Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AHI3_LEIIN

TriTrypDb:

LINF_290013800

Length:

459

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AHI3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHI3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	106	110	PF00656	0.474
CLV_NRD_NRD_1	204	206	PF00675	0.604
CLV_NRD_NRD_1	348	350	PF00675	0.636
CLV_PCSK_KEX2_1	204	206	PF00082	0.593
CLV_PCSK_PC7_1	200	206	PF00082	0.614
CLV_PCSK_SKI1_1	236	240	PF00082	0.670
CLV_PCSK_SKI1_1	366	370	PF00082	0.621
CLV_PCSK_SKI1_1	387	391	PF00082	0.618
CLV_PCSK_SKI1_1	418	422	PF00082	0.621
DEG_Nend_UBRbox_3	1	3	PF02207	0.675
DEG_SPOP_SBC_1	24	28	PF00917	0.746
DOC_CKS1_1	404	409	PF01111	0.760
DOC_CYCLIN_RxL_1	353	365	PF00134	0.697
DOC_MAPK_MEF2A_6	88	97	PF00069	0.416
DOC_PP1_RVXF_1	364	371	PF00149	0.739
DOC_PP2B_LxvP_1	361	364	PF13499	0.746
DOC_PP2B_LxvP_1	412	415	PF13499	0.643
DOC_PP2B_LxvP_1	55	58	PF13499	0.599
DOC_SPAK_OSR1_1	290	294	PF12202	0.440
DOC_USP7_MATH_1	186	190	PF00917	0.561
DOC_USP7_MATH_1	209	213	PF00917	0.642
DOC_USP7_MATH_1	23	27	PF00917	0.752
DOC_USP7_MATH_1	237	241	PF00917	0.621
DOC_USP7_MATH_1	389	393	PF00917	0.652
DOC_USP7_MATH_1	427	431	PF00917	0.554
DOC_USP7_MATH_1	51	55	PF00917	0.605
DOC_WW_Pin1_4	203	208	PF00397	0.721
DOC_WW_Pin1_4	224	229	PF00397	0.689
DOC_WW_Pin1_4	231	236	PF00397	0.633
DOC_WW_Pin1_4	25	30	PF00397	0.758
DOC_WW_Pin1_4	295	300	PF00397	0.585
DOC_WW_Pin1_4	317	322	PF00397	0.609
DOC_WW_Pin1_4	336	341	PF00397	0.523
DOC_WW_Pin1_4	397	402	PF00397	0.674
DOC_WW_Pin1_4	403	408	PF00397	0.654
DOC_WW_Pin1_4	71	76	PF00397	0.775
LIG_14-3-3_CanoR_1	236	242	PF00244	0.674
LIG_14-3-3_CanoR_1	366	371	PF00244	0.689
LIG_14-3-3_CanoR_1	46	51	PF00244	0.573
LIG_Actin_WH2_2	2	20	PF00022	0.681
LIG_BRCT_BRCA1_1	272	276	PF00533	0.452
LIG_BRCT_BRCA1_1	427	431	PF00533	0.508
LIG_FHA_1	12	18	PF00498	0.663
LIG_FHA_1	158	164	PF00498	0.533
LIG_FHA_1	224	230	PF00498	0.628
LIG_FHA_1	280	286	PF00498	0.586
LIG_FHA_1	298	304	PF00498	0.489
LIG_FHA_1	36	42	PF00498	0.724
LIG_FHA_1	445	451	PF00498	0.601
LIG_FHA_1	59	65	PF00498	0.727
LIG_FHA_1	92	98	PF00498	0.402
LIG_FHA_2	321	327	PF00498	0.632
LIG_FHA_2	367	373	PF00498	0.741
LIG_FHA_2	47	53	PF00498	0.552
LIG_FHA_2	76	82	PF00498	0.745
LIG_LIR_Gen_1	282	291	PF02991	0.533
LIG_LIR_Nem_3	273	279	PF02991	0.483
LIG_LIR_Nem_3	282	286	PF02991	0.425
LIG_MYND_1	411	415	PF01753	0.568
LIG_RPA_C_Fungi	285	297	PF08784	0.507
LIG_SH2_NCK_1	48	52	PF00017	0.569
LIG_SH2_STAP1	256	260	PF00017	0.405
LIG_SH2_STAP1	279	283	PF00017	0.463
LIG_SH2_STAT5	48	51	PF00017	0.551
LIG_SH3_3	298	304	PF00018	0.622
LIG_SH3_3	313	319	PF00018	0.636
LIG_SH3_3	398	404	PF00018	0.666
LIG_SH3_3	405	411	PF00018	0.645
LIG_SUMO_SIM_anti_2	320	326	PF11976	0.627
LIG_SUMO_SIM_par_1	320	326	PF11976	0.627
LIG_TRAF2_1	115	118	PF00917	0.614
LIG_TRAF2_1	179	182	PF00917	0.525
MOD_CDK_SPK_2	231	236	PF00069	0.706
MOD_CK1_1	111	117	PF00069	0.551
MOD_CK1_1	154	160	PF00069	0.638
MOD_CK1_1	212	218	PF00069	0.618
MOD_CK1_1	295	301	PF00069	0.589
MOD_CK1_1	306	312	PF00069	0.657
MOD_CK1_1	320	326	PF00069	0.592
MOD_CK1_1	36	42	PF00069	0.770
MOD_CK1_1	56	62	PF00069	0.484
MOD_CK2_1	112	118	PF00069	0.601
MOD_CK2_1	366	372	PF00069	0.742
MOD_CK2_1	46	52	PF00069	0.552
MOD_CK2_1	73	79	PF00069	0.790
MOD_DYRK1A_RPxSP_1	297	301	PF00069	0.614
MOD_GlcNHglycan	216	220	PF01048	0.703
MOD_GlcNHglycan	239	242	PF01048	0.769
MOD_GlcNHglycan	255	259	PF01048	0.367
MOD_GlcNHglycan	294	297	PF01048	0.621
MOD_GlcNHglycan	433	436	PF01048	0.478
MOD_GSK3_1	103	110	PF00069	0.527
MOD_GSK3_1	295	302	PF00069	0.733
MOD_GSK3_1	327	334	PF00069	0.593
MOD_GSK3_1	33	40	PF00069	0.763
MOD_GSK3_1	362	369	PF00069	0.642
MOD_GSK3_1	376	383	PF00069	0.611
MOD_GSK3_1	427	434	PF00069	0.536
MOD_GSK3_1	46	53	PF00069	0.556
MOD_GSK3_1	56	63	PF00069	0.622
MOD_GSK3_1	66	73	PF00069	0.674
MOD_GSK3_1	75	82	PF00069	0.578
MOD_N-GLC_1	231	236	PF02516	0.658
MOD_N-GLC_1	327	332	PF02516	0.595
MOD_N-GLC_2	246	248	PF02516	0.592
MOD_NEK2_1	108	113	PF00069	0.457
MOD_NEK2_1	223	228	PF00069	0.650
MOD_NEK2_1	230	235	PF00069	0.660
MOD_NEK2_1	292	297	PF00069	0.509
MOD_NEK2_1	327	332	PF00069	0.595
MOD_NEK2_1	425	430	PF00069	0.583
MOD_NEK2_1	97	102	PF00069	0.436
MOD_PIKK_1	103	109	PF00454	0.477
MOD_PIKK_1	113	119	PF00454	0.509
MOD_PIKK_1	270	276	PF00454	0.443
MOD_PIKK_1	306	312	PF00454	0.712
MOD_PIKK_1	327	333	PF00454	0.749
MOD_PIKK_1	344	350	PF00454	0.593
MOD_PIKK_1	58	64	PF00454	0.698
MOD_PKA_2	151	157	PF00069	0.532
MOD_PKB_1	44	52	PF00069	0.611
MOD_Plk_1	108	114	PF00069	0.482
MOD_Plk_1	167	173	PF00069	0.417
MOD_Plk_1	215	221	PF00069	0.607
MOD_Plk_1	36	42	PF00069	0.684
MOD_Plk_1	5	11	PF00069	0.711
MOD_Plk_1	51	57	PF00069	0.527
MOD_Plk_1	91	97	PF00069	0.411
MOD_Plk_2-3	79	85	PF00069	0.689
MOD_Plk_4	108	114	PF00069	0.451
MOD_Plk_4	167	173	PF00069	0.533
MOD_Plk_4	320	326	PF00069	0.680
MOD_Plk_4	366	372	PF00069	0.742
MOD_Plk_4	97	103	PF00069	0.539
MOD_ProDKin_1	203	209	PF00069	0.714
MOD_ProDKin_1	224	230	PF00069	0.690
MOD_ProDKin_1	231	237	PF00069	0.631
MOD_ProDKin_1	25	31	PF00069	0.759
MOD_ProDKin_1	295	301	PF00069	0.589
MOD_ProDKin_1	317	323	PF00069	0.608
MOD_ProDKin_1	336	342	PF00069	0.523
MOD_ProDKin_1	397	403	PF00069	0.673
MOD_ProDKin_1	71	77	PF00069	0.772
TRG_DiLeu_BaLyEn_6	225	230	PF01217	0.669
TRG_DiLeu_BaLyEn_6	408	413	PF01217	0.640
TRG_ER_diArg_1	41	44	PF00400	0.625

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I162	Leptomonas seymouri	44%	73%
A0A3Q8IR74	Leishmania donovani	99%	100%
E9ADT9	Leishmania major	89%	100%
E9AIT6	Leishmania braziliensis	70%	100%
E9ALZ1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%