Serine/threonine-protein kinase ATR

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AHH4_LEIIN

TriTrypDb:

LINF_280008500

Length:

258

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AHH4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHH4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	119	123	PF00656	0.474
CLV_C14_Caspase3-7	161	165	PF00656	0.308
CLV_NRD_NRD_1	92	94	PF00675	0.491
CLV_PCSK_SKI1_1	167	171	PF00082	0.287
CLV_PCSK_SKI1_1	62	66	PF00082	0.377
CLV_Separin_Metazoa	59	63	PF03568	0.380
DOC_CKS1_1	12	17	PF01111	0.371
DOC_CYCLIN_RxL_1	242	253	PF00134	0.305
DOC_MAPK_DCC_7	79	89	PF00069	0.476
DOC_MAPK_gen_1	171	178	PF00069	0.304
DOC_MAPK_gen_1	234	243	PF00069	0.364
DOC_MAPK_MEF2A_6	171	178	PF00069	0.304
DOC_USP7_MATH_1	114	118	PF00917	0.469
DOC_USP7_MATH_1	228	232	PF00917	0.318
DOC_USP7_MATH_1	95	99	PF00917	0.474
DOC_USP7_MATH_2	46	52	PF00917	0.435
DOC_WW_Pin1_4	11	16	PF00397	0.376
DOC_WW_Pin1_4	87	92	PF00397	0.499
LIG_14-3-3_CanoR_1	234	244	PF00244	0.360
LIG_APCC_ABBAyCdc20_2	193	199	PF00400	0.334
LIG_BIR_III_2	82	86	PF00653	0.477
LIG_Clathr_ClatBox_1	249	253	PF01394	0.310
LIG_FHA_1	63	69	PF00498	0.377
LIG_GBD_Chelix_1	243	251	PF00786	0.299
LIG_LIR_Apic_2	10	15	PF02991	0.376
LIG_LIR_Gen_1	181	191	PF02991	0.303
LIG_LIR_Gen_1	208	217	PF02991	0.307
LIG_LIR_Nem_3	181	186	PF02991	0.323
LIG_LIR_Nem_3	208	213	PF02991	0.289
LIG_LIR_Nem_3	55	60	PF02991	0.386
LIG_NRBOX	165	171	PF00104	0.282
LIG_NRBOX	246	252	PF00104	0.298
LIG_SH2_NCK_1	12	16	PF00017	0.376
LIG_SH2_SRC	44	47	PF00017	0.460
LIG_SH2_STAT5	168	171	PF00017	0.284
LIG_SH2_STAT5	44	47	PF00017	0.460
LIG_SUMO_SIM_anti_2	116	123	PF11976	0.477
LIG_SUMO_SIM_anti_2	240	245	PF11976	0.328
LIG_TRAF2_2	152	157	PF00917	0.427
LIG_UBA3_1	162	171	PF00899	0.287
LIG_WW_3	213	217	PF00397	0.322
MOD_CDC14_SPxK_1	90	93	PF00782	0.495
MOD_CDK_SPxK_1	87	93	PF00069	0.498
MOD_CDK_SPxxK_3	87	94	PF00069	0.497
MOD_CK1_1	200	206	PF00069	0.283
MOD_GlcNHglycan	198	202	PF01048	0.323
MOD_GlcNHglycan	226	229	PF01048	0.310
MOD_GlcNHglycan	237	240	PF01048	0.376
MOD_GlcNHglycan	25	28	PF01048	0.351
MOD_GlcNHglycan	50	53	PF01048	0.406
MOD_GlcNHglycan	96	100	PF01048	0.478
MOD_GSK3_1	19	26	PF00069	0.357
MOD_GSK3_1	224	231	PF00069	0.310
MOD_GSK3_1	235	242	PF00069	0.370
MOD_GSK3_1	68	75	PF00069	0.397
MOD_N-GLC_1	181	186	PF02516	0.323
MOD_NEK2_1	162	167	PF00069	0.290
MOD_NEK2_1	219	224	PF00069	0.301
MOD_NEK2_1	232	237	PF00069	0.382
MOD_NEK2_2	205	210	PF00069	0.273
MOD_PIKK_1	150	156	PF00454	0.421
MOD_PKA_2	19	25	PF00069	0.356
MOD_Plk_1	239	245	PF00069	0.332
MOD_Plk_4	205	211	PF00069	0.281
MOD_Plk_4	239	245	PF00069	0.332
MOD_Plk_4	40	46	PF00069	0.445
MOD_ProDKin_1	11	17	PF00069	0.371
MOD_ProDKin_1	87	93	PF00069	0.498
TRG_DiLeu_BaEn_1	158	163	PF01217	0.333
TRG_DiLeu_BaEn_4	158	164	PF01217	0.334
TRG_NES_CRM1_1	240	253	PF08389	0.313