Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

Protein of unknown function (DUF2946), putative

Species:

Leishmania infantum

UniProt:

E9AHI8_LEIIN

TriTrypDb:

Length:

158

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

E9AHI8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHI8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	148	152	PF00082	0.535
DOC_MAPK_FxFP_2	90	93	PF00069	0.385
DOC_PP1_RVXF_1	146	153	PF00149	0.331
DOC_PP4_FxxP_1	90	93	PF00568	0.385
DOC_WW_Pin1_4	11	16	PF00397	0.580
LIG_14-3-3_CanoR_1	10	15	PF00244	0.580
LIG_14-3-3_CanoR_1	119	124	PF00244	0.581
LIG_14-3-3_CanoR_1	76	82	PF00244	0.199
LIG_Actin_WH2_2	48	65	PF00022	0.199
LIG_BIR_II_1	1	5	PF00653	0.587
LIG_BIR_III_1	1	5	PF00653	0.587
LIG_BIR_III_3	1	5	PF00653	0.587
LIG_BRCT_BRCA1_1	48	52	PF00533	0.199
LIG_FHA_1	70	76	PF00498	0.199
LIG_FHA_1	96	102	PF00498	0.568
LIG_LIR_Apic_2	88	93	PF02991	0.199
LIG_LIR_Gen_1	49	59	PF02991	0.199
LIG_LIR_Nem_3	48	54	PF02991	0.199
LIG_LIR_Nem_3	88	92	PF02991	0.199
LIG_MLH1_MIPbox_1	48	52	PF16413	0.199
LIG_Pex14_2	64	68	PF04695	0.321
LIG_SH2_STAT5	44	47	PF00017	0.199
LIG_SH3_3	23	29	PF00018	0.576
LIG_WRC_WIRS_1	86	91	PF05994	0.199
MOD_CK1_1	127	133	PF00069	0.199
MOD_CK1_1	13	19	PF00069	0.583
MOD_CK1_1	66	72	PF00069	0.318
MOD_CK1_1	80	86	PF00069	0.199
MOD_CK1_1	88	94	PF00069	0.199
MOD_CK2_1	109	115	PF00069	0.587
MOD_GlcNHglycan	126	129	PF01048	0.199
MOD_GlcNHglycan	139	142	PF01048	0.199
MOD_GlcNHglycan	77	80	PF01048	0.199
MOD_GSK3_1	62	69	PF00069	0.318
MOD_GSK3_1	88	95	PF00069	0.386
MOD_GSK3_1	9	16	PF00069	0.582
MOD_LATS_1	106	112	PF00433	0.580
MOD_N-GLC_1	109	114	PF02516	0.385
MOD_N-GLC_1	119	124	PF02516	0.381
MOD_NEK2_1	109	114	PF00069	0.585
MOD_NEK2_1	139	144	PF00069	0.396
MOD_NEK2_1	20	25	PF00069	0.586
MOD_NEK2_1	45	50	PF00069	0.199
MOD_NEK2_1	62	67	PF00069	0.313
MOD_NEK2_1	75	80	PF00069	0.199
MOD_NEK2_1	85	90	PF00069	0.199
MOD_PIKK_1	139	145	PF00454	0.396
MOD_PIKK_1	92	98	PF00454	0.551
MOD_PKA_2	75	81	PF00069	0.199
MOD_PKA_2	9	15	PF00069	0.582
MOD_Plk_1	119	125	PF00069	0.400
MOD_Plk_4	46	52	PF00069	0.199
MOD_Plk_4	80	86	PF00069	0.199
MOD_Plk_4	96	102	PF00069	0.568
MOD_ProDKin_1	11	17	PF00069	0.581
TRG_DiLeu_BaLyEn_6	129	134	PF01217	0.199