Secreted protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Secreted protein

Gene product:

hypothetical protein

Species:

Leishmania infantum

UniProt:

E9AHX2_LEIIN

TriTrypDb:

LINF_360018500

Length:

114

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

E9AHX2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHX2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	67	69	PF00675	0.380
CLV_NRD_NRD_1	83	85	PF00675	0.410
CLV_PCSK_KEX2_1	67	69	PF00082	0.380
CLV_PCSK_KEX2_1	85	87	PF00082	0.406
CLV_PCSK_PC1ET2_1	85	87	PF00082	0.406
DEG_Nend_UBRbox_2	1	3	PF02207	0.640
DOC_AGCK_PIF_1	44	49	PF00069	0.243
DOC_CDC14_PxL_1	3	11	PF14671	0.566
DOC_MAPK_FxFP_2	47	50	PF00069	0.265
DOC_MAPK_gen_1	84	93	PF00069	0.604
DOC_PP1_RVXF_1	88	94	PF00149	0.648
DOC_PP2B_LxvP_1	4	7	PF13499	0.571
DOC_PP4_FxxP_1	47	50	PF00568	0.265
LIG_14-3-3_CanoR_1	10	15	PF00244	0.446
LIG_BRCT_BRCA1_1	47	51	PF00533	0.261
LIG_FHA_1	36	42	PF00498	0.384
LIG_LIR_Apic_2	45	50	PF02991	0.264
LIG_LIR_Gen_1	13	22	PF02991	0.391
LIG_LIR_Gen_1	94	102	PF02991	0.650
LIG_LIR_Nem_3	13	17	PF02991	0.397
LIG_LIR_Nem_3	20	26	PF02991	0.413
LIG_LIR_Nem_3	45	49	PF02991	0.484
LIG_LIR_Nem_3	94	100	PF02991	0.649
LIG_Pex14_1	43	47	PF04695	0.243
LIG_Pex14_2	47	51	PF04695	0.312
LIG_Pex14_2	52	56	PF04695	0.316
LIG_SH2_CRK	14	18	PF00017	0.392
LIG_SH2_NCK_1	14	18	PF00017	0.265
LIG_SH2_PTP2	18	21	PF00017	0.366
LIG_SH2_PTP2	23	26	PF00017	0.400
LIG_SH2_SRC	18	21	PF00017	0.331
LIG_SH2_SRC	23	26	PF00017	0.225
LIG_SH2_STAP1	14	18	PF00017	0.265
LIG_SH2_STAT5	12	15	PF00017	0.311
LIG_SH2_STAT5	18	21	PF00017	0.346
LIG_SH2_STAT5	23	26	PF00017	0.400
LIG_SH2_STAT5	97	100	PF00017	0.652
LIG_SUMO_SIM_par_1	2	8	PF11976	0.573
LIG_TYR_ITIM	21	26	PF00017	0.243
MOD_CK1_1	45	51	PF00069	0.407
MOD_CK1_1	5	11	PF00069	0.608
MOD_CK1_1	66	72	PF00069	0.622
MOD_GSK3_1	63	70	PF00069	0.637
MOD_GSK3_1	92	99	PF00069	0.772
MOD_N-GLC_1	106	111	PF02516	0.432
MOD_NEK2_1	55	60	PF00069	0.338
MOD_NEK2_1	91	96	PF00069	0.769
MOD_NEK2_2	42	47	PF00069	0.322
MOD_NEK2_2	92	97	PF00069	0.648
MOD_PIKK_1	106	112	PF00454	0.635
MOD_PKA_1	67	73	PF00069	0.586
MOD_PKA_1	86	92	PF00069	0.602
MOD_PKA_2	66	72	PF00069	0.665
MOD_PKB_1	84	92	PF00069	0.605
MOD_Plk_4	13	19	PF00069	0.453
MOD_Plk_4	92	98	PF00069	0.649
TRG_ENDOCYTIC_2	14	17	PF00928	0.392
TRG_ENDOCYTIC_2	18	21	PF00928	0.401
TRG_ENDOCYTIC_2	23	26	PF00928	0.313
TRG_ENDOCYTIC_2	97	100	PF00928	0.661

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IKD2	Leishmania donovani	74%	97%
E9AG14	Leishmania major	40%	85%