LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
E9AI62_LEIBR
TriTrypDb:
LbrM.19.1541 , LBRM2903_190021700 *
Length:
124

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AI62
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AI62

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 29 31 PF00675 0.626
CLV_NRD_NRD_1 4 6 PF00675 0.542
CLV_PCSK_KEX2_1 29 31 PF00082 0.626
CLV_PCSK_KEX2_1 4 6 PF00082 0.542
CLV_PCSK_SKI1_1 112 116 PF00082 0.499
CLV_PCSK_SKI1_1 120 124 PF00082 0.444
CLV_PCSK_SKI1_1 4 8 PF00082 0.536
CLV_PCSK_SKI1_1 45 49 PF00082 0.436
DEG_Nend_Nbox_1 1 3 PF02207 0.564
DOC_PP1_RVXF_1 110 117 PF00149 0.672
DOC_WW_Pin1_4 105 110 PF00397 0.703
DOC_WW_Pin1_4 33 38 PF00397 0.428
DOC_WW_Pin1_4 69 74 PF00397 0.496
LIG_14-3-3_CanoR_1 29 33 PF00244 0.628
LIG_14-3-3_CanoR_1 5 11 PF00244 0.506
LIG_14-3-3_CanoR_1 59 65 PF00244 0.655
LIG_FHA_1 42 48 PF00498 0.497
LIG_FHA_1 94 100 PF00498 0.674
LIG_LIR_Nem_3 34 38 PF02991 0.422
LIG_PDZ_Class_2 119 124 PF00595 0.460
LIG_WRC_WIRS_1 32 37 PF05994 0.417
MOD_CDK_SPxxK_3 105 112 PF00069 0.480
MOD_CDK_SPxxK_3 69 76 PF00069 0.494
MOD_CK1_1 108 114 PF00069 0.677
MOD_CK1_1 60 66 PF00069 0.573
MOD_Cter_Amidation 2 5 PF01082 0.553
MOD_GlcNHglycan 49 52 PF01048 0.580
MOD_GlcNHglycan 60 63 PF01048 0.526
MOD_GlcNHglycan 78 81 PF01048 0.642
MOD_GlcNHglycan 8 11 PF01048 0.492
MOD_GSK3_1 104 111 PF00069 0.714
MOD_GSK3_1 43 50 PF00069 0.594
MOD_LATS_1 110 116 PF00433 0.498
MOD_N-GLC_1 23 28 PF02516 0.397
MOD_NEK2_1 104 109 PF00069 0.707
MOD_NEK2_1 57 62 PF00069 0.594
MOD_NEK2_1 94 99 PF00069 0.560
MOD_NEK2_2 43 48 PF00069 0.443
MOD_PIKK_1 23 29 PF00454 0.505
MOD_PKA_2 28 34 PF00069 0.422
MOD_PKA_2 58 64 PF00069 0.643
MOD_PKA_2 94 100 PF00069 0.431
MOD_Plk_4 94 100 PF00069 0.431
MOD_ProDKin_1 105 111 PF00069 0.704
MOD_ProDKin_1 33 39 PF00069 0.430
MOD_ProDKin_1 69 75 PF00069 0.495
MOD_SUMO_rev_2 68 78 PF00179 0.683
TRG_ER_diArg_1 4 6 PF00400 0.531
TRG_ER_diLys_1 119 124 PF00400 0.460

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3I1 Leptomonas seymouri 46% 100%
A0A0N0P7U0 Leptomonas seymouri 68% 100%
A0A0S4J296 Bodo saltans 34% 100%
A0A3Q8IBH0 Leishmania donovani 78% 100%
D0A0T6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 40% 98%
E9AHU8 Leishmania infantum 78% 100%
E9AS83 Leishmania mexicana (strain MHOM/GT/2001/U1103) 76% 100%
Q4QD83 Leishmania major 77% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS