LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Annotations Function or PPIs Localization Phosphorylation Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
E9AHR4_LEIIN
TriTrypDb:
LINF_330033800
Length:
1051

Annotations

Annotations by Jardim et al.

Flagella, Flagellum attachment zone 12

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Phosphorylation

Amastigote: 119

Expansion

Sequence features

E9AHR4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHR4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1013 1017 PF00656 0.628
CLV_C14_Caspase3-7 184 188 PF00656 0.421
CLV_C14_Caspase3-7 200 204 PF00656 0.384
CLV_C14_Caspase3-7 465 469 PF00656 0.585
CLV_C14_Caspase3-7 489 493 PF00656 0.653
CLV_C14_Caspase3-7 660 664 PF00656 0.485
CLV_C14_Caspase3-7 683 687 PF00656 0.502
CLV_C14_Caspase3-7 988 992 PF00656 0.563
CLV_NRD_NRD_1 21 23 PF00675 0.394
CLV_NRD_NRD_1 215 217 PF00675 0.522
CLV_NRD_NRD_1 42 44 PF00675 0.616
CLV_NRD_NRD_1 52 54 PF00675 0.516
CLV_NRD_NRD_1 557 559 PF00675 0.473
CLV_NRD_NRD_1 589 591 PF00675 0.420
CLV_NRD_NRD_1 613 615 PF00675 0.441
CLV_NRD_NRD_1 764 766 PF00675 0.498
CLV_NRD_NRD_1 791 793 PF00675 0.373
CLV_PCSK_KEX2_1 112 114 PF00082 0.524
CLV_PCSK_KEX2_1 21 23 PF00082 0.394
CLV_PCSK_KEX2_1 214 216 PF00082 0.522
CLV_PCSK_KEX2_1 420 422 PF00082 0.562
CLV_PCSK_KEX2_1 52 54 PF00082 0.572
CLV_PCSK_KEX2_1 589 591 PF00082 0.420
CLV_PCSK_KEX2_1 764 766 PF00082 0.498
CLV_PCSK_KEX2_1 791 793 PF00082 0.373
CLV_PCSK_KEX2_1 857 859 PF00082 0.378
CLV_PCSK_PC1ET2_1 112 114 PF00082 0.504
CLV_PCSK_PC1ET2_1 420 422 PF00082 0.562
CLV_PCSK_PC1ET2_1 857 859 PF00082 0.378
CLV_PCSK_SKI1_1 151 155 PF00082 0.384
CLV_PCSK_SKI1_1 289 293 PF00082 0.660
CLV_PCSK_SKI1_1 37 41 PF00082 0.573
CLV_PCSK_SKI1_1 599 603 PF00082 0.466
CLV_PCSK_SKI1_1 615 619 PF00082 0.504
CLV_PCSK_SKI1_1 667 671 PF00082 0.398
CLV_PCSK_SKI1_1 791 795 PF00082 0.395
CLV_PCSK_SKI1_1 803 807 PF00082 0.476
CLV_PCSK_SKI1_1 870 874 PF00082 0.441
DEG_APCC_DBOX_1 213 221 PF00400 0.519
DEG_APCC_DBOX_1 42 50 PF00400 0.612
DEG_APCC_DBOX_1 790 798 PF00400 0.369
DOC_CKS1_1 240 245 PF01111 0.419
DOC_CYCLIN_RxL_1 283 297 PF00134 0.539
DOC_CYCLIN_yCln2_LP_2 703 709 PF00134 0.486
DOC_MAPK_DCC_7 225 233 PF00069 0.565
DOC_MAPK_DCC_7 43 51 PF00069 0.523
DOC_MAPK_DCC_7 840 848 PF00069 0.488
DOC_MAPK_gen_1 366 374 PF00069 0.396
DOC_MAPK_gen_1 791 797 PF00069 0.394
DOC_MAPK_gen_1 857 863 PF00069 0.401
DOC_MAPK_MEF2A_6 225 233 PF00069 0.565
DOC_MAPK_MEF2A_6 53 62 PF00069 0.410
DOC_MAPK_MEF2A_6 840 848 PF00069 0.511
DOC_PP1_RVXF_1 287 294 PF00149 0.581
DOC_PP2B_LxvP_1 309 312 PF13499 0.610
DOC_PP2B_PxIxI_1 228 234 PF00149 0.557
DOC_PP2B_PxIxI_1 314 320 PF00149 0.598
DOC_PP4_FxxP_1 445 448 PF00568 0.576
DOC_PP4_FxxP_1 972 975 PF00568 0.434
DOC_PP4_MxPP_1 848 851 PF00568 0.420
DOC_USP7_MATH_1 1041 1045 PF00917 0.677
DOC_USP7_MATH_1 197 201 PF00917 0.304
DOC_USP7_MATH_1 235 239 PF00917 0.443
DOC_USP7_MATH_1 279 283 PF00917 0.561
DOC_USP7_MATH_1 448 452 PF00917 0.587
DOC_USP7_MATH_1 507 511 PF00917 0.711
DOC_USP7_MATH_1 640 644 PF00917 0.518
DOC_USP7_MATH_1 692 696 PF00917 0.453
DOC_USP7_MATH_1 739 743 PF00917 0.480
DOC_USP7_MATH_1 760 764 PF00917 0.593
DOC_USP7_MATH_1 771 775 PF00917 0.381
DOC_USP7_MATH_1 776 780 PF00917 0.389
DOC_USP7_MATH_1 935 939 PF00917 0.634
DOC_USP7_UBL2_3 40 44 PF12436 0.556
DOC_WW_Pin1_4 1037 1042 PF00397 0.661
DOC_WW_Pin1_4 116 121 PF00397 0.495
DOC_WW_Pin1_4 239 244 PF00397 0.425
DOC_WW_Pin1_4 523 528 PF00397 0.673
DOC_WW_Pin1_4 62 67 PF00397 0.434
DOC_WW_Pin1_4 641 646 PF00397 0.493
DOC_WW_Pin1_4 754 759 PF00397 0.486
DOC_WW_Pin1_4 927 932 PF00397 0.570
DOC_WW_Pin1_4 939 944 PF00397 0.489
DOC_WW_Pin1_4 971 976 PF00397 0.424
LIG_14-3-3_CanoR_1 1028 1036 PF00244 0.656
LIG_14-3-3_CanoR_1 151 161 PF00244 0.422
LIG_14-3-3_CanoR_1 21 25 PF00244 0.420
LIG_14-3-3_CanoR_1 215 221 PF00244 0.534
LIG_14-3-3_CanoR_1 52 56 PF00244 0.529
LIG_14-3-3_CanoR_1 573 582 PF00244 0.391
LIG_14-3-3_CanoR_1 812 820 PF00244 0.376
LIG_14-3-3_CanoR_1 964 973 PF00244 0.479
LIG_14-3-3_CanoR_1 983 988 PF00244 0.588
LIG_Actin_WH2_2 7 23 PF00022 0.450
LIG_APCC_ABBA_1 430 435 PF00400 0.522
LIG_BIR_II_1 1 5 PF00653 0.540
LIG_BIR_III_2 775 779 PF00653 0.536
LIG_BIR_III_4 468 472 PF00653 0.594
LIG_BRCT_BRCA1_1 220 224 PF00533 0.534
LIG_BRCT_BRCA1_1 985 989 PF00533 0.495
LIG_Clathr_ClatBox_1 797 801 PF01394 0.445
LIG_CtBP_PxDLS_1 48 52 PF00389 0.478
LIG_CtBP_PxDLS_1 645 649 PF00389 0.413
LIG_deltaCOP1_diTrp_1 138 148 PF00928 0.370
LIG_DLG_GKlike_1 680 688 PF00625 0.398
LIG_EH1_1 581 589 PF00400 0.318
LIG_FHA_1 1028 1034 PF00498 0.581
LIG_FHA_1 264 270 PF00498 0.440
LIG_FHA_1 314 320 PF00498 0.588
LIG_FHA_1 427 433 PF00498 0.506
LIG_FHA_1 5 11 PF00498 0.483
LIG_FHA_1 57 63 PF00498 0.422
LIG_FHA_1 671 677 PF00498 0.586
LIG_FHA_1 712 718 PF00498 0.647
LIG_FHA_1 832 838 PF00498 0.443
LIG_FHA_1 871 877 PF00498 0.552
LIG_FHA_1 920 926 PF00498 0.568
LIG_FHA_2 1011 1017 PF00498 0.719
LIG_FHA_2 180 186 PF00498 0.406
LIG_FHA_2 240 246 PF00498 0.613
LIG_FHA_2 536 542 PF00498 0.524
LIG_FHA_2 601 607 PF00498 0.451
LIG_FHA_2 69 75 PF00498 0.438
LIG_FHA_2 904 910 PF00498 0.432
LIG_FHA_2 914 920 PF00498 0.392
LIG_LIR_Apic_2 237 243 PF02991 0.399
LIG_LIR_Apic_2 443 448 PF02991 0.553
LIG_LIR_Apic_2 79 83 PF02991 0.508
LIG_LIR_Gen_1 400 408 PF02991 0.410
LIG_LIR_Gen_1 663 672 PF02991 0.436
LIG_LIR_Nem_3 105 110 PF02991 0.409
LIG_LIR_Nem_3 400 405 PF02991 0.408
LIG_LIR_Nem_3 425 430 PF02991 0.506
LIG_LIR_Nem_3 431 436 PF02991 0.539
LIG_LIR_Nem_3 663 668 PF02991 0.436
LIG_LIR_Nem_3 874 880 PF02991 0.519
LIG_MAD2 667 675 PF02301 0.486
LIG_NRP_CendR_1 1050 1051 PF00754 0.664
LIG_PCNA_yPIPBox_3 337 350 PF02747 0.486
LIG_PTAP_UEV_1 500 505 PF05743 0.544
LIG_PTB_Apo_2 541 548 PF02174 0.445
LIG_PTB_Phospho_1 541 547 PF10480 0.444
LIG_SH2_CRK 375 379 PF00017 0.368
LIG_SH2_CRK 547 551 PF00017 0.435
LIG_SH2_CRK 582 586 PF00017 0.405
LIG_SH2_CRK 665 669 PF00017 0.427
LIG_SH2_CRK 751 755 PF00017 0.423
LIG_SH2_NCK_1 136 140 PF00017 0.443
LIG_SH2_PTP2 80 83 PF00017 0.500
LIG_SH2_SRC 136 139 PF00017 0.445
LIG_SH2_SRC 729 732 PF00017 0.351
LIG_SH2_SRC 80 83 PF00017 0.500
LIG_SH2_SRC 880 883 PF00017 0.432
LIG_SH2_STAP1 136 140 PF00017 0.371
LIG_SH2_STAP1 399 403 PF00017 0.405
LIG_SH2_STAP1 547 551 PF00017 0.435
LIG_SH2_STAP1 665 669 PF00017 0.381
LIG_SH2_STAP1 877 881 PF00017 0.511
LIG_SH2_STAT3 247 250 PF00017 0.481
LIG_SH2_STAT5 170 173 PF00017 0.479
LIG_SH2_STAT5 240 243 PF00017 0.410
LIG_SH2_STAT5 28 31 PF00017 0.554
LIG_SH2_STAT5 302 305 PF00017 0.586
LIG_SH2_STAT5 729 732 PF00017 0.351
LIG_SH2_STAT5 80 83 PF00017 0.500
LIG_SH2_STAT5 826 829 PF00017 0.449
LIG_SH3_1 80 86 PF00018 0.509
LIG_SH3_3 309 315 PF00018 0.611
LIG_SH3_3 39 45 PF00018 0.652
LIG_SH3_3 498 504 PF00018 0.617
LIG_SH3_3 52 58 PF00018 0.411
LIG_SH3_3 521 527 PF00018 0.703
LIG_SH3_3 63 69 PF00018 0.453
LIG_SH3_3 653 659 PF00018 0.422
LIG_SH3_3 669 675 PF00018 0.417
LIG_SH3_3 78 84 PF00018 0.519
LIG_Sin3_3 546 553 PF02671 0.374
LIG_SUMO_SIM_anti_2 59 65 PF11976 0.406
LIG_SUMO_SIM_anti_2 814 820 PF11976 0.322
LIG_SUMO_SIM_par_1 265 271 PF11976 0.456
LIG_TRAF2_1 182 185 PF00917 0.451
LIG_TRAF2_1 242 245 PF00917 0.415
LIG_TRAF2_1 335 338 PF00917 0.403
LIG_TRAF2_1 534 537 PF00917 0.550
LIG_TRAF2_1 603 606 PF00917 0.408
LIG_TRAF2_2 45 50 PF00917 0.520
LIG_UBA3_1 339 345 PF00899 0.437
LIG_UBA3_1 414 420 PF00899 0.519
LIG_UBA3_1 797 803 PF00899 0.419
LIG_WW_1 77 80 PF00397 0.520
MOD_CDK_SPK_2 927 932 PF00069 0.570
MOD_CDK_SPxxK_3 239 246 PF00069 0.410
MOD_CDK_SPxxK_3 971 978 PF00069 0.421
MOD_CK1_1 1004 1010 PF00069 0.718
MOD_CK1_1 310 316 PF00069 0.594
MOD_CK1_1 380 386 PF00069 0.391
MOD_CK1_1 419 425 PF00069 0.542
MOD_CK1_1 475 481 PF00069 0.610
MOD_CK1_1 493 499 PF00069 0.633
MOD_CK1_1 526 532 PF00069 0.632
MOD_CK1_1 644 650 PF00069 0.585
MOD_CK1_1 695 701 PF00069 0.497
MOD_CK1_1 814 820 PF00069 0.471
MOD_CK1_1 927 933 PF00069 0.478
MOD_CK2_1 179 185 PF00069 0.440
MOD_CK2_1 239 245 PF00069 0.444
MOD_CK2_1 279 285 PF00069 0.607
MOD_CK2_1 357 363 PF00069 0.600
MOD_CK2_1 535 541 PF00069 0.517
MOD_CK2_1 600 606 PF00069 0.494
MOD_CK2_1 68 74 PF00069 0.421
MOD_CK2_1 913 919 PF00069 0.390
MOD_CK2_1 982 988 PF00069 0.523
MOD_Cter_Amidation 612 615 PF01082 0.444
MOD_GlcNHglycan 1043 1046 PF01048 0.662
MOD_GlcNHglycan 121 124 PF01048 0.481
MOD_GlcNHglycan 273 276 PF01048 0.562
MOD_GlcNHglycan 285 288 PF01048 0.538
MOD_GlcNHglycan 358 362 PF01048 0.619
MOD_GlcNHglycan 421 424 PF01048 0.617
MOD_GlcNHglycan 488 491 PF01048 0.714
MOD_GlcNHglycan 492 495 PF01048 0.705
MOD_GlcNHglycan 501 504 PF01048 0.529
MOD_GlcNHglycan 532 535 PF01048 0.603
MOD_GlcNHglycan 695 698 PF01048 0.579
MOD_GlcNHglycan 707 710 PF01048 0.494
MOD_GlcNHglycan 722 725 PF01048 0.524
MOD_GlcNHglycan 741 744 PF01048 0.300
MOD_GlcNHglycan 926 929 PF01048 0.579
MOD_GSK3_1 1006 1013 PF00069 0.763
MOD_GSK3_1 1023 1030 PF00069 0.624
MOD_GSK3_1 1035 1042 PF00069 0.667
MOD_GSK3_1 112 119 PF00069 0.483
MOD_GSK3_1 152 159 PF00069 0.376
MOD_GSK3_1 175 182 PF00069 0.475
MOD_GSK3_1 197 204 PF00069 0.442
MOD_GSK3_1 227 234 PF00069 0.590
MOD_GSK3_1 235 242 PF00069 0.619
MOD_GSK3_1 279 286 PF00069 0.558
MOD_GSK3_1 303 310 PF00069 0.715
MOD_GSK3_1 319 326 PF00069 0.478
MOD_GSK3_1 422 429 PF00069 0.531
MOD_GSK3_1 482 489 PF00069 0.611
MOD_GSK3_1 526 533 PF00069 0.641
MOD_GSK3_1 58 65 PF00069 0.413
MOD_GSK3_1 616 623 PF00069 0.461
MOD_GSK3_1 640 647 PF00069 0.559
MOD_GSK3_1 735 742 PF00069 0.600
MOD_GSK3_1 899 906 PF00069 0.576
MOD_GSK3_1 935 942 PF00069 0.570
MOD_GSK3_1 948 955 PF00069 0.588
MOD_GSK3_1 997 1004 PF00069 0.682
MOD_N-GLC_1 1001 1006 PF02516 0.601
MOD_N-GLC_1 253 258 PF02516 0.417
MOD_N-GLC_1 263 268 PF02516 0.412
MOD_N-GLC_1 389 394 PF02516 0.353
MOD_N-GLC_1 832 837 PF02516 0.508
MOD_N-GLC_1 884 889 PF02516 0.357
MOD_N-GLC_1 935 940 PF02516 0.527
MOD_N-GLC_1 964 969 PF02516 0.480
MOD_NEK2_1 121 126 PF00069 0.587
MOD_NEK2_1 154 159 PF00069 0.403
MOD_NEK2_1 20 25 PF00069 0.418
MOD_NEK2_1 263 268 PF00069 0.412
MOD_NEK2_1 292 297 PF00069 0.615
MOD_NEK2_1 357 362 PF00069 0.625
MOD_NEK2_1 621 626 PF00069 0.437
MOD_NEK2_1 910 915 PF00069 0.576
MOD_NEK2_2 235 240 PF00069 0.504
MOD_NEK2_2 428 433 PF00069 0.508
MOD_PIKK_1 1004 1010 PF00454 0.724
MOD_PIKK_1 121 127 PF00454 0.493
MOD_PIKK_1 128 134 PF00454 0.402
MOD_PIKK_1 292 298 PF00454 0.614
MOD_PIKK_1 4 10 PF00454 0.489
MOD_PK_1 216 222 PF00069 0.480
MOD_PK_1 952 958 PF00069 0.581
MOD_PKA_1 112 118 PF00069 0.475
MOD_PKA_2 1027 1033 PF00069 0.574
MOD_PKA_2 112 118 PF00069 0.549
MOD_PKA_2 20 26 PF00069 0.426
MOD_PKA_2 51 57 PF00069 0.569
MOD_PKA_2 557 563 PF00069 0.516
MOD_PKA_2 811 817 PF00069 0.379
MOD_PKA_2 963 969 PF00069 0.550
MOD_PKA_2 982 988 PF00069 0.532
MOD_PKB_1 214 222 PF00069 0.480
MOD_Plk_1 141 147 PF00069 0.361
MOD_Plk_1 263 269 PF00069 0.415
MOD_Plk_1 380 386 PF00069 0.391
MOD_Plk_1 389 395 PF00069 0.403
MOD_Plk_1 571 577 PF00069 0.413
MOD_Plk_1 814 820 PF00069 0.524
MOD_Plk_1 832 838 PF00069 0.410
MOD_Plk_1 884 890 PF00069 0.355
MOD_Plk_1 964 970 PF00069 0.498
MOD_Plk_2-3 919 925 PF00069 0.388
MOD_Plk_4 1007 1013 PF00069 0.699
MOD_Plk_4 197 203 PF00069 0.410
MOD_Plk_4 263 269 PF00069 0.423
MOD_Plk_4 380 386 PF00069 0.427
MOD_Plk_4 398 404 PF00069 0.391
MOD_Plk_4 428 434 PF00069 0.552
MOD_Plk_4 448 454 PF00069 0.576
MOD_Plk_4 58 64 PF00069 0.568
MOD_Plk_4 644 650 PF00069 0.487
MOD_Plk_4 680 686 PF00069 0.444
MOD_Plk_4 76 82 PF00069 0.464
MOD_Plk_4 814 820 PF00069 0.492
MOD_Plk_4 833 839 PF00069 0.433
MOD_Plk_4 913 919 PF00069 0.462
MOD_ProDKin_1 1037 1043 PF00069 0.662
MOD_ProDKin_1 116 122 PF00069 0.486
MOD_ProDKin_1 239 245 PF00069 0.423
MOD_ProDKin_1 523 529 PF00069 0.672
MOD_ProDKin_1 62 68 PF00069 0.431
MOD_ProDKin_1 641 647 PF00069 0.493
MOD_ProDKin_1 754 760 PF00069 0.485
MOD_ProDKin_1 927 933 PF00069 0.570
MOD_ProDKin_1 939 945 PF00069 0.493
MOD_ProDKin_1 971 977 PF00069 0.419
MOD_SUMO_rev_2 238 248 PF00179 0.416
MOD_SUMO_rev_2 26 34 PF00179 0.616
MOD_SUMO_rev_2 799 805 PF00179 0.424
MOD_SUMO_rev_2 919 927 PF00179 0.457
TRG_DiLeu_BaEn_1 257 262 PF01217 0.416
TRG_DiLeu_BaEn_1 801 806 PF01217 0.400
TRG_DiLeu_BaLyEn_6 972 977 PF01217 0.407
TRG_ENDOCYTIC_2 136 139 PF00928 0.374
TRG_ENDOCYTIC_2 150 153 PF00928 0.431
TRG_ENDOCYTIC_2 249 252 PF00928 0.406
TRG_ENDOCYTIC_2 375 378 PF00928 0.361
TRG_ENDOCYTIC_2 547 550 PF00928 0.357
TRG_ENDOCYTIC_2 582 585 PF00928 0.403
TRG_ENDOCYTIC_2 665 668 PF00928 0.432
TRG_ENDOCYTIC_2 826 829 PF00928 0.449
TRG_ER_diArg_1 20 22 PF00400 0.384
TRG_ER_diArg_1 214 216 PF00400 0.473
TRG_ER_diArg_1 456 459 PF00400 0.619
TRG_ER_diArg_1 51 53 PF00400 0.494
TRG_ER_diArg_1 588 590 PF00400 0.398
TRG_ER_diArg_1 764 766 PF00400 0.515
TRG_ER_diArg_1 791 793 PF00400 0.359
TRG_NES_CRM1_1 257 271 PF08389 0.444
TRG_NES_CRM1_1 381 394 PF08389 0.400
TRG_Pf-PMV_PEXEL_1 22 26 PF00026 0.406
TRG_Pf-PMV_PEXEL_1 978 982 PF00026 0.382
TRG_Pf-PMV_PEXEL_1 99 104 PF00026 0.409

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I9F7 Leptomonas seymouri 56% 100%
A0A3S5H7V1 Leishmania donovani 100% 100%
A4HLV7 Leishmania braziliensis 71% 99%
E9B485 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
Q4Q3U1 Leishmania major 93% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS