LeishMANIAdb
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Kinesin motor domain-containing protein

Quick info Annotations Function or PPIs Localization Abundance Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Kinesin motor domain-containing protein
Gene product:
flagellar attachment zone protein - putative
Species:
Leishmania infantum
UniProt:
E9AHT7_LEIIN
TriTrypDb:
LINF_340031200
Length:
854

Annotations

Annotations by Jardim et al.

Flagella, flagellar attachment zone

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 2
NetGPI no yes: 0, no: 2
Could not find GO cellular_component term for this entry.

Abundance

Amastigote (protein)
Source Evidence on protein Close homologs
Pescher et al. (upgregulation) no yes: 0
Promastigote and amastigote
Source Evidence on protein Close homologs
Lahav et al.
- mRNA
- Protein

Expansion

Sequence features

E9AHT7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHT7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 131 135 PF00656 0.667
CLV_C14_Caspase3-7 376 380 PF00656 0.391
CLV_C14_Caspase3-7 642 646 PF00656 0.647
CLV_C14_Caspase3-7 708 712 PF00656 0.637
CLV_C14_Caspase3-7 79 83 PF00656 0.581
CLV_NRD_NRD_1 125 127 PF00675 0.382
CLV_NRD_NRD_1 275 277 PF00675 0.553
CLV_NRD_NRD_1 398 400 PF00675 0.394
CLV_NRD_NRD_1 617 619 PF00675 0.653
CLV_NRD_NRD_1 659 661 PF00675 0.377
CLV_NRD_NRD_1 789 791 PF00675 0.636
CLV_NRD_NRD_1 818 820 PF00675 0.436
CLV_PCSK_FUR_1 123 127 PF00082 0.613
CLV_PCSK_FUR_1 273 277 PF00082 0.590
CLV_PCSK_KEX2_1 125 127 PF00082 0.615
CLV_PCSK_KEX2_1 273 275 PF00082 0.581
CLV_PCSK_KEX2_1 617 619 PF00082 0.653
CLV_PCSK_KEX2_1 69 71 PF00082 0.665
CLV_PCSK_KEX2_1 755 757 PF00082 0.407
CLV_PCSK_KEX2_1 818 820 PF00082 0.611
CLV_PCSK_KEX2_1 822 824 PF00082 0.554
CLV_PCSK_PC1ET2_1 69 71 PF00082 0.665
CLV_PCSK_PC1ET2_1 755 757 PF00082 0.407
CLV_PCSK_PC1ET2_1 822 824 PF00082 0.624
CLV_PCSK_PC7_1 270 276 PF00082 0.365
CLV_PCSK_PC7_1 818 824 PF00082 0.619
CLV_PCSK_SKI1_1 114 118 PF00082 0.394
CLV_PCSK_SKI1_1 399 403 PF00082 0.393
CLV_PCSK_SKI1_1 487 491 PF00082 0.476
CLV_PCSK_SKI1_1 514 518 PF00082 0.562
CLV_PCSK_SKI1_1 597 601 PF00082 0.526
CLV_PCSK_SKI1_1 660 664 PF00082 0.445
CLV_PCSK_SKI1_1 818 822 PF00082 0.620
DEG_APCC_DBOX_1 20 28 PF00400 0.342
DEG_APCC_DBOX_1 273 281 PF00400 0.361
DEG_APCC_DBOX_1 313 321 PF00400 0.674
DEG_APCC_DBOX_1 845 853 PF00400 0.642
DEG_Nend_UBRbox_2 1 2 PF02207 0.450
DOC_CYCLIN_RxL_1 393 406 PF00134 0.389
DOC_CYCLIN_RxL_1 657 667 PF00134 0.375
DOC_CYCLIN_yClb5_NLxxxL_5 500 507 PF00134 0.406
DOC_CYCLIN_yCln2_LP_2 139 145 PF00134 0.475
DOC_MAPK_gen_1 545 554 PF00069 0.625
DOC_MAPK_MEF2A_6 547 556 PF00069 0.624
DOC_PP2B_LxvP_1 139 142 PF13499 0.482
DOC_USP7_MATH_1 3 7 PF00917 0.371
DOC_USP7_MATH_1 30 34 PF00917 0.560
DOC_USP7_MATH_1 36 40 PF00917 0.544
DOC_USP7_MATH_1 380 384 PF00917 0.403
DOC_USP7_MATH_1 478 482 PF00917 0.397
DOC_USP7_UBL2_3 246 250 PF12436 0.385
DOC_USP7_UBL2_3 508 512 PF12436 0.410
DOC_USP7_UBL2_3 749 753 PF12436 0.381
DOC_USP7_UBL2_3 801 805 PF12436 0.643
DOC_WW_Pin1_4 305 310 PF00397 0.464
LIG_14-3-3_CanoR_1 235 241 PF00244 0.529
LIG_14-3-3_CanoR_1 4 10 PF00244 0.333
LIG_14-3-3_CanoR_1 551 555 PF00244 0.391
LIG_Actin_WH2_2 521 538 PF00022 0.585
LIG_Actin_WH2_2 768 785 PF00022 0.625
LIG_Actin_WH2_2 792 810 PF00022 0.401
LIG_BIR_III_4 134 138 PF00653 0.698
LIG_BRCT_BRCA1_1 182 186 PF00533 0.409
LIG_BRCT_BRCA1_1 5 9 PF00533 0.329
LIG_BRCT_BRCA1_1 768 772 PF00533 0.433
LIG_CSK_EPIYA_1 164 168 PF00017 0.446
LIG_CtBP_PxDLS_1 291 297 PF00389 0.489
LIG_FAT_LD_1 367 375 PF03623 0.627
LIG_FHA_1 136 142 PF00498 0.712
LIG_FHA_1 429 435 PF00498 0.553
LIG_FHA_1 551 557 PF00498 0.389
LIG_FHA_2 168 174 PF00498 0.685
LIG_FHA_2 515 521 PF00498 0.634
LIG_FHA_2 640 646 PF00498 0.644
LIG_FHA_2 91 97 PF00498 0.380
LIG_LIR_Apic_2 56 61 PF02991 0.569
LIG_LIR_Gen_1 172 181 PF02991 0.416
LIG_LIR_Gen_1 361 371 PF02991 0.641
LIG_LIR_Gen_1 456 465 PF02991 0.470
LIG_LIR_Gen_1 574 584 PF02991 0.635
LIG_LIR_Gen_1 769 776 PF02991 0.416
LIG_LIR_Nem_3 172 177 PF02991 0.425
LIG_LIR_Nem_3 361 367 PF02991 0.648
LIG_LIR_Nem_3 381 387 PF02991 0.407
LIG_LIR_Nem_3 456 461 PF02991 0.647
LIG_LIR_Nem_3 57 63 PF02991 0.573
LIG_LIR_Nem_3 574 580 PF02991 0.625
LIG_LIR_Nem_3 769 775 PF02991 0.417
LIG_LYPXL_yS_3 60 63 PF13949 0.564
LIG_NRBOX 366 372 PF00104 0.631
LIG_NRBOX 658 664 PF00104 0.611
LIG_NRBOX 816 822 PF00104 0.619
LIG_PCNA_yPIPBox_3 560 573 PF02747 0.536
LIG_PCNA_yPIPBox_3 809 821 PF02747 0.626
LIG_Rb_LxCxE_1 278 296 PF01857 0.442
LIG_RPA_C_Fungi 121 133 PF08784 0.396
LIG_SH2_CRK 577 581 PF00017 0.631
LIG_SH2_CRK 58 62 PF00017 0.570
LIG_SH2_STAP1 167 171 PF00017 0.689
LIG_SH2_STAP1 533 537 PF00017 0.380
LIG_SH2_STAP1 67 71 PF00017 0.649
LIG_SH3_3 139 145 PF00018 0.475
LIG_SH3_3 300 306 PF00018 0.629
LIG_SH3_3 352 358 PF00018 0.489
LIG_SUMO_SIM_anti_2 426 432 PF11976 0.621
LIG_SUMO_SIM_par_1 308 313 PF11976 0.416
LIG_SUMO_SIM_par_1 552 557 PF11976 0.387
LIG_TRAF2_1 170 173 PF00917 0.685
LIG_TRAF2_1 373 376 PF00917 0.622
LIG_TRAF2_1 416 419 PF00917 0.636
LIG_TRAF2_1 93 96 PF00917 0.619
LIG_TRAF2_2 158 163 PF00917 0.683
LIG_UBA3_1 566 573 PF00899 0.623
MOD_CK1_1 256 262 PF00069 0.360
MOD_CK1_1 308 314 PF00069 0.419
MOD_CK1_1 44 50 PF00069 0.617
MOD_CK1_1 831 837 PF00069 0.695
MOD_CK2_1 167 173 PF00069 0.685
MOD_CK2_1 362 368 PF00069 0.468
MOD_CK2_1 478 484 PF00069 0.395
MOD_CK2_1 514 520 PF00069 0.633
MOD_CK2_1 737 743 PF00069 0.613
MOD_CK2_1 90 96 PF00069 0.382
MOD_GlcNHglycan 254 258 PF01048 0.370
MOD_GlcNHglycan 338 342 PF01048 0.480
MOD_GlcNHglycan 447 450 PF01048 0.469
MOD_GlcNHglycan 717 722 PF01048 0.644
MOD_GlcNHglycan 730 734 PF01048 0.417
MOD_GlcNHglycan 758 761 PF01048 0.425
MOD_GlcNHglycan 763 766 PF01048 0.442
MOD_GlcNHglycan 837 840 PF01048 0.570
MOD_GSK3_1 30 37 PF00069 0.385
MOD_GSK3_1 831 838 PF00069 0.688
MOD_N-GLC_1 220 225 PF02516 0.362
MOD_N-GLC_1 807 812 PF02516 0.637
MOD_NEK2_1 337 342 PF00069 0.410
MOD_NEK2_1 34 39 PF00069 0.364
MOD_NEK2_1 490 495 PF00069 0.662
MOD_NEK2_1 587 592 PF00069 0.481
MOD_NEK2_1 821 826 PF00069 0.629
MOD_NEK2_1 835 840 PF00069 0.424
MOD_NEK2_2 785 790 PF00069 0.398
MOD_PIKK_1 587 593 PF00454 0.509
MOD_PKA_2 234 240 PF00069 0.630
MOD_PKA_2 3 9 PF00069 0.350
MOD_PKA_2 465 471 PF00069 0.385
MOD_PKA_2 550 556 PF00069 0.577
MOD_PKB_1 637 645 PF00069 0.641
MOD_PKB_1 735 743 PF00069 0.617
MOD_Plk_1 253 259 PF00069 0.429
MOD_Plk_1 337 343 PF00069 0.641
MOD_Plk_1 380 386 PF00069 0.489
MOD_Plk_1 644 650 PF00069 0.415
MOD_Plk_1 717 723 PF00069 0.645
MOD_Plk_1 729 735 PF00069 0.434
MOD_Plk_1 766 772 PF00069 0.448
MOD_Plk_2-3 550 556 PF00069 0.391
MOD_Plk_2-3 683 689 PF00069 0.419
MOD_Plk_4 683 689 PF00069 0.419
MOD_Plk_4 767 773 PF00069 0.544
MOD_ProDKin_1 305 311 PF00069 0.461
MOD_SUMO_for_1 402 405 PF00179 0.389
MOD_SUMO_for_1 453 456 PF00179 0.663
MOD_SUMO_rev_2 474 481 PF00179 0.412
MOD_SUMO_rev_2 501 510 PF00179 0.405
MOD_SUMO_rev_2 75 83 PF00179 0.401
MOD_SUMO_rev_2 763 770 PF00179 0.463
MOD_SUMO_rev_2 843 852 PF00179 0.637
TRG_DiLeu_BaEn_1 201 206 PF01217 0.617
TRG_DiLeu_BaEn_1 211 216 PF01217 0.298
TRG_DiLeu_BaEn_3 717 723 PF01217 0.645
TRG_DiLeu_BaEn_4 418 424 PF01217 0.630
TRG_DiLeu_BaLyEn_6 816 821 PF01217 0.614
TRG_ENDOCYTIC_2 577 580 PF00928 0.628
TRG_ENDOCYTIC_2 60 63 PF00928 0.564
TRG_ER_diArg_1 122 125 PF00400 0.395
TRG_ER_diArg_1 272 275 PF00400 0.373
TRG_ER_diArg_1 734 737 PF00400 0.546
TRG_ER_diArg_1 817 819 PF00400 0.625
TRG_NES_CRM1_1 204 218 PF08389 0.615
TRG_NES_CRM1_1 654 667 PF08389 0.377
TRG_Pf-PMV_PEXEL_1 154 159 PF00026 0.628
TRG_Pf-PMV_PEXEL_1 193 197 PF00026 0.514
TRG_Pf-PMV_PEXEL_1 329 334 PF00026 0.638
TRG_Pf-PMV_PEXEL_1 372 376 PF00026 0.622
TRG_Pf-PMV_PEXEL_1 385 389 PF00026 0.376
TRG_Pf-PMV_PEXEL_1 393 397 PF00026 0.482
TRG_Pf-PMV_PEXEL_1 660 665 PF00026 0.376

Homologs

Protein Taxonomy Sequence identity Coverage
A4HAW8 Leishmania braziliensis 74% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS