LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

MYND-type domain-containing protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
MYND-type domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
E9AHS5_LEIIN
TriTrypDb:
LINF_340013200
Length:
469

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 17
NetGPI no yes: 0, no: 17
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AHS5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHS5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 182 184 PF00675 0.427
CLV_NRD_NRD_1 34 36 PF00675 0.450
CLV_NRD_NRD_1 460 462 PF00675 0.543
CLV_PCSK_FUR_1 34 38 PF00082 0.433
CLV_PCSK_KEX2_1 184 186 PF00082 0.430
CLV_PCSK_KEX2_1 34 36 PF00082 0.465
CLV_PCSK_KEX2_1 462 464 PF00082 0.588
CLV_PCSK_PC1ET2_1 184 186 PF00082 0.513
CLV_PCSK_PC1ET2_1 36 38 PF00082 0.469
CLV_PCSK_PC1ET2_1 462 464 PF00082 0.588
CLV_PCSK_SKI1_1 129 133 PF00082 0.381
CLV_PCSK_SKI1_1 252 256 PF00082 0.336
CLV_PCSK_SKI1_1 338 342 PF00082 0.396
CLV_PCSK_SKI1_1 345 349 PF00082 0.393
CLV_PCSK_SKI1_1 36 40 PF00082 0.447
CLV_PCSK_SKI1_1 438 442 PF00082 0.478
DEG_APCC_DBOX_1 337 345 PF00400 0.430
DEG_Nend_UBRbox_3 1 3 PF02207 0.445
DOC_CYCLIN_RxL_1 247 259 PF00134 0.356
DOC_CYCLIN_yCln2_LP_2 318 324 PF00134 0.367
DOC_CYCLIN_yCln2_LP_2 44 50 PF00134 0.406
DOC_MAPK_FxFP_2 74 77 PF00069 0.405
DOC_MAPK_gen_1 183 192 PF00069 0.422
DOC_PP1_RVXF_1 396 402 PF00149 0.398
DOC_PP1_SILK_1 51 56 PF00149 0.490
DOC_PP2B_LxvP_1 282 285 PF13499 0.405
DOC_PP2B_LxvP_1 318 321 PF13499 0.445
DOC_PP4_FxxP_1 223 226 PF00568 0.296
DOC_PP4_FxxP_1 74 77 PF00568 0.405
DOC_PP4_MxPP_1 1 4 PF00568 0.442
DOC_USP7_MATH_1 456 460 PF00917 0.504
DOC_USP7_UBL2_3 15 19 PF12436 0.546
DOC_USP7_UBL2_3 398 402 PF12436 0.367
DOC_WW_Pin1_4 167 172 PF00397 0.513
DOC_WW_Pin1_4 202 207 PF00397 0.444
DOC_WW_Pin1_4 236 241 PF00397 0.436
DOC_WW_Pin1_4 79 84 PF00397 0.469
DOC_WW_Pin1_4 97 102 PF00397 0.414
LIG_14-3-3_CanoR_1 209 216 PF00244 0.406
LIG_14-3-3_CanoR_1 35 41 PF00244 0.436
LIG_14-3-3_CanoR_1 362 368 PF00244 0.524
LIG_14-3-3_CanoR_1 436 441 PF00244 0.530
LIG_14-3-3_CanoR_1 90 95 PF00244 0.513
LIG_Actin_WH2_2 114 131 PF00022 0.372
LIG_APCC_ABBA_1 25 30 PF00400 0.408
LIG_BRCT_BRCA1_1 109 113 PF00533 0.381
LIG_deltaCOP1_diTrp_1 29 40 PF00928 0.417
LIG_EH_1 218 222 PF12763 0.364
LIG_eIF4E_1 250 256 PF01652 0.324
LIG_FHA_1 100 106 PF00498 0.470
LIG_FHA_1 442 448 PF00498 0.567
LIG_FHA_2 157 163 PF00498 0.600
LIG_FHA_2 257 263 PF00498 0.382
LIG_LIR_Apic_2 72 77 PF02991 0.401
LIG_LIR_Gen_1 133 143 PF02991 0.335
LIG_LIR_Gen_1 380 390 PF02991 0.351
LIG_LIR_Gen_1 64 75 PF02991 0.387
LIG_LIR_Nem_3 110 116 PF02991 0.366
LIG_LIR_Nem_3 133 138 PF02991 0.345
LIG_LIR_Nem_3 199 204 PF02991 0.392
LIG_LIR_Nem_3 380 386 PF02991 0.336
LIG_LIR_Nem_3 394 400 PF02991 0.378
LIG_LIR_Nem_3 64 70 PF02991 0.383
LIG_LYPXL_SIV_4 378 386 PF13949 0.424
LIG_PCNA_PIPBox_1 106 115 PF02747 0.488
LIG_PCNA_yPIPBox_3 421 429 PF02747 0.534
LIG_Pex14_2 221 225 PF04695 0.334
LIG_Pex14_2 397 401 PF04695 0.499
LIG_SH2_CRK 379 383 PF00017 0.337
LIG_SH2_CRK 67 71 PF00017 0.365
LIG_SH2_NCK_1 150 154 PF00017 0.445
LIG_SH2_NCK_1 379 383 PF00017 0.315
LIG_SH2_NCK_1 67 71 PF00017 0.364
LIG_SH2_SRC 150 153 PF00017 0.441
LIG_SH2_STAP1 23 27 PF00017 0.422
LIG_SH2_STAP1 250 254 PF00017 0.321
LIG_SH2_STAP1 379 383 PF00017 0.337
LIG_SH2_STAT5 146 149 PF00017 0.431
LIG_SH2_STAT5 235 238 PF00017 0.523
LIG_SH2_STAT5 379 382 PF00017 0.338
LIG_SH2_STAT5 383 386 PF00017 0.338
LIG_SH2_STAT5 67 70 PF00017 0.347
LIG_SH3_3 384 390 PF00018 0.474
LIG_SH3_3 82 88 PF00018 0.441
LIG_TYR_ITIM 377 382 PF00017 0.338
LIG_TYR_ITSM 63 70 PF00017 0.356
LIG_UBA3_1 340 345 PF00899 0.410
LIG_WRC_WIRS_1 325 330 PF05994 0.453
MOD_CDK_SPxK_1 236 242 PF00069 0.428
MOD_CDK_SPxxK_3 202 209 PF00069 0.442
MOD_CDK_SPxxK_3 97 104 PF00069 0.402
MOD_CK2_1 97 103 PF00069 0.428
MOD_GSK3_1 117 124 PF00069 0.463
MOD_GSK3_1 13 20 PF00069 0.500
MOD_GSK3_1 165 172 PF00069 0.539
MOD_GSK3_1 441 448 PF00069 0.622
MOD_NEK2_1 117 122 PF00069 0.460
MOD_NEK2_1 165 170 PF00069 0.526
MOD_NEK2_1 256 261 PF00069 0.380
MOD_NEK2_1 312 317 PF00069 0.381
MOD_NEK2_1 377 382 PF00069 0.346
MOD_NEK2_1 441 446 PF00069 0.488
MOD_NEK2_1 48 53 PF00069 0.544
MOD_NEK2_2 245 250 PF00069 0.356
MOD_PIKK_1 156 162 PF00454 0.562
MOD_PIKK_1 348 354 PF00454 0.507
MOD_PK_1 49 55 PF00069 0.420
MOD_PKA_1 36 42 PF00069 0.454
MOD_PKA_2 208 214 PF00069 0.410
MOD_PKA_2 267 273 PF00069 0.622
MOD_PKA_2 36 42 PF00069 0.423
MOD_PKA_2 361 367 PF00069 0.540
MOD_PKA_2 48 54 PF00069 0.407
MOD_Plk_1 17 23 PF00069 0.549
MOD_Plk_1 196 202 PF00069 0.443
MOD_Plk_1 29 35 PF00069 0.439
MOD_Plk_1 330 336 PF00069 0.488
MOD_Plk_1 65 71 PF00069 0.363
MOD_Plk_2-3 186 192 PF00069 0.452
MOD_Plk_4 196 202 PF00069 0.486
MOD_Plk_4 250 256 PF00069 0.343
MOD_Plk_4 377 383 PF00069 0.338
MOD_Plk_4 436 442 PF00069 0.525
MOD_Plk_4 49 55 PF00069 0.405
MOD_Plk_4 65 71 PF00069 0.358
MOD_Plk_4 90 96 PF00069 0.511
MOD_ProDKin_1 167 173 PF00069 0.505
MOD_ProDKin_1 202 208 PF00069 0.438
MOD_ProDKin_1 236 242 PF00069 0.431
MOD_ProDKin_1 79 85 PF00069 0.469
MOD_ProDKin_1 97 103 PF00069 0.416
MOD_SUMO_for_1 334 337 PF00179 0.439
MOD_SUMO_rev_2 158 166 PF00179 0.644
MOD_SUMO_rev_2 18 27 PF00179 0.428
MOD_SUMO_rev_2 337 347 PF00179 0.415
MOD_SUMO_rev_2 459 464 PF00179 0.538
MOD_SUMO_rev_2 8 17 PF00179 0.459
TRG_DiLeu_BaEn_1 420 425 PF01217 0.449
TRG_DiLeu_BaEn_2 196 202 PF01217 0.375
TRG_DiLeu_BaEn_2 341 347 PF01217 0.414
TRG_DiLeu_BaEn_4 342 348 PF01217 0.419
TRG_DiLeu_BaLyEn_6 112 117 PF01217 0.349
TRG_ENDOCYTIC_2 150 153 PF00928 0.461
TRG_ENDOCYTIC_2 28 31 PF00928 0.412
TRG_ENDOCYTIC_2 379 382 PF00928 0.337
TRG_ENDOCYTIC_2 383 386 PF00928 0.337
TRG_ENDOCYTIC_2 389 392 PF00928 0.374
TRG_ENDOCYTIC_2 67 70 PF00928 0.366
TRG_ER_diArg_1 182 185 PF00400 0.417
TRG_ER_diArg_1 33 35 PF00400 0.437
TRG_ER_diArg_1 461 464 PF00400 0.482
TRG_ER_diArg_1 54 57 PF00400 0.411
TRG_NLS_MonoExtN_4 34 39 PF00514 0.490
TRG_Pf-PMV_PEXEL_1 302 306 PF00026 0.465
TRG_Pf-PMV_PEXEL_1 338 342 PF00026 0.408

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PA50 Leptomonas seymouri 89% 94%
A0A0N1PBN6 Leptomonas seymouri 26% 67%
A0A0S4JJ07 Bodo saltans 70% 100%
A0A1X0NY35 Trypanosomatidae 25% 67%
A0A1X0P990 Trypanosomatidae 73% 96%
A0A3Q8IE69 Leishmania donovani 100% 100%
A0A3R7MZ34 Trypanosoma rangeli 28% 69%
A0A3R7N7Y7 Trypanosoma rangeli 71% 97%
A4HAI4 Leishmania braziliensis 93% 100%
C9ZN08 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 69% 98%
C9ZVC0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 26% 68%
E9AWF4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 69%
E9B4P5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 96% 100%
Q4Q3D1 Leishmania major 97% 100%
Q4QB18 Leishmania major 27% 68%
V5BJD7 Trypanosoma cruzi 72% 97%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS