DUF3402 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AHN7_LEIIN

TriTrypDb:

LINF_330027300

Length:

272

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AHN7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHN7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	136	140	PF00656	0.544
CLV_C14_Caspase3-7	3	7	PF00656	0.412
CLV_C14_Caspase3-7	77	81	PF00656	0.494
CLV_NRD_NRD_1	62	64	PF00675	0.550
CLV_NRD_NRD_1	72	74	PF00675	0.484
CLV_PCSK_KEX2_1	62	64	PF00082	0.550
CLV_PCSK_KEX2_1	72	74	PF00082	0.484
CLV_PCSK_SKI1_1	186	190	PF00082	0.624
CLV_PCSK_SKI1_1	246	250	PF00082	0.550
CLV_PCSK_SKI1_1	62	66	PF00082	0.570
CLV_PCSK_SKI1_1	72	76	PF00082	0.657
DOC_CDC14_PxL_1	231	239	PF14671	0.586
DOC_CYCLIN_RxL_1	183	192	PF00134	0.488
DOC_MAPK_gen_1	105	112	PF00069	0.473
DOC_PP1_RVXF_1	130	136	PF00149	0.544
DOC_USP7_MATH_1	137	141	PF00917	0.574
DOC_USP7_MATH_1	159	163	PF00917	0.668
DOC_USP7_MATH_1	224	228	PF00917	0.552
LIG_14-3-3_CanoR_1	130	136	PF00244	0.589
LIG_14-3-3_CanoR_1	221	231	PF00244	0.643
LIG_14-3-3_CanoR_1	255	263	PF00244	0.512
LIG_14-3-3_CanoR_1	54	61	PF00244	0.519
LIG_14-3-3_CterR_2	269	272	PF00244	0.583
LIG_BIR_II_1	1	5	PF00653	0.499
LIG_BRCT_BRCA1_1	216	220	PF00533	0.475
LIG_CaM_IQ_9	253	268	PF13499	0.463
LIG_deltaCOP1_diTrp_1	6	14	PF00928	0.469
LIG_FHA_1	117	123	PF00498	0.538
LIG_FHA_2	38	44	PF00498	0.519
LIG_LIR_Gen_1	115	125	PF02991	0.579
LIG_LIR_Gen_1	134	143	PF02991	0.521
LIG_LIR_LC3C_4	97	100	PF02991	0.453
LIG_LIR_Nem_3	115	121	PF02991	0.520
LIG_LIR_Nem_3	134	138	PF02991	0.519
LIG_LIR_Nem_3	217	223	PF02991	0.560
LIG_LIR_Nem_3	258	263	PF02991	0.543
LIG_LIR_Nem_3	40	45	PF02991	0.583
LIG_LIR_Nem_3	6	11	PF02991	0.554
LIG_LIR_Nem_3	81	87	PF02991	0.510
LIG_SH2_STAP1	114	118	PF00017	0.559
LIG_SH2_STAT5	114	117	PF00017	0.484
LIG_SH2_STAT5	166	169	PF00017	0.602
LIG_SH2_STAT5	38	41	PF00017	0.405
LIG_Sin3_3	208	215	PF02671	0.468
LIG_SUMO_SIM_par_1	210	218	PF11976	0.552
LIG_UBA3_1	211	219	PF00899	0.571
LIG_WRC_WIRS_1	220	225	PF05994	0.530
MOD_CK1_1	222	228	PF00069	0.681
MOD_CK2_1	114	120	PF00069	0.570
MOD_CK2_1	37	43	PF00069	0.535
MOD_GlcNHglycan	16	19	PF01048	0.596
MOD_GlcNHglycan	174	177	PF01048	0.644
MOD_GlcNHglycan	224	227	PF01048	0.674
MOD_GlcNHglycan	250	254	PF01048	0.418
MOD_GlcNHglycan	257	260	PF01048	0.330
MOD_GSK3_1	112	119	PF00069	0.575
MOD_GSK3_1	164	171	PF00069	0.645
MOD_GSK3_1	236	243	PF00069	0.544
MOD_GSK3_1	251	258	PF00069	0.538
MOD_NEK2_1	14	19	PF00069	0.594
MOD_NEK2_1	158	163	PF00069	0.666
MOD_NEK2_1	241	246	PF00069	0.524
MOD_NEK2_1	249	254	PF00069	0.347
MOD_NEK2_2	181	186	PF00069	0.507
MOD_PKA_2	131	137	PF00069	0.585
MOD_PKA_2	159	165	PF00069	0.671
MOD_PKA_2	53	59	PF00069	0.482
MOD_Plk_1	168	174	PF00069	0.564
MOD_Plk_1	88	94	PF00069	0.436
MOD_Plk_2-3	37	43	PF00069	0.524
MOD_Plk_2-3	4	10	PF00069	0.381
MOD_SUMO_rev_2	97	106	PF00179	0.447
TRG_DiLeu_BaEn_1	60	65	PF01217	0.628
TRG_DiLeu_BaEn_2	69	75	PF01217	0.578
TRG_DiLeu_BaEn_4	70	76	PF01217	0.485
TRG_DiLeu_BaLyEn_6	229	234	PF01217	0.539
TRG_DiLeu_LyEn_5	60	65	PF01217	0.509
TRG_ENDOCYTIC_2	11	14	PF00928	0.509
TRG_ENDOCYTIC_2	125	128	PF00928	0.543
TRG_ENDOCYTIC_2	42	45	PF00928	0.525
TRG_ER_diArg_1	130	133	PF00400	0.541
TRG_ER_diArg_1	263	266	PF00400	0.470
TRG_ER_diArg_1	268	271	PF00400	0.506
TRG_ER_diArg_1	61	63	PF00400	0.584
TRG_ER_diArg_1	72	74	PF00400	0.474
TRG_Pf-PMV_PEXEL_1	186	191	PF00026	0.585
TRG_Pf-PMV_PEXEL_1	232	236	PF00026	0.471
TRG_Pf-PMV_PEXEL_1	62	67	PF00026	0.571
TRG_Pf-PMV_PEXEL_1	73	77	PF00026	0.577

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0P3M6	Trypanosomatidae	28%	97%
A0A3R7ME57	Trypanosoma rangeli	29%	96%
A0A3S7X6V8	Leishmania donovani	100%	100%
A4HLP9	Leishmania braziliensis	71%	100%
D0A6C5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	98%
E9B424	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%
Q4Q400	Leishmania major	93%	100%
V5BTW6	Trypanosoma cruzi	31%	97%