CRAL-TRIO domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AHP2_LEIIN

TriTrypDb:

LINF_330031300

Length:

648

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AHP2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHP2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	138	142	PF00656	0.665
CLV_C14_Caspase3-7	179	183	PF00656	0.650
CLV_C14_Caspase3-7	268	272	PF00656	0.633
CLV_C14_Caspase3-7	382	386	PF00656	0.672
CLV_C14_Caspase3-7	400	404	PF00656	0.648
CLV_C14_Caspase3-7	49	53	PF00656	0.637
CLV_C14_Caspase3-7	515	519	PF00656	0.551
CLV_NRD_NRD_1	343	345	PF00675	0.669
CLV_NRD_NRD_1	55	57	PF00675	0.763
CLV_NRD_NRD_1	638	640	PF00675	0.556
CLV_PCSK_FUR_1	340	344	PF00082	0.769
CLV_PCSK_KEX2_1	342	344	PF00082	0.752
CLV_PCSK_KEX2_1	55	57	PF00082	0.763
CLV_PCSK_KEX2_1	638	640	PF00082	0.547
CLV_PCSK_SKI1_1	154	158	PF00082	0.680
CLV_PCSK_SKI1_1	229	233	PF00082	0.765
DEG_SCF_FBW7_1	98	105	PF00400	0.762
DEG_SCF_FBW7_2	612	619	PF00400	0.601
DEG_SPOP_SBC_1	223	227	PF00917	0.734
DEG_SPOP_SBC_1	231	235	PF00917	0.652
DEG_SPOP_SBC_1	237	241	PF00917	0.598
DEG_SPOP_SBC_1	604	608	PF00917	0.470
DOC_ANK_TNKS_1	266	273	PF00023	0.638
DOC_ANK_TNKS_1	558	565	PF00023	0.455
DOC_CYCLIN_RxL_1	151	161	PF00134	0.691
DOC_MAPK_gen_1	307	316	PF00069	0.762
DOC_MAPK_gen_1	483	492	PF00069	0.449
DOC_MAPK_gen_1	596	604	PF00069	0.429
DOC_PP1_RVXF_1	175	181	PF00149	0.780
DOC_USP7_MATH_1	102	106	PF00917	0.770
DOC_USP7_MATH_1	148	152	PF00917	0.696
DOC_USP7_MATH_1	222	226	PF00917	0.736
DOC_USP7_MATH_1	231	235	PF00917	0.618
DOC_USP7_MATH_1	324	328	PF00917	0.670
DOC_USP7_MATH_1	39	43	PF00917	0.777
DOC_USP7_MATH_1	397	401	PF00917	0.686
DOC_USP7_MATH_1	62	66	PF00917	0.760
DOC_WW_Pin1_4	328	333	PF00397	0.788
DOC_WW_Pin1_4	528	533	PF00397	0.457
DOC_WW_Pin1_4	540	545	PF00397	0.473
DOC_WW_Pin1_4	612	617	PF00397	0.604
DOC_WW_Pin1_4	96	101	PF00397	0.679
LIG_14-3-3_CanoR_1	103	111	PF00244	0.689
LIG_14-3-3_CanoR_1	154	164	PF00244	0.731
LIG_14-3-3_CanoR_1	177	186	PF00244	0.779
LIG_14-3-3_CanoR_1	218	222	PF00244	0.752
LIG_14-3-3_CanoR_1	229	237	PF00244	0.627
LIG_14-3-3_CanoR_1	264	274	PF00244	0.772
LIG_14-3-3_CanoR_1	299	305	PF00244	0.629
LIG_14-3-3_CanoR_1	30	34	PF00244	0.653
LIG_14-3-3_CanoR_1	599	605	PF00244	0.430
LIG_14-3-3_CterR_2	644	648	PF00244	0.702
LIG_APCC_ABBA_1	537	542	PF00400	0.458
LIG_BIR_II_1	1	5	PF00653	0.736
LIG_BIR_III_2	403	407	PF00653	0.691
LIG_BIR_III_2	518	522	PF00653	0.429
LIG_BRCT_BRCA1_1	390	394	PF00533	0.557
LIG_BRCT_BRCA1_1	566	570	PF00533	0.420
LIG_deltaCOP1_diTrp_1	592	598	PF00928	0.424
LIG_eIF4E_1	452	458	PF01652	0.441
LIG_FHA_1	151	157	PF00498	0.694
LIG_FHA_1	173	179	PF00498	0.685
LIG_FHA_1	231	237	PF00498	0.729
LIG_FHA_1	283	289	PF00498	0.651
LIG_FHA_1	497	503	PF00498	0.473
LIG_FHA_1	99	105	PF00498	0.765
LIG_FHA_2	177	183	PF00498	0.651
LIG_FHA_2	185	191	PF00498	0.548
LIG_FHA_2	266	272	PF00498	0.712
LIG_FHA_2	299	305	PF00498	0.760
LIG_FHA_2	47	53	PF00498	0.644
LIG_FHA_2	506	512	PF00498	0.464
LIG_LIR_Gen_1	377	387	PF02991	0.619
LIG_LIR_Nem_3	456	461	PF02991	0.427
LIG_LIR_Nem_3	482	487	PF02991	0.532
LIG_LIR_Nem_3	534	540	PF02991	0.541
LIG_LIR_Nem_3	567	573	PF02991	0.449
LIG_LIR_Nem_3	595	601	PF02991	0.424
LIG_MYND_3	538	542	PF01753	0.550
LIG_Pex14_1	594	598	PF04695	0.417
LIG_Pex14_2	5	9	PF04695	0.749
LIG_Pex14_2	566	570	PF04695	0.420
LIG_Rb_LxCxE_1	543	563	PF01857	0.501
LIG_REV1ctd_RIR_1	482	490	PF16727	0.437
LIG_SH2_NCK_1	122	126	PF00017	0.781
LIG_SH2_NCK_1	571	575	PF00017	0.577
LIG_SH2_SRC	122	125	PF00017	0.655
LIG_SH2_STAP1	196	200	PF00017	0.622
LIG_SH2_STAP1	35	39	PF00017	0.780
LIG_SH2_STAT5	251	254	PF00017	0.727
LIG_SH2_STAT5	442	445	PF00017	0.511
LIG_SH2_STAT5	461	464	PF00017	0.281
LIG_SH3_3	115	121	PF00018	0.637
LIG_SH3_3	403	409	PF00018	0.598
LIG_SH3_3	94	100	PF00018	0.689
LIG_SUMO_SIM_anti_2	511	518	PF11976	0.575
LIG_SUMO_SIM_anti_2	580	585	PF11976	0.424
LIG_SUMO_SIM_par_1	505	512	PF11976	0.459
LIG_SUMO_SIM_par_1	600	608	PF11976	0.450
LIG_TRAF2_1	301	304	PF00917	0.753
LIG_TRAF2_1	331	334	PF00917	0.786
LIG_TYR_ITIM	459	464	PF00017	0.429
MOD_CDK_SPK_2	540	545	PF00069	0.556
MOD_CDK_SPK_2	98	103	PF00069	0.761
MOD_CDK_SPxxK_3	328	335	PF00069	0.786
MOD_CDK_SPxxK_3	96	103	PF00069	0.680
MOD_CK1_1	14	20	PF00069	0.672
MOD_CK1_1	160	166	PF00069	0.809
MOD_CK1_1	203	209	PF00069	0.761
MOD_CK1_1	328	334	PF00069	0.699
MOD_CK1_1	364	370	PF00069	0.788
MOD_CK1_1	543	549	PF00069	0.465
MOD_CK1_1	603	609	PF00069	0.477
MOD_CK1_1	61	67	PF00069	0.759
MOD_CK2_1	184	190	PF00069	0.631
MOD_CK2_1	298	304	PF00069	0.694
MOD_CK2_1	328	334	PF00069	0.786
MOD_CK2_1	390	396	PF00069	0.702
MOD_CK2_1	505	511	PF00069	0.507
MOD_Cter_Amidation	53	56	PF01082	0.632
MOD_GlcNHglycan	141	144	PF01048	0.721
MOD_GlcNHglycan	150	153	PF01048	0.708
MOD_GlcNHglycan	16	19	PF01048	0.753
MOD_GlcNHglycan	160	163	PF01048	0.485
MOD_GlcNHglycan	182	185	PF01048	0.701
MOD_GlcNHglycan	202	205	PF01048	0.708
MOD_GlcNHglycan	240	243	PF01048	0.723
MOD_GlcNHglycan	355	358	PF01048	0.733
MOD_GlcNHglycan	37	40	PF01048	0.707
MOD_GlcNHglycan	399	402	PF01048	0.688
MOD_GlcNHglycan	41	44	PF01048	0.676
MOD_GlcNHglycan	474	477	PF01048	0.550
MOD_GlcNHglycan	511	514	PF01048	0.590
MOD_GlcNHglycan	52	55	PF01048	0.637
MOD_GlcNHglycan	60	63	PF01048	0.469
MOD_GlcNHglycan	75	78	PF01048	0.533
MOD_GSK3_1	10	17	PF00069	0.673
MOD_GSK3_1	156	163	PF00069	0.752
MOD_GSK3_1	172	179	PF00069	0.693
MOD_GSK3_1	180	187	PF00069	0.759
MOD_GSK3_1	232	239	PF00069	0.642
MOD_GSK3_1	308	315	PF00069	0.637
MOD_GSK3_1	318	325	PF00069	0.667
MOD_GSK3_1	35	42	PF00069	0.700
MOD_GSK3_1	46	53	PF00069	0.702
MOD_GSK3_1	505	512	PF00069	0.514
MOD_GSK3_1	58	65	PF00069	0.659
MOD_GSK3_1	600	607	PF00069	0.438
MOD_GSK3_1	69	76	PF00069	0.649
MOD_GSK3_1	98	105	PF00069	0.650
MOD_N-GLC_1	11	16	PF02516	0.676
MOD_N-GLC_1	364	369	PF02516	0.703
MOD_N-GLC_1	50	55	PF02516	0.754
MOD_N-GLC_1	604	609	PF02516	0.481
MOD_N-GLC_1	66	71	PF02516	0.624
MOD_N-GLC_1	72	77	PF02516	0.684
MOD_NEK2_1	1	6	PF00069	0.703
MOD_NEK2_1	11	16	PF00069	0.616
MOD_NEK2_1	156	161	PF00069	0.760
MOD_NEK2_1	232	237	PF00069	0.773
MOD_NEK2_1	244	249	PF00069	0.578
MOD_NEK2_1	28	33	PF00069	0.684
MOD_NEK2_1	288	293	PF00069	0.702
MOD_NEK2_1	505	510	PF00069	0.444
MOD_NEK2_2	594	599	PF00069	0.425
MOD_PIKK_1	335	341	PF00454	0.797
MOD_PK_1	312	318	PF00069	0.678
MOD_PK_1	577	583	PF00069	0.540
MOD_PKA_2	102	108	PF00069	0.689
MOD_PKA_2	14	20	PF00069	0.672
MOD_PKA_2	176	182	PF00069	0.753
MOD_PKA_2	217	223	PF00069	0.767
MOD_PKA_2	266	272	PF00069	0.769
MOD_PKA_2	29	35	PF00069	0.688
MOD_PKA_2	298	304	PF00069	0.681
MOD_PKA_2	348	354	PF00069	0.709
MOD_PKA_2	39	45	PF00069	0.690
MOD_Plk_1	312	318	PF00069	0.725
MOD_Plk_1	325	331	PF00069	0.683
MOD_Plk_1	388	394	PF00069	0.706
MOD_Plk_1	604	610	PF00069	0.498
MOD_Plk_1	66	72	PF00069	0.678
MOD_Plk_2-3	298	304	PF00069	0.644
MOD_Plk_2-3	379	385	PF00069	0.673
MOD_Plk_2-3	390	396	PF00069	0.696
MOD_Plk_4	1	7	PF00069	0.736
MOD_Plk_4	195	201	PF00069	0.619
MOD_Plk_4	232	238	PF00069	0.687
MOD_Plk_4	312	318	PF00069	0.547
MOD_Plk_4	543	549	PF00069	0.433
MOD_Plk_4	605	611	PF00069	0.523
MOD_Plk_4	66	72	PF00069	0.762
MOD_ProDKin_1	328	334	PF00069	0.786
MOD_ProDKin_1	528	534	PF00069	0.454
MOD_ProDKin_1	540	546	PF00069	0.470
MOD_ProDKin_1	612	618	PF00069	0.602
MOD_ProDKin_1	96	102	PF00069	0.680
MOD_SUMO_rev_2	582	591	PF00179	0.534
TRG_DiLeu_BaEn_2	466	472	PF01217	0.432
TRG_ENDOCYTIC_2	446	449	PF00928	0.438
TRG_ENDOCYTIC_2	461	464	PF00928	0.366
TRG_ENDOCYTIC_2	57	60	PF00928	0.675
TRG_ER_diArg_1	294	297	PF00400	0.787
TRG_ER_diArg_1	340	343	PF00400	0.763
TRG_ER_diArg_1	485	488	PF00400	0.427
TRG_ER_diArg_1	55	57	PF00400	0.763
TRG_ER_diArg_1	557	560	PF00400	0.482
TRG_ER_diArg_1	642	645	PF00400	0.549
TRG_Pf-PMV_PEXEL_1	414	418	PF00026	0.712
TRG_Pf-PMV_PEXEL_1	447	451	PF00026	0.484

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILQ5	Leptomonas seymouri	49%	100%
A0A3Q8IKB2	Leishmania donovani	99%	100%