Sel1 repeat-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

E9AI29_LEIBR

TriTrypDb:

LbrM.07.1100 , LBRM2903_070020100

Length:

443

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AI29

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AI29

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	208	210	PF00675	0.644
CLV_NRD_NRD_1	38	40	PF00675	0.615
CLV_NRD_NRD_1	41	43	PF00675	0.605
CLV_NRD_NRD_1	6	8	PF00675	0.574
CLV_PCSK_FUR_1	39	43	PF00082	0.580
CLV_PCSK_KEX2_1	208	210	PF00082	0.657
CLV_PCSK_KEX2_1	38	40	PF00082	0.615
CLV_PCSK_KEX2_1	41	43	PF00082	0.605
CLV_PCSK_KEX2_1	420	422	PF00082	0.424
CLV_PCSK_KEX2_1	6	8	PF00082	0.574
CLV_PCSK_PC1ET2_1	420	422	PF00082	0.428
CLV_PCSK_SKI1_1	31	35	PF00082	0.576
CLV_PCSK_SKI1_1	392	396	PF00082	0.437
CLV_PCSK_SKI1_1	65	69	PF00082	0.590
DEG_SPOP_SBC_1	147	151	PF00917	0.563
DOC_CKS1_1	179	184	PF01111	0.377
DOC_CKS1_1	57	62	PF01111	0.549
DOC_CYCLIN_yCln2_LP_2	257	263	PF00134	0.489
DOC_PP4_FxxP_1	101	104	PF00568	0.503
DOC_PP4_FxxP_1	86	89	PF00568	0.444
DOC_USP7_MATH_1	131	135	PF00917	0.705
DOC_USP7_MATH_1	251	255	PF00917	0.578
DOC_USP7_MATH_1	302	306	PF00917	0.497
DOC_USP7_MATH_1	321	325	PF00917	0.285
DOC_USP7_MATH_1	352	356	PF00917	0.609
DOC_USP7_MATH_1	5	9	PF00917	0.568
DOC_USP7_MATH_1	63	67	PF00917	0.561
DOC_USP7_MATH_1	94	98	PF00917	0.581
DOC_WW_Pin1_4	105	110	PF00397	0.572
DOC_WW_Pin1_4	134	139	PF00397	0.706
DOC_WW_Pin1_4	178	183	PF00397	0.386
DOC_WW_Pin1_4	231	236	PF00397	0.367
DOC_WW_Pin1_4	256	261	PF00397	0.491
DOC_WW_Pin1_4	32	37	PF00397	0.602
DOC_WW_Pin1_4	56	61	PF00397	0.624
LIG_14-3-3_CanoR_1	209	215	PF00244	0.565
LIG_14-3-3_CanoR_1	31	36	PF00244	0.602
LIG_14-3-3_CanoR_1	329	338	PF00244	0.515
LIG_14-3-3_CanoR_1	7	13	PF00244	0.575
LIG_BRCT_BRCA1_1	157	161	PF00533	0.630
LIG_CtBP_PxDLS_1	21	27	PF00389	0.573
LIG_deltaCOP1_diTrp_1	367	374	PF00928	0.461
LIG_EVH1_1	86	90	PF00568	0.446
LIG_FHA_1	312	318	PF00498	0.569
LIG_FHA_2	427	433	PF00498	0.563
LIG_FHA_2	57	63	PF00498	0.550
LIG_LIR_Apic_2	99	104	PF02991	0.556
LIG_LIR_Gen_1	289	297	PF02991	0.360
LIG_LIR_LC3C_4	270	273	PF02991	0.294
LIG_LIR_Nem_3	289	293	PF02991	0.357
LIG_LIR_Nem_3	66	70	PF02991	0.557
LIG_PCNA_PIPBox_1	387	396	PF02747	0.315
LIG_PCNA_yPIPBox_3	184	198	PF02747	0.521
LIG_SH2_SRC	336	339	PF00017	0.381
LIG_SH2_STAP1	347	351	PF00017	0.383
LIG_SH2_STAT5	336	339	PF00017	0.440
LIG_SH3_1	84	90	PF00018	0.451
LIG_SH3_2	2	7	PF14604	0.549
LIG_SH3_3	294	300	PF00018	0.509
LIG_SH3_3	54	60	PF00018	0.607
LIG_SH3_3	84	90	PF00018	0.507
LIG_SUMO_SIM_anti_2	258	266	PF11976	0.365
LIG_SUMO_SIM_anti_2	270	275	PF11976	0.313
LIG_SUMO_SIM_par_1	258	266	PF11976	0.299
LIG_WRC_WIRS_1	287	292	PF05994	0.559
MOD_CDC14_SPxK_1	35	38	PF00782	0.604
MOD_CDK_SPxK_1	32	38	PF00069	0.603
MOD_CDK_SPxxK_3	178	185	PF00069	0.390
MOD_CDK_SPxxK_3	32	39	PF00069	0.605
MOD_CK1_1	108	114	PF00069	0.494
MOD_CK1_1	134	140	PF00069	0.647
MOD_CK1_1	148	154	PF00069	0.690
MOD_CK1_1	157	163	PF00069	0.545
MOD_CK1_1	174	180	PF00069	0.333
MOD_CK1_1	213	219	PF00069	0.653
MOD_CK1_1	323	329	PF00069	0.520
MOD_CK1_1	403	409	PF00069	0.597
MOD_CK1_1	8	14	PF00069	0.573
MOD_CK1_1	96	102	PF00069	0.601
MOD_CK2_1	146	152	PF00069	0.674
MOD_CK2_1	157	163	PF00069	0.481
MOD_CK2_1	426	432	PF00069	0.493
MOD_CK2_1	56	62	PF00069	0.549
MOD_Cter_Amidation	39	42	PF01082	0.584
MOD_GlcNHglycan	127	130	PF01048	0.693
MOD_GlcNHglycan	133	136	PF01048	0.671
MOD_GlcNHglycan	173	176	PF01048	0.501
MOD_GlcNHglycan	242	245	PF01048	0.564
MOD_GlcNHglycan	252	256	PF01048	0.545
MOD_GlcNHglycan	332	335	PF01048	0.523
MOD_GlcNHglycan	404	408	PF01048	0.573
MOD_GlcNHglycan	7	10	PF01048	0.576
MOD_GlcNHglycan	81	84	PF01048	0.727
MOD_GlcNHglycan	98	101	PF01048	0.524
MOD_GSK3_1	147	154	PF00069	0.686
MOD_GSK3_1	174	181	PF00069	0.602
MOD_GSK3_1	240	247	PF00069	0.446
MOD_GSK3_1	251	258	PF00069	0.424
MOD_GSK3_1	73	80	PF00069	0.605
MOD_GSK3_1	8	15	PF00069	0.572
MOD_N-GLC_1	125	130	PF02516	0.713
MOD_NEK2_1	12	17	PF00069	0.616
MOD_NEK2_1	169	174	PF00069	0.412
MOD_NEK2_1	263	268	PF00069	0.263
MOD_NEK2_2	63	68	PF00069	0.561
MOD_PIKK_1	16	22	PF00454	0.548
MOD_PIKK_1	383	389	PF00454	0.452
MOD_PKA_1	208	214	PF00069	0.568
MOD_PKA_2	208	214	PF00069	0.568
MOD_PKA_2	5	11	PF00069	0.569
MOD_Plk_1	76	82	PF00069	0.532
MOD_Plk_1	94	100	PF00069	0.472
MOD_Plk_4	174	180	PF00069	0.602
MOD_Plk_4	286	292	PF00069	0.393
MOD_Plk_4	323	329	PF00069	0.520
MOD_ProDKin_1	105	111	PF00069	0.572
MOD_ProDKin_1	134	140	PF00069	0.705
MOD_ProDKin_1	178	184	PF00069	0.385
MOD_ProDKin_1	231	237	PF00069	0.367
MOD_ProDKin_1	256	262	PF00069	0.483
MOD_ProDKin_1	32	38	PF00069	0.603
MOD_ProDKin_1	56	62	PF00069	0.627
TRG_DiLeu_BaEn_1	433	438	PF01217	0.420
TRG_ER_diArg_1	38	41	PF00400	0.585
TRG_ER_diArg_1	5	7	PF00400	0.563
TRG_Pf-PMV_PEXEL_1	185	189	PF00026	0.500
TRG_Pf-PMV_PEXEL_1	192	196	PF00026	0.482
TRG_Pf-PMV_PEXEL_1	212	217	PF00026	0.374
TRG_Pf-PMV_PEXEL_1	356	360	PF00026	0.450

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBF0	Leptomonas seymouri	48%	97%
A0A3S7WQ08	Leishmania donovani	79%	100%
A4HTC9	Leishmania infantum	79%	100%
E9ALC2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	100%
Q4QII3	Leishmania major	81%	100%
V5BYB8	Trypanosoma cruzi	32%	100%