LeishMANIAdb
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Nsp1_C domain-containing protein

Quick info Annotations Function or PPIs Localization Phosphorylation Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Nsp1_C domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
E9AHH2_LEIIN
TriTrypDb:
LINF_280039700 *
Length:
754

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized (Fragment)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 2
NetGPI no yes: 0, no: 2
Could not find GO cellular_component term for this entry.

Phosphorylation

Amastigote: 598
Promastigote/Amastigote: 599

Expansion

Sequence features

E9AHH2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHH2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 112 116 PF00656 0.393
CLV_C14_Caspase3-7 132 136 PF00656 0.383
CLV_C14_Caspase3-7 152 156 PF00656 0.382
CLV_C14_Caspase3-7 172 176 PF00656 0.390
CLV_C14_Caspase3-7 192 196 PF00656 0.373
CLV_C14_Caspase3-7 212 216 PF00656 0.375
CLV_C14_Caspase3-7 232 236 PF00656 0.384
CLV_C14_Caspase3-7 252 256 PF00656 0.376
CLV_C14_Caspase3-7 272 276 PF00656 0.377
CLV_C14_Caspase3-7 292 296 PF00656 0.376
CLV_C14_Caspase3-7 312 316 PF00656 0.380
CLV_C14_Caspase3-7 332 336 PF00656 0.377
CLV_C14_Caspase3-7 352 356 PF00656 0.379
CLV_C14_Caspase3-7 372 376 PF00656 0.373
CLV_C14_Caspase3-7 392 396 PF00656 0.385
CLV_C14_Caspase3-7 412 416 PF00656 0.390
CLV_C14_Caspase3-7 432 436 PF00656 0.380
CLV_C14_Caspase3-7 452 456 PF00656 0.388
CLV_C14_Caspase3-7 472 476 PF00656 0.389
CLV_C14_Caspase3-7 492 496 PF00656 0.399
CLV_C14_Caspase3-7 512 516 PF00656 0.437
CLV_C14_Caspase3-7 646 650 PF00656 0.464
CLV_C14_Caspase3-7 72 76 PF00656 0.439
CLV_C14_Caspase3-7 92 96 PF00656 0.403
CLV_NRD_NRD_1 657 659 PF00675 0.604
CLV_PCSK_KEX2_1 657 659 PF00082 0.604
CLV_PCSK_SKI1_1 105 109 PF00082 0.370
CLV_PCSK_SKI1_1 125 129 PF00082 0.376
CLV_PCSK_SKI1_1 145 149 PF00082 0.366
CLV_PCSK_SKI1_1 165 169 PF00082 0.366
CLV_PCSK_SKI1_1 185 189 PF00082 0.376
CLV_PCSK_SKI1_1 205 209 PF00082 0.365
CLV_PCSK_SKI1_1 225 229 PF00082 0.366
CLV_PCSK_SKI1_1 245 249 PF00082 0.367
CLV_PCSK_SKI1_1 265 269 PF00082 0.374
CLV_PCSK_SKI1_1 285 289 PF00082 0.360
CLV_PCSK_SKI1_1 305 309 PF00082 0.363
CLV_PCSK_SKI1_1 325 329 PF00082 0.375
CLV_PCSK_SKI1_1 345 349 PF00082 0.366
CLV_PCSK_SKI1_1 365 369 PF00082 0.362
CLV_PCSK_SKI1_1 385 389 PF00082 0.365
CLV_PCSK_SKI1_1 405 409 PF00082 0.378
CLV_PCSK_SKI1_1 425 429 PF00082 0.365
CLV_PCSK_SKI1_1 445 449 PF00082 0.381
CLV_PCSK_SKI1_1 465 469 PF00082 0.370
CLV_PCSK_SKI1_1 485 489 PF00082 0.371
CLV_PCSK_SKI1_1 505 509 PF00082 0.387
CLV_PCSK_SKI1_1 525 529 PF00082 0.437
CLV_PCSK_SKI1_1 579 583 PF00082 0.523
CLV_PCSK_SKI1_1 616 620 PF00082 0.334
CLV_PCSK_SKI1_1 65 69 PF00082 0.416
CLV_PCSK_SKI1_1 695 699 PF00082 0.431
CLV_PCSK_SKI1_1 733 737 PF00082 0.461
CLV_PCSK_SKI1_1 85 89 PF00082 0.369
DEG_SCF_FBW7_1 7 13 PF00400 0.542
DEG_SCF_TRCP1_1 646 651 PF00400 0.470
DEG_SPOP_SBC_1 40 44 PF00917 0.494
DOC_CKS1_1 682 687 PF01111 0.497
DOC_CKS1_1 7 12 PF01111 0.542
DOC_PP4_FxxP_1 682 685 PF00568 0.503
DOC_USP7_MATH_1 10 14 PF00917 0.544
DOC_USP7_MATH_1 103 107 PF00917 0.364
DOC_USP7_MATH_1 121 125 PF00917 0.401
DOC_USP7_MATH_1 143 147 PF00917 0.365
DOC_USP7_MATH_1 163 167 PF00917 0.367
DOC_USP7_MATH_1 181 185 PF00917 0.397
DOC_USP7_MATH_1 203 207 PF00917 0.363
DOC_USP7_MATH_1 223 227 PF00917 0.357
DOC_USP7_MATH_1 241 245 PF00917 0.373
DOC_USP7_MATH_1 261 265 PF00917 0.397
DOC_USP7_MATH_1 283 287 PF00917 0.360
DOC_USP7_MATH_1 303 307 PF00917 0.358
DOC_USP7_MATH_1 31 35 PF00917 0.504
DOC_USP7_MATH_1 321 325 PF00917 0.402
DOC_USP7_MATH_1 343 347 PF00917 0.373
DOC_USP7_MATH_1 363 367 PF00917 0.363
DOC_USP7_MATH_1 383 387 PF00917 0.357
DOC_USP7_MATH_1 40 44 PF00917 0.490
DOC_USP7_MATH_1 401 405 PF00917 0.395
DOC_USP7_MATH_1 423 427 PF00917 0.365
DOC_USP7_MATH_1 441 445 PF00917 0.392
DOC_USP7_MATH_1 463 467 PF00917 0.369
DOC_USP7_MATH_1 483 487 PF00917 0.361
DOC_USP7_MATH_1 501 505 PF00917 0.381
DOC_USP7_MATH_1 523 527 PF00917 0.429
DOC_USP7_MATH_1 540 544 PF00917 0.497
DOC_USP7_MATH_1 558 562 PF00917 0.479
DOC_USP7_MATH_1 596 600 PF00917 0.471
DOC_USP7_MATH_1 63 67 PF00917 0.435
DOC_USP7_MATH_1 706 710 PF00917 0.501
DOC_USP7_MATH_1 83 87 PF00917 0.371
DOC_WW_Pin1_4 27 32 PF00397 0.506
DOC_WW_Pin1_4 48 53 PF00397 0.511
DOC_WW_Pin1_4 574 579 PF00397 0.601
DOC_WW_Pin1_4 6 11 PF00397 0.541
DOC_WW_Pin1_4 681 686 PF00397 0.495
LIG_14-3-3_CanoR_1 678 682 PF00244 0.501
LIG_BIR_II_1 1 5 PF00653 0.526
LIG_BRCT_BRCA1_1 678 682 PF00533 0.496
LIG_FHA_1 638 644 PF00498 0.312
LIG_FHA_1 682 688 PF00498 0.492
LIG_FHA_1 711 717 PF00498 0.537
LIG_LIR_Apic_2 533 537 PF02991 0.494
LIG_LIR_Apic_2 679 685 PF02991 0.491
LIG_LIR_Apic_2 693 699 PF02991 0.435
LIG_LIR_Nem_3 106 111 PF02991 0.363
LIG_LIR_Nem_3 126 131 PF02991 0.368
LIG_LIR_Nem_3 146 151 PF02991 0.359
LIG_LIR_Nem_3 166 171 PF02991 0.359
LIG_LIR_Nem_3 186 191 PF02991 0.366
LIG_LIR_Nem_3 206 211 PF02991 0.357
LIG_LIR_Nem_3 226 231 PF02991 0.357
LIG_LIR_Nem_3 246 251 PF02991 0.358
LIG_LIR_Nem_3 266 271 PF02991 0.366
LIG_LIR_Nem_3 286 291 PF02991 0.349
LIG_LIR_Nem_3 306 311 PF02991 0.355
LIG_LIR_Nem_3 326 331 PF02991 0.364
LIG_LIR_Nem_3 346 351 PF02991 0.357
LIG_LIR_Nem_3 366 371 PF02991 0.350
LIG_LIR_Nem_3 386 391 PF02991 0.358
LIG_LIR_Nem_3 406 411 PF02991 0.371
LIG_LIR_Nem_3 426 431 PF02991 0.355
LIG_LIR_Nem_3 446 451 PF02991 0.373
LIG_LIR_Nem_3 466 471 PF02991 0.362
LIG_LIR_Nem_3 486 491 PF02991 0.363
LIG_LIR_Nem_3 506 511 PF02991 0.388
LIG_LIR_Nem_3 526 531 PF02991 0.717
LIG_LIR_Nem_3 604 610 PF02991 0.295
LIG_LIR_Nem_3 66 71 PF02991 0.408
LIG_LIR_Nem_3 86 91 PF02991 0.365
LIG_Pex14_2 104 108 PF04695 0.365
LIG_Pex14_2 144 148 PF04695 0.369
LIG_Pex14_2 164 168 PF04695 0.370
LIG_Pex14_2 204 208 PF04695 0.368
LIG_Pex14_2 224 228 PF04695 0.360
LIG_Pex14_2 284 288 PF04695 0.363
LIG_Pex14_2 304 308 PF04695 0.359
LIG_Pex14_2 344 348 PF04695 0.369
LIG_Pex14_2 364 368 PF04695 0.365
LIG_Pex14_2 384 388 PF04695 0.360
LIG_Pex14_2 424 428 PF04695 0.368
LIG_Pex14_2 464 468 PF04695 0.373
LIG_Pex14_2 484 488 PF04695 0.366
LIG_Pex14_2 524 528 PF04695 0.435
LIG_Pex14_2 84 88 PF04695 0.385
LIG_SH2_CRK 696 700 PF00017 0.422
LIG_SH3_3 108 114 PF00018 0.376
LIG_SH3_3 12 18 PF00018 0.538
LIG_SH3_3 128 134 PF00018 0.376
LIG_SH3_3 148 154 PF00018 0.370
LIG_SH3_3 168 174 PF00018 0.369
LIG_SH3_3 188 194 PF00018 0.370
LIG_SH3_3 208 214 PF00018 0.366
LIG_SH3_3 228 234 PF00018 0.366
LIG_SH3_3 248 254 PF00018 0.366
LIG_SH3_3 25 31 PF00018 0.509
LIG_SH3_3 268 274 PF00018 0.373
LIG_SH3_3 288 294 PF00018 0.359
LIG_SH3_3 308 314 PF00018 0.364
LIG_SH3_3 328 334 PF00018 0.371
LIG_SH3_3 348 354 PF00018 0.365
LIG_SH3_3 368 374 PF00018 0.359
LIG_SH3_3 388 394 PF00018 0.367
LIG_SH3_3 4 10 PF00018 0.534
LIG_SH3_3 408 414 PF00018 0.380
LIG_SH3_3 428 434 PF00018 0.362
LIG_SH3_3 448 454 PF00018 0.378
LIG_SH3_3 46 52 PF00018 0.511
LIG_SH3_3 468 474 PF00018 0.371
LIG_SH3_3 488 494 PF00018 0.373
LIG_SH3_3 508 514 PF00018 0.408
LIG_SH3_3 534 540 PF00018 0.491
LIG_SH3_3 68 74 PF00018 0.419
LIG_SH3_3 682 688 PF00018 0.490
LIG_SH3_3 88 94 PF00018 0.381
LIG_SUMO_SIM_anti_2 711 719 PF11976 0.475
LIG_SUMO_SIM_par_1 711 719 PF11976 0.475
MOD_CDK_SPK_2 574 579 PF00069 0.519
MOD_CK1_1 39 45 PF00069 0.494
MOD_CK1_1 548 554 PF00069 0.484
MOD_CK1_1 561 567 PF00069 0.484
MOD_CK1_1 571 577 PF00069 0.520
MOD_CK1_1 628 634 PF00069 0.320
MOD_CK1_1 745 751 PF00069 0.355
MOD_CK2_1 561 567 PF00069 0.582
MOD_CK2_1 686 692 PF00069 0.464
MOD_Cter_Amidation 636 639 PF01082 0.370
MOD_GlcNHglycan 105 108 PF01048 0.368
MOD_GlcNHglycan 111 114 PF01048 0.371
MOD_GlcNHglycan 125 128 PF01048 0.373
MOD_GlcNHglycan 131 134 PF01048 0.369
MOD_GlcNHglycan 145 148 PF01048 0.365
MOD_GlcNHglycan 151 154 PF01048 0.365
MOD_GlcNHglycan 165 168 PF01048 0.367
MOD_GlcNHglycan 171 174 PF01048 0.366
MOD_GlcNHglycan 185 188 PF01048 0.375
MOD_GlcNHglycan 191 194 PF01048 0.361
MOD_GlcNHglycan 205 208 PF01048 0.364
MOD_GlcNHglycan 211 214 PF01048 0.358
MOD_GlcNHglycan 225 228 PF01048 0.365
MOD_GlcNHglycan 231 234 PF01048 0.359
MOD_GlcNHglycan 245 248 PF01048 0.365
MOD_GlcNHglycan 251 254 PF01048 0.359
MOD_GlcNHglycan 265 268 PF01048 0.372
MOD_GlcNHglycan 271 274 PF01048 0.363
MOD_GlcNHglycan 285 288 PF01048 0.359
MOD_GlcNHglycan 291 294 PF01048 0.358
MOD_GlcNHglycan 305 308 PF01048 0.364
MOD_GlcNHglycan 31 34 PF01048 0.506
MOD_GlcNHglycan 311 314 PF01048 0.359
MOD_GlcNHglycan 325 328 PF01048 0.374
MOD_GlcNHglycan 331 334 PF01048 0.363
MOD_GlcNHglycan 345 348 PF01048 0.366
MOD_GlcNHglycan 351 354 PF01048 0.359
MOD_GlcNHglycan 365 368 PF01048 0.361
MOD_GlcNHglycan 371 374 PF01048 0.357
MOD_GlcNHglycan 38 41 PF01048 0.495
MOD_GlcNHglycan 385 388 PF01048 0.365
MOD_GlcNHglycan 391 394 PF01048 0.362
MOD_GlcNHglycan 405 408 PF01048 0.377
MOD_GlcNHglycan 411 414 PF01048 0.374
MOD_GlcNHglycan 425 428 PF01048 0.365
MOD_GlcNHglycan 431 434 PF01048 0.358
MOD_GlcNHglycan 445 448 PF01048 0.381
MOD_GlcNHglycan 451 454 PF01048 0.369
MOD_GlcNHglycan 465 468 PF01048 0.370
MOD_GlcNHglycan 471 474 PF01048 0.365
MOD_GlcNHglycan 485 488 PF01048 0.372
MOD_GlcNHglycan 491 494 PF01048 0.370
MOD_GlcNHglycan 505 508 PF01048 0.386
MOD_GlcNHglycan 511 514 PF01048 0.414
MOD_GlcNHglycan 525 528 PF01048 0.436
MOD_GlcNHglycan 533 537 PF01048 0.490
MOD_GlcNHglycan 542 545 PF01048 0.496
MOD_GlcNHglycan 554 559 PF01048 0.478
MOD_GlcNHglycan 570 573 PF01048 0.519
MOD_GlcNHglycan 645 649 PF01048 0.437
MOD_GlcNHglycan 65 68 PF01048 0.416
MOD_GlcNHglycan 71 74 PF01048 0.406
MOD_GlcNHglycan 718 721 PF01048 0.425
MOD_GlcNHglycan 85 88 PF01048 0.366
MOD_GlcNHglycan 91 94 PF01048 0.378
MOD_GSK3_1 103 110 PF00069 0.371
MOD_GSK3_1 203 210 PF00069 0.371
MOD_GSK3_1 263 270 PF00069 0.383
MOD_GSK3_1 27 34 PF00069 0.506
MOD_GSK3_1 303 310 PF00069 0.371
MOD_GSK3_1 323 330 PF00069 0.375
MOD_GSK3_1 343 350 PF00069 0.363
MOD_GSK3_1 36 43 PF00069 0.497
MOD_GSK3_1 383 390 PF00069 0.372
MOD_GSK3_1 403 410 PF00069 0.377
MOD_GSK3_1 443 450 PF00069 0.387
MOD_GSK3_1 463 470 PF00069 0.367
MOD_GSK3_1 48 55 PF00069 0.499
MOD_GSK3_1 540 547 PF00069 0.508
MOD_GSK3_1 550 557 PF00069 0.477
MOD_GSK3_1 558 565 PF00069 0.481
MOD_GSK3_1 6 13 PF00069 0.541
MOD_GSK3_1 644 651 PF00069 0.447
MOD_GSK3_1 677 684 PF00069 0.491
MOD_GSK3_1 706 713 PF00069 0.692
MOD_GSK3_1 83 90 PF00069 0.385
MOD_N-GLC_1 562 567 PF02516 0.709
MOD_NEK2_1 36 41 PF00069 0.502
MOD_NEK2_1 595 600 PF00069 0.482
MOD_NEK2_1 677 682 PF00069 0.610
MOD_NEK2_2 31 36 PF00069 0.506
MOD_NEK2_2 625 630 PF00069 0.343
MOD_NEK2_2 742 747 PF00069 0.364
MOD_PIKK_1 10 16 PF00454 0.546
MOD_PIKK_1 42 48 PF00454 0.499
MOD_PKA_1 638 644 PF00069 0.312
MOD_PKA_1 657 663 PF00069 0.504
MOD_PKA_2 657 663 PF00069 0.504
MOD_PKA_2 677 683 PF00069 0.695
MOD_Plk_1 554 560 PF00069 0.485
MOD_Plk_1 596 602 PF00069 0.458
MOD_Plk_1 710 716 PF00069 0.722
MOD_Plk_4 31 37 PF00069 0.505
MOD_Plk_4 638 644 PF00069 0.361
MOD_Plk_4 648 654 PF00069 0.509
MOD_Plk_4 677 683 PF00069 0.496
MOD_Plk_4 711 717 PF00069 0.483
MOD_ProDKin_1 27 33 PF00069 0.505
MOD_ProDKin_1 48 54 PF00069 0.510
MOD_ProDKin_1 574 580 PF00069 0.601
MOD_ProDKin_1 6 12 PF00069 0.541
MOD_ProDKin_1 681 687 PF00069 0.494
TRG_DiLeu_BaEn_3 692 698 PF01217 0.443

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7X1Z0 Leishmania donovani 94% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS