Uncharacterized protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AHZ0_LEIIN

TriTrypDb:

LINF_360077500

Length:

193

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	3
GO:0110165	cellular anatomical entity	1	3

Expansion

Sequence features

E9AHZ0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHZ0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	165	169	PF00082	0.386
CLV_PCSK_SKI1_1	61	65	PF00082	0.529
DOC_AGCK_PIF_2	41	46	PF00069	0.636
DOC_WW_Pin1_4	82	87	PF00397	0.495
LIG_14-3-3_CanoR_1	114	118	PF00244	0.337
LIG_Actin_WH2_2	94	109	PF00022	0.550
LIG_BIR_II_1	1	5	PF00653	0.746
LIG_FHA_1	101	107	PF00498	0.483
LIG_FHA_1	129	135	PF00498	0.448
LIG_FHA_1	173	179	PF00498	0.669
LIG_FHA_1	28	34	PF00498	0.695
LIG_FHA_1	83	89	PF00498	0.495
LIG_LIR_Gen_1	116	126	PF02991	0.157
LIG_LIR_Gen_1	96	105	PF02991	0.470
LIG_LIR_Nem_3	116	121	PF02991	0.186
LIG_LIR_Nem_3	38	44	PF02991	0.632
LIG_LIR_Nem_3	96	100	PF02991	0.470
LIG_Pex14_2	117	121	PF04695	0.460
LIG_Pex14_2	140	144	PF04695	0.595
LIG_Pex14_2	37	41	PF04695	0.629
LIG_Pex14_2	93	97	PF04695	0.363
LIG_PTB_Apo_2	96	103	PF02174	0.351
LIG_PTB_Phospho_1	96	102	PF10480	0.351
LIG_SH2_CRK	102	106	PF00017	0.491
LIG_SH2_STAP1	102	106	PF00017	0.378
LIG_SH2_STAP1	169	173	PF00017	0.610
LIG_SH2_STAT5	102	105	PF00017	0.386
LIG_SH2_STAT5	139	142	PF00017	0.595
LIG_SH3_3	171	177	PF00018	0.615
LIG_SH3_3	59	65	PF00018	0.709
LIG_SUMO_SIM_par_1	29	34	PF11976	0.694
LIG_SUMO_SIM_par_1	85	91	PF11976	0.351
MOD_CK1_1	116	122	PF00069	0.437
MOD_CK1_1	2	8	PF00069	0.789
MOD_CK1_1	27	33	PF00069	0.606
MOD_CK2_1	148	154	PF00069	0.609
MOD_CMANNOS	115	118	PF00535	0.432
MOD_GlcNHglycan	1	4	PF01048	0.547
MOD_GSK3_1	109	116	PF00069	0.382
MOD_GSK3_1	73	80	PF00069	0.705
MOD_N-GLC_1	106	111	PF02516	0.602
MOD_N-GLC_1	128	133	PF02516	0.442
MOD_NEK2_1	100	105	PF00069	0.415
MOD_NEK2_1	106	111	PF00069	0.314
MOD_NEK2_1	88	93	PF00069	0.389
MOD_PKA_2	113	119	PF00069	0.351
MOD_Plk_4	27	33	PF00069	0.691
MOD_Plk_4	88	94	PF00069	0.432
MOD_ProDKin_1	82	88	PF00069	0.495
MOD_SUMO_for_1	63	66	PF00179	0.740
TRG_DiLeu_BaLyEn_6	101	106	PF01217	0.498
TRG_ENDOCYTIC_2	102	105	PF00928	0.386

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8C4	Leptomonas seymouri	81%	100%
A0A1X0NM34	Trypanosomatidae	71%	100%
A0A3Q8II68	Leishmania donovani	100%	100%
D0A3M8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	71%	100%
E9AU94	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
Q4Q097	Leishmania major	97%	100%