LeishMANIAdb
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Flagellar associated protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Flagellar associated protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
E9AHV3_LEIIN
TriTrypDb:
LINF_350026400
Length:
269

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AHV3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHV3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 60 64 PF00656 0.682
CLV_PCSK_KEX2_1 243 245 PF00082 0.520
CLV_PCSK_PC1ET2_1 243 245 PF00082 0.520
CLV_PCSK_SKI1_1 243 247 PF00082 0.545
DOC_PP2B_LxvP_1 251 254 PF13499 0.719
DOC_USP7_MATH_1 100 104 PF00917 0.754
DOC_USP7_MATH_1 114 118 PF00917 0.596
DOC_USP7_MATH_1 141 145 PF00917 0.667
DOC_USP7_MATH_1 168 172 PF00917 0.667
DOC_USP7_MATH_1 193 197 PF00917 0.794
DOC_WW_Pin1_4 108 113 PF00397 0.720
DOC_WW_Pin1_4 134 139 PF00397 0.816
DOC_WW_Pin1_4 146 151 PF00397 0.588
DOC_WW_Pin1_4 163 168 PF00397 0.547
LIG_14-3-3_CanoR_1 179 185 PF00244 0.728
LIG_BIR_II_1 1 5 PF00653 0.810
LIG_BIR_III_2 20 24 PF00653 0.712
LIG_BRCT_BRCA1_1 103 107 PF00533 0.839
LIG_EVH1_2 157 161 PF00568 0.759
LIG_FHA_1 206 212 PF00498 0.780
LIG_FHA_2 130 136 PF00498 0.707
LIG_FHA_2 172 178 PF00498 0.716
LIG_FHA_2 3 9 PF00498 0.733
LIG_LIR_Nem_3 125 130 PF02991 0.763
LIG_SH2_CRK 249 253 PF00017 0.724
LIG_SH2_STAP1 249 253 PF00017 0.627
LIG_SH3_3 133 139 PF00018 0.804
LIG_SH3_3 154 160 PF00018 0.726
LIG_TRAF2_1 174 177 PF00917 0.836
LIG_TRAF2_1 25 28 PF00917 0.736
LIG_TRAF2_1 67 70 PF00917 0.766
MOD_CK1_1 103 109 PF00069 0.763
MOD_CK1_1 122 128 PF00069 0.571
MOD_CK1_1 162 168 PF00069 0.694
MOD_CK1_1 171 177 PF00069 0.745
MOD_CK1_1 2 8 PF00069 0.733
MOD_CK1_1 52 58 PF00069 0.824
MOD_CK2_1 129 135 PF00069 0.706
MOD_CK2_1 171 177 PF00069 0.826
MOD_CK2_1 22 28 PF00069 0.707
MOD_CK2_1 222 228 PF00069 0.757
MOD_GlcNHglycan 103 106 PF01048 0.687
MOD_GlcNHglycan 112 115 PF01048 0.693
MOD_GlcNHglycan 121 124 PF01048 0.522
MOD_GlcNHglycan 161 164 PF01048 0.710
MOD_GlcNHglycan 24 27 PF01048 0.657
MOD_GlcNHglycan 54 58 PF01048 0.639
MOD_GlcNHglycan 83 86 PF01048 0.733
MOD_GSK3_1 103 110 PF00069 0.715
MOD_GSK3_1 130 137 PF00069 0.673
MOD_GSK3_1 159 166 PF00069 0.679
MOD_GSK3_1 180 187 PF00069 0.753
MOD_GSK3_1 189 196 PF00069 0.663
MOD_GSK3_1 22 29 PF00069 0.697
MOD_GSK3_1 45 52 PF00069 0.770
MOD_NEK2_1 1 6 PF00069 0.738
MOD_NEK2_1 107 112 PF00069 0.620
MOD_NEK2_1 204 209 PF00069 0.701
MOD_NEK2_1 216 221 PF00069 0.523
MOD_PIKK_1 197 203 PF00454 0.722
MOD_PKA_2 49 55 PF00069 0.827
MOD_Plk_1 216 222 PF00069 0.738
MOD_Plk_4 141 147 PF00069 0.747
MOD_ProDKin_1 108 114 PF00069 0.721
MOD_ProDKin_1 134 140 PF00069 0.810
MOD_ProDKin_1 146 152 PF00069 0.588
MOD_ProDKin_1 163 169 PF00069 0.551
MOD_SUMO_for_1 91 94 PF00179 0.769
MOD_SUMO_rev_2 237 245 PF00179 0.561
MOD_SUMO_rev_2 59 67 PF00179 0.608
MOD_SUMO_rev_2 84 93 PF00179 0.825
TRG_ENDOCYTIC_2 249 252 PF00928 0.604
TRG_Pf-PMV_PEXEL_1 218 222 PF00026 0.740

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IPH3 Leishmania donovani 99% 100%
A4HMN4 Leishmania braziliensis 66% 100%
E9AF36 Leishmania major 85% 100%
E9B691 Leishmania mexicana (strain MHOM/GT/2001/U1103) 76% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS