Uncharacterized protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AHH8_LEIIN

TriTrypDb:

LINF_280013600

Length:

252

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AHH8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHH8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_FUR_1	146	150	PF00082	0.478
CLV_PCSK_KEX2_1	148	150	PF00082	0.709
CLV_PCSK_KEX2_1	206	208	PF00082	0.666
CLV_PCSK_PC1ET2_1	148	150	PF00082	0.584
CLV_PCSK_PC1ET2_1	206	208	PF00082	0.666
CLV_PCSK_SKI1_1	79	83	PF00082	0.547
DEG_Nend_Nbox_1	1	3	PF02207	0.662
DOC_CYCLIN_yClb5_NLxxxL_5	219	228	PF00134	0.593
DOC_MAPK_gen_1	17	25	PF00069	0.582
DOC_MAPK_RevD_3	133	149	PF00069	0.494
DOC_MIT_MIM_1	201	211	PF04212	0.531
DOC_USP7_MATH_1	155	159	PF00917	0.688
DOC_USP7_MATH_1	175	179	PF00917	0.578
DOC_USP7_MATH_1	46	50	PF00917	0.596
DOC_USP7_MATH_1	75	79	PF00917	0.618
DOC_WW_Pin1_4	119	124	PF00397	0.667
DOC_WW_Pin1_4	44	49	PF00397	0.513
LIG_14-3-3_CanoR_1	11	16	PF00244	0.639
LIG_14-3-3_CanoR_1	244	252	PF00244	0.637
LIG_BRCT_BRCA1_1	238	242	PF00533	0.608
LIG_CtBP_PxDLS_1	142	146	PF00389	0.511
LIG_FHA_1	235	241	PF00498	0.603
LIG_FHA_1	29	35	PF00498	0.577
LIG_FHA_2	244	250	PF00498	0.632
LIG_FHA_2	90	96	PF00498	0.638
LIG_LIR_Gen_1	169	179	PF02991	0.709
LIG_LIR_Nem_3	169	174	PF02991	0.684
LIG_PDZ_Class_1	247	252	PF00595	0.539
LIG_SH2_CRK	171	175	PF00017	0.573
LIG_SH2_STAT5	110	113	PF00017	0.572
LIG_SH2_STAT5	151	154	PF00017	0.552
LIG_SH3_3	149	155	PF00018	0.555
LIG_SUMO_SIM_anti_2	215	220	PF11976	0.581
LIG_UBA3_1	221	226	PF00899	0.604
MOD_CK1_1	128	134	PF00069	0.645
MOD_CK1_1	89	95	PF00069	0.580
MOD_CK2_1	128	134	PF00069	0.664
MOD_CK2_1	243	249	PF00069	0.635
MOD_CK2_1	90	96	PF00069	0.547
MOD_GlcNHglycan	201	204	PF01048	0.527
MOD_GlcNHglycan	234	237	PF01048	0.668
MOD_GlcNHglycan	25	28	PF01048	0.603
MOD_GlcNHglycan	48	51	PF01048	0.618
MOD_GlcNHglycan	83	86	PF01048	0.581
MOD_GlcNHglycan	88	91	PF01048	0.537
MOD_GSK3_1	155	162	PF00069	0.591
MOD_GSK3_1	232	239	PF00069	0.667
MOD_GSK3_1	243	250	PF00069	0.560
MOD_GSK3_1	40	47	PF00069	0.611
MOD_GSK3_1	86	93	PF00069	0.562
MOD_LATS_1	9	15	PF00433	0.639
MOD_N-GLC_1	128	133	PF02516	0.601
MOD_N-GLC_2	245	247	PF02516	0.634
MOD_NEK2_1	209	214	PF00069	0.583
MOD_NEK2_1	224	229	PF00069	0.478
MOD_NEK2_1	40	45	PF00069	0.606
MOD_NEK2_1	99	104	PF00069	0.547
MOD_PIKK_1	62	68	PF00454	0.614
MOD_PIKK_1	90	96	PF00454	0.500
MOD_PKA_2	243	249	PF00069	0.641
MOD_Plk_1	175	181	PF00069	0.613
MOD_Plk_4	11	17	PF00069	0.645
MOD_Plk_4	166	172	PF00069	0.685
MOD_ProDKin_1	119	125	PF00069	0.663
MOD_ProDKin_1	44	50	PF00069	0.514
MOD_SUMO_rev_2	128	138	PF00179	0.573
TRG_DiLeu_BaEn_1	217	222	PF01217	0.591
TRG_ENDOCYTIC_2	171	174	PF00928	0.560

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IGN7	Leishmania donovani	98%	100%
A4HGC5	Leishmania braziliensis	73%	100%
E9ADJ9	Leishmania major	90%	100%
E9AZP6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%