Homologous to animal VAMP7 proteins. Likely involved in vesicular transport.. Localization: Vesicular (by homology)
Vesicle mediated transport, vesicle-associated membrane
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | yes | yes: 25 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | yes | yes: 16 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 10 |
| NetGPI | no | yes: 0, no: 10 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0016020 | membrane | 2 | 11 |
| GO:0110165 | cellular anatomical entity | 1 | 11 |
| GO:0005654 | nucleoplasm | 2 | 1 |
| GO:0005737 | cytoplasm | 2 | 1 |
| GO:0005794 | Golgi apparatus | 5 | 1 |
| GO:0043226 | organelle | 2 | 1 |
| GO:0043227 | membrane-bounded organelle | 3 | 1 |
| GO:0043229 | intracellular organelle | 3 | 1 |
| GO:0043231 | intracellular membrane-bounded organelle | 4 | 1 |
Related structures:
AlphaFold database: E9AHV2
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006810 | transport | 3 | 2 |
| GO:0006888 | endoplasmic reticulum to Golgi vesicle-mediated transport | 4 | 1 |
| GO:0009987 | cellular process | 1 | 1 |
| GO:0016192 | vesicle-mediated transport | 4 | 2 |
| GO:0046907 | intracellular transport | 3 | 1 |
| GO:0048193 | Golgi vesicle transport | 5 | 1 |
| GO:0051179 | localization | 1 | 2 |
| GO:0051234 | establishment of localization | 2 | 2 |
| GO:0051641 | cellular localization | 2 | 1 |
| GO:0051649 | establishment of localization in cell | 3 | 1 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005484 | SNAP receptor activity | 3 | 1 |
| GO:0030674 | protein-macromolecule adaptor activity | 2 | 1 |
| GO:0060090 | molecular adaptor activity | 1 | 1 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_PCSK_FUR_1 | 147 | 151 | PF00082 | 0.450 |
| CLV_PCSK_KEX2_1 | 149 | 151 | PF00082 | 0.358 |
| CLV_PCSK_KEX2_1 | 53 | 55 | PF00082 | 0.363 |
| CLV_PCSK_PC1ET2_1 | 149 | 151 | PF00082 | 0.358 |
| CLV_PCSK_PC1ET2_1 | 53 | 55 | PF00082 | 0.359 |
| CLV_PCSK_PC7_1 | 49 | 55 | PF00082 | 0.381 |
| CLV_PCSK_SKI1_1 | 54 | 58 | PF00082 | 0.385 |
| CLV_PCSK_SKI1_1 | 92 | 96 | PF00082 | 0.338 |
| DEG_Nend_UBRbox_1 | 1 | 4 | PF02207 | 0.378 |
| DOC_PP1_RVXF_1 | 90 | 96 | PF00149 | 0.338 |
| LIG_14-3-3_CanoR_1 | 37 | 45 | PF00244 | 0.402 |
| LIG_14-3-3_CanoR_1 | 92 | 98 | PF00244 | 0.338 |
| LIG_BRCT_BRCA1_1 | 186 | 190 | PF00533 | 0.338 |
| LIG_BRCT_BRCA1_1 | 30 | 34 | PF00533 | 0.418 |
| LIG_FHA_1 | 153 | 159 | PF00498 | 0.338 |
| LIG_GBD_Chelix_1 | 93 | 101 | PF00786 | 0.358 |
| LIG_LIR_Apic_2 | 134 | 139 | PF02991 | 0.488 |
| LIG_LIR_Gen_1 | 42 | 51 | PF02991 | 0.363 |
| LIG_LIR_Nem_3 | 30 | 35 | PF02991 | 0.425 |
| LIG_LIR_Nem_3 | 42 | 46 | PF02991 | 0.367 |
| LIG_NRBOX | 2 | 8 | PF00104 | 0.468 |
| LIG_Pex14_2 | 105 | 109 | PF04695 | 0.322 |
| LIG_REV1ctd_RIR_1 | 32 | 41 | PF16727 | 0.409 |
| LIG_SH2_CRK | 4 | 8 | PF00017 | 0.464 |
| LIG_SH2_NCK_1 | 113 | 117 | PF00017 | 0.452 |
| LIG_SH2_NCK_1 | 160 | 164 | PF00017 | 0.338 |
| LIG_SH2_NCK_1 | 71 | 75 | PF00017 | 0.405 |
| LIG_SH2_SRC | 71 | 74 | PF00017 | 0.450 |
| LIG_SH2_STAT5 | 191 | 194 | PF00017 | 0.411 |
| LIG_SH3_3 | 8 | 14 | PF00018 | 0.464 |
| LIG_TYR_ITIM | 158 | 163 | PF00017 | 0.338 |
| LIG_UBA3_1 | 145 | 149 | PF00899 | 0.338 |
| LIG_UBA3_1 | 6 | 10 | PF00899 | 0.467 |
| LIG_WRC_WIRS_1 | 29 | 34 | PF05994 | 0.408 |
| MOD_CAAXbox | 202 | 205 | PF01239 | 0.601 |
| MOD_CK2_1 | 36 | 42 | PF00069 | 0.413 |
| MOD_CK2_1 | 82 | 88 | PF00069 | 0.381 |
| MOD_GlcNHglycan | 198 | 201 | PF01048 | 0.528 |
| MOD_GlcNHglycan | 24 | 27 | PF01048 | 0.385 |
| MOD_GlcNHglycan | 38 | 41 | PF01048 | 0.334 |
| MOD_N-GLC_1 | 129 | 134 | PF02516 | 0.515 |
| MOD_NEK2_1 | 105 | 110 | PF00069 | 0.338 |
| MOD_NEK2_1 | 35 | 40 | PF00069 | 0.442 |
| MOD_NEK2_1 | 47 | 52 | PF00069 | 0.283 |
| MOD_NEK2_2 | 186 | 191 | PF00069 | 0.338 |
| MOD_PIKK_1 | 189 | 195 | PF00454 | 0.411 |
| MOD_PIKK_1 | 58 | 64 | PF00454 | 0.358 |
| MOD_PK_1 | 112 | 118 | PF00069 | 0.555 |
| MOD_PKA_2 | 36 | 42 | PF00069 | 0.413 |
| MOD_Plk_1 | 129 | 135 | PF00069 | 0.438 |
| MOD_Plk_1 | 27 | 33 | PF00069 | 0.393 |
| MOD_Plk_4 | 186 | 192 | PF00069 | 0.338 |
| MOD_SUMO_rev_2 | 151 | 158 | PF00179 | 0.338 |
| TRG_DiLeu_BaEn_2 | 41 | 47 | PF01217 | 0.375 |
| TRG_DiLeu_BaEn_3 | 140 | 146 | PF01217 | 0.358 |
| TRG_ENDOCYTIC_2 | 113 | 116 | PF00928 | 0.444 |
| TRG_ENDOCYTIC_2 | 160 | 163 | PF00928 | 0.338 |
| TRG_ENDOCYTIC_2 | 4 | 7 | PF00928 | 0.426 |
| TRG_Pf-PMV_PEXEL_1 | 150 | 154 | PF00026 | 0.358 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P2C0 | Leptomonas seymouri | 92% | 100% |
| A0A0S4J646 | Bodo saltans | 61% | 100% |
| A0A0S4JCC4 | Bodo saltans | 25% | 88% |
| A0A1X0P617 | Trypanosomatidae | 80% | 100% |
| A0A3R7M993 | Trypanosoma rangeli | 80% | 100% |
| A0A3S7X9G1 | Leishmania donovani | 100% | 100% |
| A4HMN3 | Leishmania braziliensis | 94% | 100% |
| C9ZZF4 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 81% | 100% |
| D0A159 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 26% | 86% |
| E9AF35 | Leishmania major | 98% | 100% |
| E9B690 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 98% | 100% |
| O15498 | Homo sapiens | 38% | 100% |
| O60073 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 38% | 100% |
| P36015 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 33% | 100% |
| P51809 | Homo sapiens | 23% | 93% |
| P70280 | Mus musculus | 23% | 93% |
| Q17QI5 | Bos taurus | 23% | 93% |
| Q32N70 | Xenopus laevis | 36% | 100% |
| Q3T000 | Bos taurus | 37% | 100% |
| Q54ES8 | Dictyostelium discoideum | 33% | 100% |
| Q5EGY4 | Rattus norvegicus | 38% | 100% |
| Q5RF94 | Pongo abelii | 23% | 93% |
| Q5ZL74 | Gallus gallus | 22% | 93% |
| Q6BSL0 | Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) | 32% | 100% |
| Q6C537 | Yarrowia lipolytica (strain CLIB 122 / E 150) | 35% | 100% |
| Q6CSA2 | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) | 34% | 100% |
| Q6DDU7 | Xenopus laevis | 36% | 100% |
| Q6FW27 | Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) | 30% | 100% |
| Q6P816 | Xenopus tropicalis | 36% | 100% |
| Q757A4 | Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) | 33% | 100% |
| Q7ZUN8 | Danio rerio | 35% | 100% |
| Q9CQW1 | Mus musculus | 38% | 100% |
| Q9JHW5 | Rattus norvegicus | 22% | 93% |
| Q9LVM9 | Arabidopsis thaliana | 38% | 100% |
| Q9ZRD6 | Arabidopsis thaliana | 43% | 100% |