LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
E9AI51_LEIBR
TriTrypDb:
LbrM.15.1421 , LBRM2903_150021400
Length:
95

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AI51
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AI51

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 65 67 PF00675 0.482
CLV_NRD_NRD_1 69 71 PF00675 0.494
CLV_PCSK_KEX2_1 65 67 PF00082 0.482
CLV_PCSK_KEX2_1 69 71 PF00082 0.494
CLV_PCSK_PC7_1 65 71 PF00082 0.377
CLV_PCSK_SKI1_1 77 81 PF00082 0.513
DOC_CKS1_1 2 7 PF01111 0.597
DOC_MAPK_gen_1 65 75 PF00069 0.378
DOC_USP7_MATH_1 11 15 PF00917 0.801
DOC_WW_Pin1_4 1 6 PF00397 0.635
LIG_14-3-3_CanoR_1 46 53 PF00244 0.524
LIG_eIF4E_1 52 58 PF01652 0.395
LIG_FHA_1 17 23 PF00498 0.674
LIG_FHA_2 2 8 PF00498 0.679
LIG_LIR_Nem_3 76 82 PF02991 0.485
LIG_SH2_STAT5 52 55 PF00017 0.402
LIG_TRAF2_1 36 39 PF00917 0.487
MOD_CK1_1 34 40 PF00069 0.548
MOD_CK2_1 11 17 PF00069 0.690
MOD_GSK3_1 18 25 PF00069 0.639
MOD_GSK3_1 34 41 PF00069 0.583
MOD_LATS_1 44 50 PF00433 0.460
MOD_N-GLC_1 31 36 PF02516 0.523
MOD_PIKK_1 34 40 PF00454 0.498
MOD_PKA_2 45 51 PF00069 0.533
MOD_Plk_1 31 37 PF00069 0.491
MOD_Plk_2-3 59 65 PF00069 0.399
MOD_ProDKin_1 1 7 PF00069 0.636
TRG_DiLeu_BaEn_3 55 61 PF01217 0.380
TRG_ER_diArg_1 65 67 PF00400 0.482

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I0X5 Leptomonas seymouri 35% 100%
A0A3Q8IA91 Leishmania donovani 60% 100%
A0A3R7K7I4 Trypanosoma rangeli 36% 88%
A4HWN0 Leishmania infantum 60% 100%
E9AQD8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 58% 100%
Q4QF37 Leishmania major 59% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS