 PF00653 0.531
LIG_BRCT_BRCA1_1 54 58 PF00533 0.477
LIG_Clathr_ClatBox_1 168 172 PF01394 0.533
LIG_DCNL_PONY_1 1 4 PF03556 0.511
LIG_FHA_1 122 128 PF00498 0.531
LIG_FHA_1 136 142 PF00498 0.439
LIG_FHA_1 147 153 PF00498 0.511
LIG_FHA_1 172 178 PF00498 0.525
LIG_FHA_1 200 206 PF00498 0.516
LIG_FHA_1 258 264 PF00498 0.355
LIG_FHA_1 29 35 PF00498 0.473
LIG_FHA_2 107 113 PF00498 0.536
LIG_FHA_2 227 233 PF00498 0.675
LIG_FHA_2 71 77 PF00498 0.591
LIG_LIR_Apic_2 55 61 PF02991 0.474
LIG_LIR_Nem_3 12 18 PF02991 0.535
LIG_LIR_Nem_3 244 250 PF02991 0.514
LIG_LIR_Nem_3 269 273 PF02991 0.513
LIG_LIR_Nem_3 56 62 PF02991 0.473
LIG_Pex14_2 250 254 PF04695 0.576
LIG_Pex14_2 58 62 PF04695 0.472
LIG_SH2_CRK 15 19 PF00017 0.562
LIG_SH2_STAT5 122 125 PF00017 0.526
LIG_SH2_STAT5 15 18 PF00017 0.562
LIG_SH3_3 71 77 PF00018 0.607
LIG_SH3_3 88 94 PF00018 0.478
LIG_WRC_WIRS_1 181 186 PF05994 0.561
MOD_CDK_SPxxK_3 106 113 PF00069 0.539
MOD_CK1_1 121 127 PF00069 0.582
MOD_CK1_1 159 165 PF00069 0.638
MOD_CK1_1 20 26 PF00069 0.534
MOD_CK1_1 274 280 PF00069 0.537
MOD_CK1_1 48 54 PF00069 0.511
MOD_CK1_1 80 86 PF00069 0.531
MOD_CK2_1 106 112 PF00069 0.635
MOD_CK2_1 226 232 PF00069 0.676
MOD_GlcNHglycan 19 22 PF01048 0.570
MOD_GlcNHglycan 234 237 PF01048 0.715
MOD_GlcNHglycan 273 276 PF01048 0.561
MOD_GlcNHglycan 292 295 PF01048 0.537
MOD_GlcNHglycan 7 10 PF01048 0.576
MOD_GSK3_1 102 109 PF00069 0.664
MOD_GSK3_1 127 134 PF00069 0.475
MOD_GSK3_1 13 20 PF00069 0.526
MOD_GSK3_1 153 160 PF00069 0.708
MOD_GSK3_1 22 29 PF00069 0.518
MOD_GSK3_1 48 55 PF00069 0.528
MOD_GSK3_1 5 12 PF00069 0.511
MOD_GSK3_1 65 72 PF00069 0.464
MOD_GSK3_1 78 85 PF00069 0.533
MOD_N-GLC_1 127 132 PF02516 0.532
MOD_NEK2_1 163 168 PF00069 0.671
MOD_NEK2_1 64 69 PF00069 0.488
MOD_NEK2_1 82 87 PF00069 0.492
MOD_PKA_1 118 124 PF00069 0.584
MOD_PKA_1 241 247 PF00069 0.395
MOD_PKA_2 179 185 PF00069 0.555
MOD_PKA_2 232 238 PF00069 0.641
MOD_PKA_2 241 247 PF00069 0.440
MOD_PKA_2 271 277 PF00069 0.521
MOD_PKA_2 45 51 PF00069 0.479
MOD_PKA_2 5 11 PF00069 0.579
MOD_PKA_2 83 89 PF00069 0.529
MOD_Plk_1 111 117 PF00069 0.535
MOD_Plk_1 52 58 PF00069 0.569
MOD_Plk_2-3 135 141 PF00069 0.375
MOD_Plk_4 118 124 PF00069 0.602
MOD_Plk_4 140 146 PF00069 0.586
MOD_Plk_4 164 170 PF00069 0.533
MOD_Plk_4 53 59 PF00069 0.530
MOD_ProDKin_1 106 112 PF00069 0.582
MOD_ProDKin_1 157 163 PF00069 0.638
MOD_ProDKin_1 22 28 PF00069 0.519
MOD_ProDKin_1 70 76 PF00069 0.643
MOD_ProDKin_1 87 93 PF00069 0.495
MOD_ProDKin_1 9 15 PF00069 0.513
MOD_SUMO_for_1 236 239 PF00179 0.504
MOD_SUMO_rev_2 134 144 PF00179 0.535
MOD_SUMO_rev_2 235 243 PF00179 0.487
MOD_SUMO_rev_2 274 280 PF00179 0.448
TRG_DiLeu_BaEn_1 282 287 PF01217 0.472
TRG_DiLeu_BaLyEn_6 60 65 PF01217 0.467
TRG_DiLeu_BaLyEn_6 88 93 PF01217 0.618
TRG_ENDOCYTIC_2 15 18 PF00928 0.562
TRG_ENDOCYTIC_2 247 250 PF00928 0.534
TRG_ER_diArg_1 115 117 PF00400 0.707
TRG_ER_diArg_1 45 47 PF00400 0.475
TRG_NLS_MonoExtN_4 116 121 PF00514 0.638

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IBI0 Leishmania donovani 65% 100%
Q4QD25 Leishmania major 63% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS