LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
MYND finger containing protein - putative
Species:
Leishmania infantum
UniProt:
E9AHP7_LEIIN
TriTrypDb:
LINF_330031800
Length:
1028

Annotations

Annotations by Jardim et al.

Metal Binding, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AHP7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHP7

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0005488 binding 1 7
GO:0043167 ion binding 2 7
GO:0043169 cation binding 3 7
GO:0046872 metal ion binding 4 7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 448 452 PF00656 0.671
CLV_C14_Caspase3-7 47 51 PF00656 0.649
CLV_C14_Caspase3-7 803 807 PF00656 0.604
CLV_C14_Caspase3-7 963 967 PF00656 0.678
CLV_NRD_NRD_1 256 258 PF00675 0.629
CLV_NRD_NRD_1 42 44 PF00675 0.585
CLV_NRD_NRD_1 552 554 PF00675 0.457
CLV_NRD_NRD_1 643 645 PF00675 0.323
CLV_NRD_NRD_1 681 683 PF00675 0.523
CLV_NRD_NRD_1 816 818 PF00675 0.548
CLV_PCSK_KEX2_1 255 257 PF00082 0.635
CLV_PCSK_KEX2_1 42 44 PF00082 0.530
CLV_PCSK_KEX2_1 552 554 PF00082 0.457
CLV_PCSK_KEX2_1 642 644 PF00082 0.323
CLV_PCSK_KEX2_1 661 663 PF00082 0.323
CLV_PCSK_KEX2_1 681 683 PF00082 0.566
CLV_PCSK_KEX2_1 816 818 PF00082 0.549
CLV_PCSK_PC1ET2_1 661 663 PF00082 0.413
CLV_PCSK_PC7_1 548 554 PF00082 0.504
CLV_PCSK_SKI1_1 114 118 PF00082 0.676
CLV_PCSK_SKI1_1 146 150 PF00082 0.429
CLV_PCSK_SKI1_1 430 434 PF00082 0.472
CLV_PCSK_SKI1_1 5 9 PF00082 0.561
CLV_PCSK_SKI1_1 644 648 PF00082 0.413
CLV_PCSK_SKI1_1 689 693 PF00082 0.580
CLV_PCSK_SKI1_1 703 707 PF00082 0.510
CLV_PCSK_SKI1_1 778 782 PF00082 0.580
CLV_PCSK_SKI1_1 817 821 PF00082 0.553
CLV_PCSK_SKI1_1 878 882 PF00082 0.553
CLV_PCSK_SKI1_1 973 977 PF00082 0.634
DEG_APCC_DBOX_1 145 153 PF00400 0.491
DEG_APCC_DBOX_1 482 490 PF00400 0.506
DEG_APCC_DBOX_1 777 785 PF00400 0.531
DOC_CKS1_1 1010 1015 PF01111 0.666
DOC_CKS1_1 503 508 PF01111 0.415
DOC_CKS1_1 690 695 PF01111 0.445
DOC_CKS1_1 824 829 PF01111 0.492
DOC_CYCLIN_RxL_1 143 151 PF00134 0.462
DOC_CYCLIN_yCln2_LP_2 150 156 PF00134 0.470
DOC_CYCLIN_yCln2_LP_2 409 415 PF00134 0.685
DOC_MAPK_gen_1 428 435 PF00069 0.337
DOC_MAPK_gen_1 642 648 PF00069 0.459
DOC_MAPK_RevD_3 622 636 PF00069 0.557
DOC_PP2B_LxvP_1 150 153 PF13499 0.494
DOC_PP2B_LxvP_1 409 412 PF13499 0.686
DOC_PP2B_LxvP_1 622 625 PF13499 0.543
DOC_PP4_FxxP_1 268 271 PF00568 0.600
DOC_PP4_FxxP_1 379 382 PF00568 0.429
DOC_USP7_MATH_1 126 130 PF00917 0.615
DOC_USP7_MATH_1 158 162 PF00917 0.522
DOC_USP7_MATH_1 190 194 PF00917 0.554
DOC_USP7_MATH_1 210 214 PF00917 0.516
DOC_USP7_MATH_1 300 304 PF00917 0.648
DOC_USP7_MATH_1 337 341 PF00917 0.628
DOC_USP7_MATH_1 523 527 PF00917 0.609
DOC_USP7_MATH_1 528 532 PF00917 0.548
DOC_USP7_MATH_1 611 615 PF00917 0.777
DOC_USP7_MATH_1 780 784 PF00917 0.528
DOC_USP7_MATH_1 819 823 PF00917 0.601
DOC_USP7_MATH_1 941 945 PF00917 0.550
DOC_USP7_MATH_1 959 963 PF00917 0.722
DOC_WW_Pin1_4 1009 1014 PF00397 0.633
DOC_WW_Pin1_4 267 272 PF00397 0.625
DOC_WW_Pin1_4 453 458 PF00397 0.671
DOC_WW_Pin1_4 502 507 PF00397 0.406
DOC_WW_Pin1_4 572 577 PF00397 0.484
DOC_WW_Pin1_4 689 694 PF00397 0.544
DOC_WW_Pin1_4 696 701 PF00397 0.492
DOC_WW_Pin1_4 741 746 PF00397 0.641
DOC_WW_Pin1_4 75 80 PF00397 0.592
DOC_WW_Pin1_4 823 828 PF00397 0.510
DOC_WW_Pin1_4 9 14 PF00397 0.587
DOC_WW_Pin1_4 965 970 PF00397 0.663
LIG_14-3-3_CanoR_1 339 349 PF00244 0.537
LIG_14-3-3_CanoR_1 52 56 PF00244 0.517
LIG_14-3-3_CanoR_1 610 616 PF00244 0.554
LIG_14-3-3_CanoR_1 703 711 PF00244 0.535
LIG_14-3-3_CanoR_1 718 727 PF00244 0.504
LIG_14-3-3_CanoR_1 816 825 PF00244 0.595
LIG_14-3-3_CanoR_1 878 884 PF00244 0.477
LIG_14-3-3_CanoR_1 931 939 PF00244 0.563
LIG_Actin_WH2_2 764 780 PF00022 0.434
LIG_APCC_ABBA_1 898 903 PF00400 0.547
LIG_BIR_II_1 1 5 PF00653 0.517
LIG_BIR_III_2 451 455 PF00653 0.637
LIG_BIR_III_4 964 968 PF00653 0.671
LIG_BRCT_BRCA1_1 248 252 PF00533 0.706
LIG_BRCT_BRCA1_1 264 268 PF00533 0.650
LIG_BRCT_BRCA1_1 782 786 PF00533 0.595
LIG_BRCT_BRCA1_1 800 804 PF00533 0.315
LIG_eIF4E_1 173 179 PF01652 0.494
LIG_eIF4E_1 429 435 PF01652 0.520
LIG_eIF4E_1 590 596 PF01652 0.534
LIG_EVH1_2 625 629 PF00568 0.469
LIG_FHA_1 1010 1016 PF00498 0.656
LIG_FHA_1 178 184 PF00498 0.527
LIG_FHA_1 19 25 PF00498 0.601
LIG_FHA_1 404 410 PF00498 0.707
LIG_FHA_1 519 525 PF00498 0.568
LIG_FHA_1 52 58 PF00498 0.504
LIG_FHA_1 619 625 PF00498 0.567
LIG_FHA_1 759 765 PF00498 0.557
LIG_FHA_1 827 833 PF00498 0.457
LIG_FHA_1 88 94 PF00498 0.494
LIG_FHA_1 893 899 PF00498 0.617
LIG_FHA_2 241 247 PF00498 0.671
LIG_FHA_2 279 285 PF00498 0.603
LIG_FHA_2 378 384 PF00498 0.506
LIG_FHA_2 491 497 PF00498 0.428
LIG_FHA_2 503 509 PF00498 0.497
LIG_FHA_2 567 573 PF00498 0.585
LIG_FHA_2 801 807 PF00498 0.543
LIG_FHA_2 83 89 PF00498 0.640
LIG_LIR_Apic_2 265 271 PF02991 0.629
LIG_LIR_Apic_2 377 382 PF02991 0.429
LIG_LIR_Apic_2 821 827 PF02991 0.583
LIG_LIR_Gen_1 375 382 PF02991 0.498
LIG_LIR_Gen_1 383 394 PF02991 0.589
LIG_LIR_Gen_1 88 99 PF02991 0.468
LIG_LIR_Nem_3 161 167 PF02991 0.459
LIG_LIR_Nem_3 225 231 PF02991 0.505
LIG_LIR_Nem_3 309 315 PF02991 0.495
LIG_LIR_Nem_3 32 37 PF02991 0.346
LIG_LIR_Nem_3 375 379 PF02991 0.501
LIG_LIR_Nem_3 383 389 PF02991 0.552
LIG_LIR_Nem_3 426 432 PF02991 0.475
LIG_LIR_Nem_3 516 522 PF02991 0.531
LIG_LIR_Nem_3 699 705 PF02991 0.597
LIG_LIR_Nem_3 88 94 PF02991 0.438
LIG_LYPXL_S_1 315 319 PF13949 0.526
LIG_LYPXL_yS_3 316 319 PF13949 0.529
LIG_NRBOX 144 150 PF00104 0.547
LIG_PCNA_PIPBox_1 1 10 PF02747 0.541
LIG_Pex14_1 312 316 PF04695 0.546
LIG_Pex14_1 91 95 PF04695 0.475
LIG_Pex14_2 58 62 PF04695 0.409
LIG_Pex14_2 976 980 PF04695 0.609
LIG_PTB_Apo_2 25 32 PF02174 0.538
LIG_PTB_Phospho_1 25 31 PF10480 0.545
LIG_REV1ctd_RIR_1 711 720 PF16727 0.460
LIG_SH2_CRK 327 331 PF00017 0.619
LIG_SH2_CRK 386 390 PF00017 0.608
LIG_SH2_CRK 551 555 PF00017 0.448
LIG_SH2_CRK 795 799 PF00017 0.482
LIG_SH2_CRK 96 100 PF00017 0.602
LIG_SH2_GRB2like 1014 1017 PF00017 0.569
LIG_SH2_NCK_1 386 390 PF00017 0.542
LIG_SH2_SRC 753 756 PF00017 0.541
LIG_SH2_STAP1 327 331 PF00017 0.494
LIG_SH2_STAP1 620 624 PF00017 0.553
LIG_SH2_STAT5 1014 1017 PF00017 0.495
LIG_SH2_STAT5 229 232 PF00017 0.499
LIG_SH2_STAT5 31 34 PF00017 0.426
LIG_SH2_STAT5 327 330 PF00017 0.472
LIG_SH2_STAT5 376 379 PF00017 0.489
LIG_SH2_STAT5 518 521 PF00017 0.443
LIG_SH2_STAT5 590 593 PF00017 0.522
LIG_SH2_STAT5 620 623 PF00017 0.422
LIG_SH2_STAT5 658 661 PF00017 0.323
LIG_SH2_STAT5 753 756 PF00017 0.541
LIG_SH2_STAT5 893 896 PF00017 0.459
LIG_SH2_STAT5 918 921 PF00017 0.493
LIG_SH2_STAT5 96 99 PF00017 0.558
LIG_SH3_3 1007 1013 PF00018 0.705
LIG_SH3_3 390 396 PF00018 0.641
LIG_SH3_3 409 415 PF00018 0.585
LIG_SH3_3 451 457 PF00018 0.559
LIG_SH3_3 570 576 PF00018 0.534
LIG_SH3_3 595 601 PF00018 0.556
LIG_SH3_3 687 693 PF00018 0.600
LIG_SH3_5 382 386 PF00018 0.509
LIG_SUMO_SIM_par_1 146 151 PF11976 0.450
LIG_SUMO_SIM_par_1 592 599 PF11976 0.579
LIG_TYR_ITIM 860 865 PF00017 0.627
LIG_TYR_ITIM 93 98 PF00017 0.534
LIG_TYR_ITSM 312 319 PF00017 0.350
LIG_UBA3_1 854 861 PF00899 0.508
LIG_WRC_WIRS_1 376 381 PF05994 0.397
LIG_WRC_WIRS_1 4 9 PF05994 0.560
LIG_WRC_WIRS_1 880 885 PF05994 0.454
MOD_CDK_SPK_2 75 80 PF00069 0.592
MOD_CDK_SPxK_1 13 19 PF00069 0.440
MOD_CDK_SPxxK_3 696 703 PF00069 0.516
MOD_CK1_1 1009 1015 PF00069 0.701
MOD_CK1_1 18 24 PF00069 0.589
MOD_CK1_1 263 269 PF00069 0.461
MOD_CK1_1 303 309 PF00069 0.504
MOD_CK1_1 340 346 PF00069 0.674
MOD_CK1_1 375 381 PF00069 0.507
MOD_CK1_1 424 430 PF00069 0.573
MOD_CK1_1 630 636 PF00069 0.564
MOD_CK1_1 712 718 PF00069 0.584
MOD_CK2_1 240 246 PF00069 0.547
MOD_CK2_1 278 284 PF00069 0.551
MOD_CK2_1 303 309 PF00069 0.649
MOD_CK2_1 326 332 PF00069 0.575
MOD_CK2_1 341 347 PF00069 0.633
MOD_CK2_1 377 383 PF00069 0.501
MOD_CK2_1 502 508 PF00069 0.410
MOD_CK2_1 566 572 PF00069 0.594
MOD_CK2_1 82 88 PF00069 0.730
MOD_Cter_Amidation 640 643 PF01082 0.358
MOD_DYRK1A_RPxSP_1 689 693 PF00069 0.445
MOD_GlcNHglycan 1006 1009 PF01048 0.741
MOD_GlcNHglycan 122 125 PF01048 0.731
MOD_GlcNHglycan 129 132 PF01048 0.720
MOD_GlcNHglycan 136 139 PF01048 0.494
MOD_GlcNHglycan 224 227 PF01048 0.569
MOD_GlcNHglycan 243 246 PF01048 0.510
MOD_GlcNHglycan 249 252 PF01048 0.632
MOD_GlcNHglycan 25 28 PF01048 0.571
MOD_GlcNHglycan 301 305 PF01048 0.535
MOD_GlcNHglycan 423 426 PF01048 0.671
MOD_GlcNHglycan 525 528 PF01048 0.562
MOD_GlcNHglycan 530 533 PF01048 0.552
MOD_GlcNHglycan 537 540 PF01048 0.503
MOD_GlcNHglycan 597 601 PF01048 0.596
MOD_GlcNHglycan 613 616 PF01048 0.773
MOD_GlcNHglycan 629 632 PF01048 0.485
MOD_GlcNHglycan 734 738 PF01048 0.511
MOD_GlcNHglycan 786 789 PF01048 0.553
MOD_GlcNHglycan 849 852 PF01048 0.564
MOD_GlcNHglycan 857 860 PF01048 0.582
MOD_GlcNHglycan 886 889 PF01048 0.504
MOD_GSK3_1 148 155 PF00069 0.563
MOD_GSK3_1 179 186 PF00069 0.421
MOD_GSK3_1 18 25 PF00069 0.491
MOD_GSK3_1 190 197 PF00069 0.460
MOD_GSK3_1 241 248 PF00069 0.692
MOD_GSK3_1 263 270 PF00069 0.597
MOD_GSK3_1 337 344 PF00069 0.693
MOD_GSK3_1 417 424 PF00069 0.765
MOD_GSK3_1 518 525 PF00069 0.565
MOD_GSK3_1 596 603 PF00069 0.613
MOD_GSK3_1 714 721 PF00069 0.504
MOD_GSK3_1 780 787 PF00069 0.539
MOD_GSK3_1 798 805 PF00069 0.330
MOD_GSK3_1 819 826 PF00069 0.524
MOD_GSK3_1 9 16 PF00069 0.583
MOD_GSK3_1 937 944 PF00069 0.550
MOD_GSK3_1 965 972 PF00069 0.700
MOD_GSK3_1 994 1001 PF00069 0.701
MOD_N-GLC_1 341 346 PF02516 0.564
MOD_N-GLC_2 936 938 PF02516 0.562
MOD_NEK2_1 134 139 PF00069 0.518
MOD_NEK2_1 148 153 PF00069 0.505
MOD_NEK2_1 179 184 PF00069 0.465
MOD_NEK2_1 277 282 PF00069 0.489
MOD_NEK2_1 3 8 PF00069 0.552
MOD_NEK2_1 318 323 PF00069 0.472
MOD_NEK2_1 326 331 PF00069 0.474
MOD_NEK2_1 417 422 PF00069 0.684
MOD_NEK2_1 490 495 PF00069 0.523
MOD_NEK2_1 571 576 PF00069 0.578
MOD_NEK2_1 589 594 PF00069 0.247
MOD_NEK2_1 695 700 PF00069 0.605
MOD_NEK2_1 714 719 PF00069 0.503
MOD_NEK2_1 784 789 PF00069 0.593
MOD_NEK2_1 913 918 PF00069 0.547
MOD_NEK2_1 94 99 PF00069 0.454
MOD_NEK2_1 994 999 PF00069 0.741
MOD_NEK2_2 311 316 PF00069 0.473
MOD_NEK2_2 618 623 PF00069 0.516
MOD_PIKK_1 337 343 PF00454 0.664
MOD_PIKK_1 555 561 PF00454 0.473
MOD_PIKK_1 590 596 PF00454 0.534
MOD_PKA_1 552 558 PF00069 0.491
MOD_PKA_2 120 126 PF00069 0.752
MOD_PKA_2 158 164 PF00069 0.360
MOD_PKA_2 222 228 PF00069 0.521
MOD_PKA_2 51 57 PF00069 0.513
MOD_PKA_2 552 558 PF00069 0.491
MOD_PKA_2 855 861 PF00069 0.541
MOD_PKA_2 994 1000 PF00069 0.676
MOD_Plk_1 471 477 PF00069 0.465
MOD_Plk_1 490 496 PF00069 0.390
MOD_Plk_1 914 920 PF00069 0.477
MOD_Plk_2-3 82 88 PF00069 0.581
MOD_Plk_2-3 960 966 PF00069 0.696
MOD_Plk_4 1006 1012 PF00069 0.659
MOD_Plk_4 152 158 PF00069 0.564
MOD_Plk_4 179 185 PF00069 0.540
MOD_Plk_4 263 269 PF00069 0.513
MOD_Plk_4 3 9 PF00069 0.564
MOD_Plk_4 326 332 PF00069 0.557
MOD_Plk_4 709 715 PF00069 0.481
MOD_Plk_4 722 728 PF00069 0.339
MOD_Plk_4 819 825 PF00069 0.596
MOD_Plk_4 889 895 PF00069 0.503
MOD_Plk_4 914 920 PF00069 0.442
MOD_Plk_4 94 100 PF00069 0.514
MOD_ProDKin_1 1009 1015 PF00069 0.627
MOD_ProDKin_1 267 273 PF00069 0.625
MOD_ProDKin_1 453 459 PF00069 0.665
MOD_ProDKin_1 502 508 PF00069 0.410
MOD_ProDKin_1 572 578 PF00069 0.486
MOD_ProDKin_1 689 695 PF00069 0.546
MOD_ProDKin_1 696 702 PF00069 0.479
MOD_ProDKin_1 741 747 PF00069 0.641
MOD_ProDKin_1 75 81 PF00069 0.590
MOD_ProDKin_1 823 829 PF00069 0.517
MOD_ProDKin_1 9 15 PF00069 0.583
MOD_ProDKin_1 965 971 PF00069 0.659
MOD_SUMO_rev_2 107 116 PF00179 0.587
MOD_SUMO_rev_2 670 679 PF00179 0.393
MOD_SUMO_rev_2 744 751 PF00179 0.549
TRG_DiLeu_BaEn_1 174 179 PF01217 0.545
TRG_DiLeu_BaEn_2 236 242 PF01217 0.509
TRG_ENDOCYTIC_2 173 176 PF00928 0.505
TRG_ENDOCYTIC_2 228 231 PF00928 0.532
TRG_ENDOCYTIC_2 316 319 PF00928 0.483
TRG_ENDOCYTIC_2 327 330 PF00928 0.551
TRG_ENDOCYTIC_2 376 379 PF00928 0.489
TRG_ENDOCYTIC_2 386 389 PF00928 0.555
TRG_ENDOCYTIC_2 429 432 PF00928 0.484
TRG_ENDOCYTIC_2 795 798 PF00928 0.479
TRG_ENDOCYTIC_2 862 865 PF00928 0.530
TRG_ENDOCYTIC_2 95 98 PF00928 0.568
TRG_ER_diArg_1 255 257 PF00400 0.573
TRG_ER_diArg_1 41 43 PF00400 0.573
TRG_ER_diArg_1 551 553 PF00400 0.454
TRG_ER_diArg_1 642 644 PF00400 0.323
TRG_ER_diArg_1 680 682 PF00400 0.566
TRG_ER_diArg_1 815 817 PF00400 0.522
TRG_Pf-PMV_PEXEL_1 684 688 PF00026 0.535
TRG_Pf-PMV_PEXEL_1 769 774 PF00026 0.481

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P7B7 Leptomonas seymouri 44% 100%
A0A1X0P408 Trypanosomatidae 30% 100%
A0A3Q8IDX1 Leishmania donovani 99% 100%
A4HLU1 Leishmania braziliensis 74% 100%
D0A686 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
E9B467 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 99%
Q4Q3V9 Leishmania major 91% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS