LeishMANIAdb
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Kinesin motor domain-containing protein

Quick info Annotations Function or PPIs Localization Abundance Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Kinesin motor domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
E9AHP6_LEIIN
TriTrypDb:
LINF_330031700 *
Length:
540

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 15
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Abundance

Amastigote (protein)
Source Evidence on protein Close homologs
Pescher et al. (upgregulation) no yes: 0
Promastigote and amastigote
Source Evidence on protein Close homologs
Lahav et al.
- mRNA
- Protein

Expansion

Sequence features

E9AHP6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHP6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 23 27 PF00656 0.507
CLV_C14_Caspase3-7 51 55 PF00656 0.466
CLV_NRD_NRD_1 505 507 PF00675 0.410
CLV_PCSK_FUR_1 526 530 PF00082 0.470
CLV_PCSK_KEX2_1 504 506 PF00082 0.398
CLV_PCSK_KEX2_1 528 530 PF00082 0.472
CLV_PCSK_PC1ET2_1 528 530 PF00082 0.472
CLV_PCSK_PC7_1 501 507 PF00082 0.390
CLV_PCSK_SKI1_1 110 114 PF00082 0.603
CLV_PCSK_SKI1_1 476 480 PF00082 0.390
DEG_APCC_DBOX_1 100 108 PF00400 0.422
DEG_SPOP_SBC_1 45 49 PF00917 0.551
DOC_CYCLIN_RxL_1 117 125 PF00134 0.461
DOC_MAPK_MEF2A_6 8 16 PF00069 0.532
DOC_USP7_MATH_1 111 115 PF00917 0.542
DOC_USP7_MATH_1 141 145 PF00917 0.550
DOC_USP7_MATH_1 180 184 PF00917 0.590
DOC_USP7_MATH_1 219 223 PF00917 0.449
DOC_USP7_MATH_1 258 262 PF00917 0.396
DOC_USP7_MATH_1 28 32 PF00917 0.526
DOC_USP7_MATH_1 297 301 PF00917 0.401
DOC_USP7_MATH_1 336 340 PF00917 0.409
DOC_USP7_MATH_1 375 379 PF00917 0.428
DOC_USP7_MATH_1 466 470 PF00917 0.340
DOC_USP7_UBL2_3 438 442 PF12436 0.509
DOC_WW_Pin1_4 8 13 PF00397 0.527
LIG_14-3-3_CanoR_1 39 46 PF00244 0.556
LIG_14-3-3_CanoR_1 529 534 PF00244 0.453
LIG_14-3-3_CanoR_1 84 89 PF00244 0.514
LIG_BIR_II_1 1 5 PF00653 0.499
LIG_CaM_IQ_9 450 466 PF13499 0.343
LIG_FHA_1 117 123 PF00498 0.542
LIG_FHA_1 511 517 PF00498 0.421
LIG_FHA_2 111 117 PF00498 0.503
LIG_FHA_2 51 57 PF00498 0.456
LIG_GBD_Chelix_1 449 457 PF00786 0.423
LIG_LIR_Gen_1 56 66 PF02991 0.376
LIG_LIR_Nem_3 56 61 PF02991 0.439
LIG_NRBOX 511 517 PF00104 0.462
LIG_SH2_CRK 58 62 PF00017 0.423
LIG_SH2_GRB2like 58 61 PF00017 0.384
LIG_SH2_STAT5 33 36 PF00017 0.565
LIG_SH3_3 11 17 PF00018 0.646
LIG_SH3_3 420 426 PF00018 0.507
LIG_SUMO_SIM_anti_2 96 101 PF11976 0.352
LIG_TRAF2_1 517 520 PF00917 0.548
LIG_UBA3_1 72 78 PF00899 0.325
MOD_CAAXbox 537 540 PF01239 0.503
MOD_CK1_1 29 35 PF00069 0.567
MOD_CK1_1 38 44 PF00069 0.738
MOD_CK1_1 47 53 PF00069 0.597
MOD_CK2_1 110 116 PF00069 0.497
MOD_CK2_1 141 147 PF00069 0.408
MOD_CK2_1 180 186 PF00069 0.397
MOD_CK2_1 219 225 PF00069 0.525
MOD_CK2_1 258 264 PF00069 0.400
MOD_CK2_1 297 303 PF00069 0.404
MOD_CK2_1 336 342 PF00069 0.411
MOD_CK2_1 375 381 PF00069 0.432
MOD_CK2_1 50 56 PF00069 0.469
MOD_GlcNHglycan 1 4 PF01048 0.550
MOD_GlcNHglycan 144 147 PF01048 0.475
MOD_GlcNHglycan 183 186 PF01048 0.388
MOD_GlcNHglycan 222 225 PF01048 0.476
MOD_GlcNHglycan 26 29 PF01048 0.514
MOD_GlcNHglycan 261 264 PF01048 0.393
MOD_GlcNHglycan 300 303 PF01048 0.367
MOD_GlcNHglycan 339 342 PF01048 0.374
MOD_GlcNHglycan 378 381 PF01048 0.395
MOD_GlcNHglycan 41 44 PF01048 0.620
MOD_GlcNHglycan 427 430 PF01048 0.527
MOD_GlcNHglycan 50 53 PF01048 0.554
MOD_GlcNHglycan 520 523 PF01048 0.511
MOD_GSK3_1 20 27 PF00069 0.551
MOD_GSK3_1 28 35 PF00069 0.532
MOD_GSK3_1 37 44 PF00069 0.569
MOD_GSK3_1 46 53 PF00069 0.464
MOD_GSK3_1 518 525 PF00069 0.516
MOD_LATS_1 37 43 PF00433 0.521
MOD_N-GLC_1 24 29 PF02516 0.718
MOD_NEK2_1 411 416 PF00069 0.364
MOD_NEK2_1 427 432 PF00069 0.422
MOD_NEK2_1 453 458 PF00069 0.337
MOD_NEK2_1 82 87 PF00069 0.628
MOD_PIKK_1 26 32 PF00454 0.560
MOD_PKA_2 38 44 PF00069 0.518
MOD_PKA_2 83 89 PF00069 0.596
MOD_Plk_1 20 26 PF00069 0.675
MOD_Plk_1 411 417 PF00069 0.366
MOD_Plk_2-3 20 26 PF00069 0.510
MOD_Plk_4 41 47 PF00069 0.556
MOD_ProDKin_1 8 14 PF00069 0.528
MOD_SUMO_for_1 61 64 PF00179 0.416
MOD_SUMO_rev_2 473 480 PF00179 0.331
TRG_DiLeu_BaEn_1 511 516 PF01217 0.500
TRG_ENDOCYTIC_2 58 61 PF00928 0.425
TRG_ENDOCYTIC_2 79 82 PF00928 0.613
TRG_ER_diArg_1 468 471 PF00400 0.344
TRG_ER_diArg_1 503 506 PF00400 0.396
TRG_NLS_MonoExtN_4 526 532 PF00514 0.463
TRG_Pf-PMV_PEXEL_1 120 125 PF00026 0.451

Homologs

Protein Taxonomy Sequence identity Coverage
E9B466 Leishmania mexicana (strain MHOM/GT/2001/U1103) 76% 67%
Q4Q3W0 Leishmania major 83% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS