Putative mitochondrial carrier protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

mitochondrial carrier protein - putative

Species:

Leishmania infantum

UniProt:

E9AI04_LEIIN

TriTrypDb:

LINF_360079000

Length:

204

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

Expansion

Sequence features

E9AI04

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AI04

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	72	76	PF00082	0.398
DEG_SCF_FBW7_1	103	110	PF00400	0.519
DOC_CKS1_1	104	109	PF01111	0.521
DOC_CKS1_1	23	28	PF01111	0.190
DOC_CKS1_1	8	13	PF01111	0.562
DOC_CYCLIN_yCln2_LP_2	23	29	PF00134	0.336
DOC_MAPK_MEF2A_6	37	44	PF00069	0.386
DOC_USP7_MATH_1	107	111	PF00917	0.530
DOC_USP7_MATH_1	184	188	PF00917	0.336
DOC_WW_Pin1_4	103	108	PF00397	0.488
DOC_WW_Pin1_4	22	27	PF00397	0.204
DOC_WW_Pin1_4	7	12	PF00397	0.545
DOC_WW_Pin1_4	76	81	PF00397	0.415
LIG_14-3-3_CanoR_1	100	104	PF00244	0.415
LIG_14-3-3_CanoR_1	172	179	PF00244	0.460
LIG_BIR_II_1	1	5	PF00653	0.610
LIG_BIR_III_1	1	5	PF00653	0.610
LIG_BIR_III_3	1	5	PF00653	0.610
LIG_FHA_1	194	200	PF00498	0.416
LIG_FHA_1	22	28	PF00498	0.301
LIG_FHA_1	77	83	PF00498	0.424
LIG_FHA_1	99	105	PF00498	0.380
LIG_FHA_2	100	106	PF00498	0.415
LIG_LIR_Nem_3	168	174	PF02991	0.432
LIG_LIR_Nem_3	187	192	PF02991	0.134
LIG_LIR_Nem_3	69	74	PF02991	0.395
LIG_Pex14_1	132	136	PF04695	0.336
LIG_SH2_CRK	71	75	PF00017	0.415
LIG_SH2_STAP1	174	178	PF00017	0.415
LIG_SH2_STAT5	174	177	PF00017	0.415
LIG_SH2_STAT5	28	31	PF00017	0.336
LIG_SH2_STAT5	78	81	PF00017	0.353
LIG_SH2_STAT5	92	95	PF00017	0.301
LIG_SH3_3	114	120	PF00018	0.413
LIG_SH3_3	5	11	PF00018	0.638
LIG_SH3_3	52	58	PF00018	0.415
LIG_WRC_WIRS_1	195	200	PF05994	0.415
MOD_CK1_1	76	82	PF00069	0.415
MOD_GlcNHglycan	122	125	PF01048	0.332
MOD_GlcNHglycan	167	170	PF01048	0.409
MOD_GlcNHglycan	186	189	PF01048	0.220
MOD_GlcNHglycan	75	78	PF01048	0.374
MOD_GSK3_1	103	110	PF00069	0.406
MOD_GSK3_1	95	102	PF00069	0.363
MOD_N-GLC_1	184	189	PF02516	0.301
MOD_NEK2_1	131	136	PF00069	0.303
MOD_NEK2_1	14	19	PF00069	0.336
MOD_NEK2_1	140	145	PF00069	0.304
MOD_NEK2_1	178	183	PF00069	0.415
MOD_NEK2_1	194	199	PF00069	0.175
MOD_OFUCOSY	138	144	PF10250	0.415
MOD_PK_1	150	156	PF00069	0.415
MOD_PKA_1	150	156	PF00069	0.415
MOD_PKA_2	99	105	PF00069	0.415
MOD_Plk_1	50	56	PF00069	0.415
MOD_Plk_4	194	200	PF00069	0.358
MOD_Plk_4	78	84	PF00069	0.301
MOD_Plk_4	99	105	PF00069	0.420
MOD_ProDKin_1	103	109	PF00069	0.485
MOD_ProDKin_1	22	28	PF00069	0.204
MOD_ProDKin_1	7	13	PF00069	0.535
MOD_ProDKin_1	76	82	PF00069	0.415
TRG_ENDOCYTIC_2	71	74	PF00928	0.409
TRG_NES_CRM1_1	22	36	PF08389	0.386

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0G2K309	Rattus norvegicus	28%	68%
A0A0N0P7X0	Leptomonas seymouri	29%	67%
A0A0N0P7Y4	Leptomonas seymouri	29%	70%
A0A0S4IV98	Bodo saltans	28%	75%
A0A0S4JM95	Bodo saltans	29%	68%
A0A1X0NFT4	Trypanosomatidae	30%	68%
A0A1X0NJD2	Trypanosomatidae	28%	72%
A0A1X0NLW7	Trypanosomatidae	49%	68%
A0A3Q8ILJ6	Leishmania donovani	100%	100%
A0A3R7RT89	Trypanosoma rangeli	28%	70%
A0A3S7WTS6	Leishmania donovani	28%	68%
A0A3S7WYS1	Leishmania donovani	27%	67%
A0A422NDP6	Trypanosoma rangeli	30%	89%
A0A422NVT9	Trypanosoma rangeli	45%	68%
A4H8E6	Leishmania braziliensis	27%	68%
A4HDW8	Leishmania braziliensis	28%	67%
A4HWR9	Leishmania infantum	29%	68%
A4I163	Leishmania infantum	27%	67%
A4QNX2	Danio rerio	28%	71%
C9ZW54	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	67%
D0A728	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	81%
E9AQH7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	68%
E9AX97	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	67%
O43772	Homo sapiens	27%	68%
P32331	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	66%
P97521	Rattus norvegicus	28%	68%
Q08DK7	Bos taurus	30%	68%
Q10248	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	30%	68%
Q12375	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	70%
Q1ECW7	Danio rerio	27%	69%
Q4QA75	Leishmania major	26%	67%
Q4QF00	Leishmania major	27%	68%
Q54BM3	Dictyostelium discoideum	31%	68%
Q54FE6	Dictyostelium discoideum	29%	72%
Q54W11	Dictyostelium discoideum	26%	72%
Q55GE2	Dictyostelium discoideum	29%	68%
Q5HZE0	Rattus norvegicus	31%	67%
Q6DHS9	Danio rerio	26%	66%
Q86AV5	Dictyostelium discoideum	25%	68%
Q8BL03	Mus musculus	31%	67%
Q8BW66	Mus musculus	30%	67%
Q8CFJ7	Mus musculus	26%	71%
Q8HXY2	Macaca fascicularis	28%	68%
Q8N413	Homo sapiens	28%	71%
Q8N8R3	Homo sapiens	30%	67%
Q93XM7	Arabidopsis thaliana	29%	68%
Q9BXI2	Homo sapiens	29%	68%
Q9CA93	Arabidopsis thaliana	26%	69%
Q9M038	Arabidopsis thaliana	29%	66%
Q9VM51	Drosophila melanogaster	26%	68%
Q9VQG4	Drosophila melanogaster	31%	67%
Q9WVD5	Mus musculus	27%	68%
Q9Y619	Homo sapiens	28%	68%
Q9Z2Z6	Mus musculus	27%	68%
Q9ZWG1	Arabidopsis thaliana	25%	67%
V5BD15	Trypanosoma cruzi	44%	68%
V5BDR1	Trypanosoma cruzi	30%	69%
V5BVW0	Trypanosoma cruzi	29%	70%