Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AHP9_LEIIN

TriTrypDb:

LINF_330032100

Length:

525

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AHP9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHP9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	210	214	PF00656	0.489
CLV_C14_Caspase3-7	255	259	PF00656	0.646
CLV_C14_Caspase3-7	479	483	PF00656	0.559
CLV_C14_Caspase3-7	58	62	PF00656	0.585
CLV_NRD_NRD_1	176	178	PF00675	0.501
CLV_NRD_NRD_1	193	195	PF00675	0.482
CLV_NRD_NRD_1	458	460	PF00675	0.420
CLV_PCSK_FUR_1	190	194	PF00082	0.543
CLV_PCSK_KEX2_1	176	178	PF00082	0.501
CLV_PCSK_KEX2_1	192	194	PF00082	0.490
CLV_PCSK_KEX2_1	458	460	PF00082	0.420
CLV_PCSK_SKI1_1	193	197	PF00082	0.478
CLV_PCSK_SKI1_1	327	331	PF00082	0.663
CLV_PCSK_SKI1_1	365	369	PF00082	0.489
CLV_PCSK_SKI1_1	395	399	PF00082	0.407
CLV_PCSK_SKI1_1	8	12	PF00082	0.581
DEG_APCC_DBOX_1	364	372	PF00400	0.487
DEG_SCF_FBW7_1	299	306	PF00400	0.561
DEG_SCF_FBW7_1	310	315	PF00400	0.625
DEG_SPOP_SBC_1	304	308	PF00917	0.633
DEG_SPOP_SBC_1	312	316	PF00917	0.590
DOC_ANK_TNKS_1	469	476	PF00023	0.458
DOC_CKS1_1	442	447	PF01111	0.371
DOC_CYCLIN_RxL_1	190	197	PF00134	0.539
DOC_CYCLIN_RxL_1	392	401	PF00134	0.397
DOC_CYCLIN_yCln2_LP_2	519	525	PF00134	0.507
DOC_USP7_MATH_1	113	117	PF00917	0.476
DOC_USP7_MATH_1	156	160	PF00917	0.784
DOC_USP7_MATH_1	250	254	PF00917	0.578
DOC_USP7_MATH_1	304	308	PF00917	0.639
DOC_USP7_MATH_1	312	316	PF00917	0.603
DOC_USP7_MATH_1	344	348	PF00917	0.687
DOC_USP7_MATH_1	350	354	PF00917	0.597
DOC_USP7_MATH_1	413	417	PF00917	0.643
DOC_WW_Pin1_4	148	153	PF00397	0.564
DOC_WW_Pin1_4	299	304	PF00397	0.599
DOC_WW_Pin1_4	308	313	PF00397	0.696
DOC_WW_Pin1_4	340	345	PF00397	0.666
DOC_WW_Pin1_4	346	351	PF00397	0.741
DOC_WW_Pin1_4	370	375	PF00397	0.493
DOC_WW_Pin1_4	441	446	PF00397	0.374
LIG_14-3-3_CanoR_1	130	135	PF00244	0.440
LIG_14-3-3_CanoR_1	198	204	PF00244	0.488
LIG_14-3-3_CanoR_1	23	31	PF00244	0.702
LIG_14-3-3_CanoR_1	325	332	PF00244	0.714
LIG_14-3-3_CanoR_1	379	385	PF00244	0.431
LIG_14-3-3_CanoR_1	395	400	PF00244	0.415
LIG_14-3-3_CanoR_1	88	92	PF00244	0.659
LIG_AP2alpha_2	83	85	PF02296	0.566
LIG_BRCT_BRCA1_1	69	73	PF00533	0.676
LIG_BRCT_BRCA1_2	69	75	PF00533	0.616
LIG_deltaCOP1_diTrp_1	127	131	PF00928	0.473
LIG_deltaCOP1_diTrp_1	411	418	PF00928	0.574
LIG_EVH1_2	288	292	PF00568	0.611
LIG_EVH1_2	445	449	PF00568	0.377
LIG_FHA_1	112	118	PF00498	0.427
LIG_FHA_1	2	8	PF00498	0.560
LIG_FHA_1	294	300	PF00498	0.663
LIG_FHA_1	381	387	PF00498	0.585
LIG_FHA_1	388	394	PF00498	0.304
LIG_FHA_1	514	520	PF00498	0.395
LIG_FHA_2	178	184	PF00498	0.583
LIG_FHA_2	317	323	PF00498	0.761
LIG_FHA_2	396	402	PF00498	0.411
LIG_FHA_2	418	424	PF00498	0.530
LIG_FHA_2	477	483	PF00498	0.575
LIG_FHA_2	88	94	PF00498	0.599
LIG_Integrin_RGD_1	234	236	PF01839	0.641
LIG_LIR_Apic_2	89	94	PF02991	0.590
LIG_LIR_Gen_1	127	134	PF02991	0.456
LIG_LIR_Gen_1	201	211	PF02991	0.540
LIG_LIR_Gen_1	248	257	PF02991	0.543
LIG_LIR_Gen_1	38	44	PF02991	0.560
LIG_LIR_Gen_1	415	425	PF02991	0.466
LIG_LIR_Nem_3	127	131	PF02991	0.473
LIG_LIR_Nem_3	197	203	PF02991	0.541
LIG_LIR_Nem_3	248	254	PF02991	0.563
LIG_LIR_Nem_3	38	43	PF02991	0.686
LIG_Pex14_2	124	128	PF04695	0.485
LIG_SH2_NCK_1	242	246	PF00017	0.511
LIG_SH2_STAP1	203	207	PF00017	0.488
LIG_SH2_STAP1	40	44	PF00017	0.543
LIG_SH2_STAT5	362	365	PF00017	0.353
LIG_SH3_3	26	32	PF00018	0.617
LIG_SH3_3	282	288	PF00018	0.668
LIG_SH3_3	439	445	PF00018	0.404
LIG_SH3_3	78	84	PF00018	0.607
LIG_TRAF2_1	180	183	PF00917	0.507
LIG_WW_3	444	448	PF00397	0.395
MOD_CDK_SPxK_1	441	447	PF00069	0.374
MOD_CK1_1	151	157	PF00069	0.631
MOD_CK1_1	243	249	PF00069	0.531
MOD_CK1_1	308	314	PF00069	0.686
MOD_CK1_1	316	322	PF00069	0.640
MOD_CK1_1	331	337	PF00069	0.548
MOD_CK1_1	349	355	PF00069	0.742
MOD_CK1_1	406	412	PF00069	0.566
MOD_CK1_1	416	422	PF00069	0.674
MOD_CK2_1	177	183	PF00069	0.531
MOD_CK2_1	198	204	PF00069	0.648
MOD_CK2_1	249	255	PF00069	0.520
MOD_CK2_1	316	322	PF00069	0.668
MOD_CK2_1	330	336	PF00069	0.663
MOD_CK2_1	340	346	PF00069	0.588
MOD_CK2_1	395	401	PF00069	0.403
MOD_CK2_1	52	58	PF00069	0.677
MOD_CK2_1	86	92	PF00069	0.588
MOD_GlcNHglycan	153	156	PF01048	0.807
MOD_GlcNHglycan	242	245	PF01048	0.714
MOD_GlcNHglycan	248	251	PF01048	0.558
MOD_GlcNHglycan	315	318	PF01048	0.630
MOD_GlcNHglycan	346	349	PF01048	0.795
MOD_GlcNHglycan	352	355	PF01048	0.592
MOD_GlcNHglycan	405	408	PF01048	0.613
MOD_GlcNHglycan	415	418	PF01048	0.676
MOD_GSK3_1	246	253	PF00069	0.621
MOD_GSK3_1	299	306	PF00069	0.633
MOD_GSK3_1	308	315	PF00069	0.737
MOD_GSK3_1	321	328	PF00069	0.783
MOD_GSK3_1	336	343	PF00069	0.573
MOD_GSK3_1	344	351	PF00069	0.644
MOD_GSK3_1	412	419	PF00069	0.589
MOD_GSK3_1	421	428	PF00069	0.326
MOD_GSK3_1	476	483	PF00069	0.542
MOD_N-GLC_1	111	116	PF02516	0.448
MOD_N-GLC_1	198	203	PF02516	0.560
MOD_N-GLC_1	308	313	PF02516	0.633
MOD_NEK2_1	1	6	PF00069	0.594
MOD_NEK2_1	305	310	PF00069	0.723
MOD_NEK2_1	421	426	PF00069	0.406
MOD_NEK2_1	73	78	PF00069	0.787
MOD_NEK2_2	135	140	PF00069	0.445
MOD_PIKK_1	158	164	PF00454	0.664
MOD_PK_1	3	9	PF00069	0.562
MOD_PKA_2	129	135	PF00069	0.443
MOD_PKA_2	22	28	PF00069	0.644
MOD_PKA_2	272	278	PF00069	0.549
MOD_PKA_2	35	41	PF00069	0.535
MOD_PKA_2	67	73	PF00069	0.577
MOD_PKA_2	87	93	PF00069	0.773
MOD_Plk_1	198	204	PF00069	0.577
MOD_Plk_1	421	427	PF00069	0.392
MOD_Plk_1	86	92	PF00069	0.588
MOD_Plk_2-3	87	93	PF00069	0.580
MOD_Plk_4	38	44	PF00069	0.570
MOD_Plk_4	395	401	PF00069	0.403
MOD_Plk_4	435	441	PF00069	0.389
MOD_Plk_4	513	519	PF00069	0.357
MOD_ProDKin_1	148	154	PF00069	0.570
MOD_ProDKin_1	299	305	PF00069	0.602
MOD_ProDKin_1	308	314	PF00069	0.698
MOD_ProDKin_1	340	346	PF00069	0.668
MOD_ProDKin_1	370	376	PF00069	0.490
MOD_ProDKin_1	441	447	PF00069	0.374
MOD_SUMO_rev_2	144	148	PF00179	0.477
TRG_DiLeu_BaLyEn_6	191	196	PF01217	0.487
TRG_ENDOCYTIC_2	203	206	PF00928	0.520
TRG_ENDOCYTIC_2	40	43	PF00928	0.690
TRG_ER_diArg_1	176	178	PF00400	0.501
TRG_ER_diArg_1	189	192	PF00400	0.506
TRG_ER_diArg_1	193	195	PF00400	0.475
TRG_ER_diArg_1	457	459	PF00400	0.424
TRG_Pf-PMV_PEXEL_1	193	197	PF00026	0.478
TRG_Pf-PMV_PEXEL_1	510	515	PF00026	0.510
TRG_Pf-PMV_PEXEL_1	77	82	PF00026	0.585

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PF55	Leptomonas seymouri	52%	98%
A0A3S7X722	Leishmania donovani	99%	100%
A4HLU4	Leishmania braziliensis	71%	100%
E9B470	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%
Q4Q3V6	Leishmania major	89%	100%