LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
E9AHH3_LEIIN
TriTrypDb:
LINF_280007500 *
Length:
280

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
Term Name Level Count
GO:0016020 membrane 2 7
GO:0110165 cellular anatomical entity 1 7

Expansion

Sequence features

E9AHH3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHH3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 132 134 PF00675 0.656
CLV_NRD_NRD_1 26 28 PF00675 0.612
CLV_NRD_NRD_1 260 262 PF00675 0.467
CLV_PCSK_KEX2_1 132 134 PF00082 0.656
CLV_PCSK_KEX2_1 26 28 PF00082 0.612
DEG_APCC_DBOX_1 6 14 PF00400 0.359
DEG_SCF_FBW7_1 235 242 PF00400 0.731
DEG_SPOP_SBC_1 127 131 PF00917 0.479
DEG_SPOP_SBC_1 143 147 PF00917 0.458
DEG_SPOP_SBC_1 239 243 PF00917 0.656
DOC_USP7_MATH_1 127 131 PF00917 0.595
DOC_USP7_MATH_1 239 243 PF00917 0.659
DOC_USP7_MATH_1 272 276 PF00917 0.790
DOC_USP7_MATH_1 28 32 PF00917 0.430
DOC_USP7_MATH_1 64 68 PF00917 0.485
DOC_USP7_UBL2_3 69 73 PF12436 0.437
DOC_WW_Pin1_4 13 18 PF00397 0.393
DOC_WW_Pin1_4 235 240 PF00397 0.750
DOC_WW_Pin1_4 274 279 PF00397 0.701
DOC_WW_Pin1_4 37 42 PF00397 0.394
DOC_WW_Pin1_4 62 67 PF00397 0.551
LIG_14-3-3_CanoR_1 107 115 PF00244 0.420
LIG_14-3-3_CanoR_1 144 151 PF00244 0.512
LIG_14-3-3_CanoR_1 37 41 PF00244 0.399
LIG_14-3-3_CanoR_1 57 63 PF00244 0.393
LIG_APCC_ABBA_1 3 8 PF00400 0.357
LIG_BIR_II_1 1 5 PF00653 0.361
LIG_FHA_1 145 151 PF00498 0.479
LIG_FHA_1 157 163 PF00498 0.548
LIG_FHA_1 181 187 PF00498 0.356
LIG_FHA_1 225 231 PF00498 0.687
LIG_GBD_Chelix_1 171 179 PF00786 0.545
LIG_LIR_Gen_1 2 10 PF02991 0.356
LIG_LIR_Nem_3 188 194 PF02991 0.381
LIG_LIR_Nem_3 2 6 PF02991 0.359
LIG_MYND_1 66 70 PF01753 0.426
LIG_NRBOX 170 176 PF00104 0.278
LIG_Pex14_1 177 181 PF04695 0.343
LIG_PTAP_UEV_1 29 34 PF05743 0.421
LIG_PTB_Apo_2 149 156 PF02174 0.424
LIG_SH2_GRB2like 78 81 PF00017 0.427
LIG_SH2_STAT5 194 197 PF00017 0.618
LIG_SH2_STAT5 44 47 PF00017 0.356
LIG_SH3_1 27 33 PF00018 0.416
LIG_SH3_3 22 28 PF00018 0.416
LIG_SH3_3 60 66 PF00018 0.454
LIG_SH3_4 69 76 PF00018 0.422
LIG_SUMO_SIM_anti_2 167 173 PF11976 0.371
LIG_SUMO_SIM_par_1 182 188 PF11976 0.410
LIG_SUMO_SIM_par_1 47 53 PF11976 0.340
LIG_WW_1 41 44 PF00397 0.366
LIG_WW_3 23 27 PF00397 0.412
MOD_CDK_SPxxK_3 62 69 PF00069 0.474
MOD_CK1_1 117 123 PF00069 0.482
MOD_CK1_1 131 137 PF00069 0.429
MOD_CK1_1 139 145 PF00069 0.515
MOD_CK1_1 167 173 PF00069 0.380
MOD_CK1_1 202 208 PF00069 0.693
MOD_CK1_1 224 230 PF00069 0.697
MOD_CK1_1 240 246 PF00069 0.552
MOD_CK1_1 260 266 PF00069 0.748
MOD_CK1_1 79 85 PF00069 0.429
MOD_CK2_1 131 137 PF00069 0.408
MOD_GlcNHglycan 109 112 PF01048 0.630
MOD_GlcNHglycan 119 122 PF01048 0.690
MOD_GlcNHglycan 162 165 PF01048 0.642
MOD_GlcNHglycan 201 204 PF01048 0.460
MOD_GlcNHglycan 235 238 PF01048 0.500
MOD_GlcNHglycan 30 33 PF01048 0.621
MOD_GlcNHglycan 34 37 PF01048 0.628
MOD_GSK3_1 103 110 PF00069 0.428
MOD_GSK3_1 127 134 PF00069 0.457
MOD_GSK3_1 138 145 PF00069 0.538
MOD_GSK3_1 156 163 PF00069 0.449
MOD_GSK3_1 180 187 PF00069 0.335
MOD_GSK3_1 195 202 PF00069 0.666
MOD_GSK3_1 233 240 PF00069 0.785
MOD_GSK3_1 270 277 PF00069 0.696
MOD_GSK3_1 28 35 PF00069 0.384
MOD_GSK3_1 58 65 PF00069 0.502
MOD_GSK3_1 76 83 PF00069 0.416
MOD_GSK3_1 9 16 PF00069 0.370
MOD_N-GLC_1 102 107 PF02516 0.623
MOD_N-GLC_1 117 122 PF02516 0.599
MOD_N-GLC_1 153 158 PF02516 0.655
MOD_N-GLC_1 167 172 PF02516 0.520
MOD_N-GLC_1 79 84 PF02516 0.635
MOD_N-GLC_1 90 95 PF02516 0.635
MOD_N-GLC_2 193 195 PF02516 0.477
MOD_NEK2_1 136 141 PF00069 0.521
MOD_NEK2_1 155 160 PF00069 0.433
MOD_NEK2_1 180 185 PF00069 0.325
MOD_NEK2_1 223 228 PF00069 0.737
MOD_NEK2_1 245 250 PF00069 0.654
MOD_NEK2_1 257 262 PF00069 0.661
MOD_NEK2_1 50 55 PF00069 0.346
MOD_PIKK_1 224 230 PF00454 0.674
MOD_PKA_2 131 137 PF00069 0.464
MOD_PKA_2 143 149 PF00069 0.499
MOD_PKA_2 260 266 PF00069 0.767
MOD_PKA_2 36 42 PF00069 0.484
MOD_PKB_1 55 63 PF00069 0.425
MOD_Plk_1 136 142 PF00069 0.479
MOD_Plk_1 167 173 PF00069 0.377
MOD_Plk_1 90 96 PF00069 0.431
MOD_Plk_4 167 173 PF00069 0.397
MOD_ProDKin_1 13 19 PF00069 0.396
MOD_ProDKin_1 235 241 PF00069 0.747
MOD_ProDKin_1 274 280 PF00069 0.703
MOD_ProDKin_1 37 43 PF00069 0.388
MOD_ProDKin_1 62 68 PF00069 0.552
TRG_DiLeu_BaLyEn_6 241 246 PF01217 0.666
TRG_DiLeu_BaLyEn_6 43 48 PF01217 0.353
TRG_ENDOCYTIC_2 44 47 PF00928 0.356
TRG_ER_diArg_1 25 27 PF00400 0.412
TRG_ER_diArg_1 54 57 PF00400 0.407
TRG_ER_FFAT_2 134 146 PF00635 0.511
TRG_Pf-PMV_PEXEL_1 133 137 PF00026 0.659

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P4Z6 Leptomonas seymouri 43% 100%
A0A3Q8IQC4 Leishmania donovani 99% 100%
A4HG88 Leishmania braziliensis 53% 98%
E9AZK9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 82% 100%
Q4Q8M2 Leishmania major 81% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS