Secreted protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Secreted protein

Gene product:

Protein of unknown function (DUF2946), putative

Species:

Leishmania infantum

UniProt:

E9AHI2_LEIIN

TriTrypDb:

Length:

181

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AHI2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHI2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	119	123	PF00656	0.539
CLV_NRD_NRD_1	151	153	PF00675	0.549
CLV_NRD_NRD_1	34	36	PF00675	0.548
CLV_PCSK_KEX2_1	150	152	PF00082	0.561
CLV_PCSK_KEX2_1	34	36	PF00082	0.612
CLV_PCSK_PC1ET2_1	150	152	PF00082	0.561
CLV_PCSK_SKI1_1	147	151	PF00082	0.548
CLV_PCSK_SKI1_1	169	173	PF00082	0.583
DOC_MAPK_gen_1	147	156	PF00069	0.554
DOC_MAPK_gen_1	7	15	PF00069	0.670
DOC_USP7_MATH_1	48	52	PF00917	0.697
DOC_WW_Pin1_4	34	39	PF00397	0.620
DOC_WW_Pin1_4	46	51	PF00397	0.508
DOC_WW_Pin1_4	84	89	PF00397	0.826
LIG_14-3-3_CanoR_1	34	38	PF00244	0.596
LIG_14-3-3_CanoR_1	57	61	PF00244	0.712
LIG_DCNL_PONY_1	1	4	PF03556	0.757
LIG_FHA_1	119	125	PF00498	0.536
LIG_FHA_1	34	40	PF00498	0.644
LIG_FHA_2	117	123	PF00498	0.544
LIG_FHA_2	85	91	PF00498	0.695
LIG_LIR_Nem_3	138	144	PF02991	0.534
LIG_PDZ_Class_3	176	181	PF00595	0.564
LIG_SH2_STAT5	114	117	PF00017	0.743
LIG_SH2_STAT5	141	144	PF00017	0.540
LIG_SH3_1	91	97	PF00018	0.779
LIG_SH3_3	69	75	PF00018	0.793
LIG_SH3_3	91	97	PF00018	0.686
LIG_SUMO_SIM_par_1	11	17	PF11976	0.656
MOD_CDK_SPxxK_3	46	53	PF00069	0.693
MOD_CDK_SPxxK_3	84	91	PF00069	0.777
MOD_CK1_1	24	30	PF00069	0.677
MOD_CK1_1	46	52	PF00069	0.690
MOD_CK1_1	56	62	PF00069	0.724
MOD_CK1_1	84	90	PF00069	0.723
MOD_GSK3_1	110	117	PF00069	0.788
MOD_GSK3_1	17	24	PF00069	0.569
MOD_GSK3_1	33	40	PF00069	0.462
MOD_GSK3_1	49	56	PF00069	0.559
MOD_GSK3_1	80	87	PF00069	0.726
MOD_NEK2_1	100	105	PF00069	0.513
MOD_NEK2_1	21	26	PF00069	0.656
MOD_NEK2_1	55	60	PF00069	0.710
MOD_NEK2_1	82	87	PF00069	0.788
MOD_OFUCOSY	26	31	PF10250	0.672
MOD_PIKK_1	116	122	PF00454	0.686
MOD_PKA_2	33	39	PF00069	0.552
MOD_PKA_2	56	62	PF00069	0.710
MOD_PKA_2	8	14	PF00069	0.664
MOD_Plk_4	17	23	PF00069	0.522
MOD_Plk_4	8	14	PF00069	0.664
MOD_ProDKin_1	34	40	PF00069	0.620
MOD_ProDKin_1	46	52	PF00069	0.511
MOD_ProDKin_1	84	90	PF00069	0.821
TRG_DiLeu_BaLyEn_6	104	109	PF01217	0.747
TRG_NLS_MonoExtN_4	147	154	PF00514	0.549

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IBC6	Leishmania donovani	99%	79%