Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RING-H2 zinc finger/Anaphase-promoting complex subunit 11 RING-H2 finger/Ring finger domain containing protein - putative

Species:

Leishmania infantum

UniProt:

E9AHF8_LEIIN

TriTrypDb:

LINF_270018400

Length:

415

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AHF8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHF8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	3	7	PF00656	0.737
CLV_NRD_NRD_1	159	161	PF00675	0.736
CLV_NRD_NRD_1	162	164	PF00675	0.720
CLV_NRD_NRD_1	24	26	PF00675	0.669
CLV_NRD_NRD_1	402	404	PF00675	0.803
CLV_NRD_NRD_1	97	99	PF00675	0.776
CLV_PCSK_FUR_1	160	164	PF00082	0.574
CLV_PCSK_FUR_1	95	99	PF00082	0.776
CLV_PCSK_KEX2_1	159	161	PF00082	0.666
CLV_PCSK_KEX2_1	162	164	PF00082	0.674
CLV_PCSK_KEX2_1	24	26	PF00082	0.673
CLV_PCSK_KEX2_1	288	290	PF00082	0.581
CLV_PCSK_KEX2_1	402	404	PF00082	0.811
CLV_PCSK_KEX2_1	97	99	PF00082	0.776
CLV_PCSK_PC1ET2_1	288	290	PF00082	0.592
CLV_PCSK_PC7_1	284	290	PF00082	0.593
CLV_PCSK_SKI1_1	125	129	PF00082	0.710
CLV_PCSK_SKI1_1	75	79	PF00082	0.667
DEG_APCC_DBOX_1	247	255	PF00400	0.513
DEG_Nend_Nbox_1	1	3	PF02207	0.798
DEG_SPOP_SBC_1	181	185	PF00917	0.720
DEG_SPOP_SBC_1	330	334	PF00917	0.719
DOC_MAPK_gen_1	159	167	PF00069	0.658
DOC_MAPK_gen_1	24	34	PF00069	0.636
DOC_MAPK_gen_1	97	106	PF00069	0.691
DOC_MAPK_MEF2A_6	25	34	PF00069	0.620
DOC_PP2B_LxvP_1	195	198	PF13499	0.651
DOC_PP2B_LxvP_1	389	392	PF13499	0.731
DOC_PP4_FxxP_1	237	240	PF00568	0.513
DOC_USP7_MATH_1	139	143	PF00917	0.690
DOC_USP7_MATH_1	161	165	PF00917	0.790
DOC_USP7_MATH_1	181	185	PF00917	0.579
DOC_USP7_MATH_1	198	202	PF00917	0.656
DOC_USP7_MATH_1	318	322	PF00917	0.596
DOC_USP7_MATH_1	330	334	PF00917	0.525
DOC_USP7_MATH_1	360	364	PF00917	0.662
DOC_USP7_MATH_1	394	398	PF00917	0.765
DOC_USP7_MATH_1	47	51	PF00917	0.587
DOC_USP7_MATH_1	63	67	PF00917	0.723
DOC_WW_Pin1_4	147	152	PF00397	0.648
DOC_WW_Pin1_4	182	187	PF00397	0.731
DOC_WW_Pin1_4	25	30	PF00397	0.757
DOC_WW_Pin1_4	326	331	PF00397	0.654
DOC_WW_Pin1_4	334	339	PF00397	0.766
DOC_WW_Pin1_4	367	372	PF00397	0.681
DOC_WW_Pin1_4	66	71	PF00397	0.618
DOC_WW_Pin1_4	7	12	PF00397	0.706
DOC_WW_Pin1_4	88	93	PF00397	0.714
LIG_14-3-3_CanoR_1	160	166	PF00244	0.686
LIG_14-3-3_CanoR_1	248	252	PF00244	0.411
LIG_14-3-3_CanoR_1	405	414	PF00244	0.628
LIG_14-3-3_CanoR_1	64	70	PF00244	0.738
LIG_14-3-3_CanoR_1	72	78	PF00244	0.669
LIG_14-3-3_CanoR_1	97	106	PF00244	0.691
LIG_CaM_IQ_9	349	364	PF13499	0.588
LIG_DLG_GKlike_1	163	171	PF00625	0.665
LIG_FHA_1	147	153	PF00498	0.727
LIG_FHA_1	166	172	PF00498	0.511
LIG_FHA_1	175	181	PF00498	0.638
LIG_FHA_1	21	27	PF00498	0.731
LIG_FHA_1	314	320	PF00498	0.565
LIG_FHA_1	339	345	PF00498	0.648
LIG_FHA_1	63	69	PF00498	0.667
LIG_FHA_2	77	83	PF00498	0.676
LIG_LIR_Nem_3	321	325	PF02991	0.612
LIG_MYND_1	189	193	PF01753	0.566
LIG_PTB_Apo_2	223	230	PF02174	0.513
LIG_SH2_GRB2like	222	225	PF00017	0.436
LIG_SH2_SRC	312	315	PF00017	0.530
LIG_SH2_STAP1	314	318	PF00017	0.558
LIG_SH2_STAT3	301	304	PF00017	0.550
LIG_SH2_STAT3	314	317	PF00017	0.398
LIG_SH2_STAT5	222	225	PF00017	0.436
LIG_SH2_STAT5	301	304	PF00017	0.467
LIG_SH3_3	133	139	PF00018	0.601
LIG_SH3_3	183	189	PF00018	0.665
LIG_SH3_3	190	196	PF00018	0.590
LIG_SH3_3	23	29	PF00018	0.603
LIG_SH3_3	373	379	PF00018	0.726
LIG_SH3_3	390	396	PF00018	0.802
LIG_TRAF2_1	176	179	PF00917	0.780
LIG_TRAF2_1	397	400	PF00917	0.732
LIG_TRAF2_1	79	82	PF00917	0.671
LIG_WRC_WIRS_1	319	324	PF05994	0.596
MOD_CAAXbox	412	415	PF01239	0.669
MOD_CDC14_SPxK_1	69	72	PF00782	0.678
MOD_CDK_SPxK_1	66	72	PF00069	0.617
MOD_CDK_SPxxK_3	147	154	PF00069	0.691
MOD_CDK_SPxxK_3	7	14	PF00069	0.574
MOD_CDK_SPxxK_3	88	95	PF00069	0.732
MOD_CK1_1	107	113	PF00069	0.718
MOD_CK1_1	15	21	PF00069	0.746
MOD_CK1_1	155	161	PF00069	0.626
MOD_CK1_1	166	172	PF00069	0.632
MOD_CK1_1	174	180	PF00069	0.524
MOD_CK1_1	184	190	PF00069	0.488
MOD_CK1_1	329	335	PF00069	0.705
MOD_CK1_1	387	393	PF00069	0.645
MOD_CK1_1	401	407	PF00069	0.619
MOD_CK1_1	55	61	PF00069	0.710
MOD_CK1_1	66	72	PF00069	0.797
MOD_CK1_1	7	13	PF00069	0.708
MOD_CK1_1	76	82	PF00069	0.629
MOD_CK2_1	197	203	PF00069	0.768
MOD_CK2_1	394	400	PF00069	0.689
MOD_CK2_1	76	82	PF00069	0.697
MOD_DYRK1A_RPxSP_1	25	29	PF00069	0.647
MOD_GlcNHglycan	132	135	PF01048	0.651
MOD_GlcNHglycan	141	144	PF01048	0.553
MOD_GlcNHglycan	203	207	PF01048	0.621
MOD_GlcNHglycan	326	329	PF01048	0.664
MOD_GlcNHglycan	362	365	PF01048	0.620
MOD_GlcNHglycan	43	46	PF01048	0.656
MOD_GlcNHglycan	58	61	PF01048	0.677
MOD_GlcNHglycan	6	10	PF01048	0.608
MOD_GlcNHglycan	65	68	PF01048	0.722
MOD_GSK3_1	1	8	PF00069	0.611
MOD_GSK3_1	102	109	PF00069	0.783
MOD_GSK3_1	161	168	PF00069	0.709
MOD_GSK3_1	170	177	PF00069	0.637
MOD_GSK3_1	180	187	PF00069	0.565
MOD_GSK3_1	198	205	PF00069	0.659
MOD_GSK3_1	324	331	PF00069	0.635
MOD_GSK3_1	334	341	PF00069	0.653
MOD_GSK3_1	394	401	PF00069	0.690
MOD_GSK3_1	48	55	PF00069	0.641
MOD_GSK3_1	62	69	PF00069	0.721
MOD_N-GLC_2	356	358	PF02516	0.720
MOD_NEK2_1	106	111	PF00069	0.722
MOD_NEK2_1	167	172	PF00069	0.741
MOD_NEK2_1	180	185	PF00069	0.751
MOD_NEK2_1	266	271	PF00069	0.676
MOD_NEK2_1	39	44	PF00069	0.580
MOD_NEK2_1	398	403	PF00069	0.636
MOD_NEK2_1	48	53	PF00069	0.598
MOD_NEK2_1	5	10	PF00069	0.569
MOD_NEK2_1	56	61	PF00069	0.800
MOD_NEK2_1	73	78	PF00069	0.695
MOD_NEK2_2	256	261	PF00069	0.565
MOD_PIKK_1	112	118	PF00454	0.717
MOD_PIKK_1	313	319	PF00454	0.560
MOD_PIKK_1	384	390	PF00454	0.740
MOD_PIKK_1	405	411	PF00454	0.609
MOD_PIKK_1	48	54	PF00454	0.693
MOD_PKA_1	97	103	PF00069	0.768
MOD_PKA_2	112	118	PF00069	0.715
MOD_PKA_2	161	167	PF00069	0.787
MOD_PKA_2	174	180	PF00069	0.562
MOD_PKA_2	247	253	PF00069	0.513
MOD_PKA_2	379	385	PF00069	0.739
MOD_PKA_2	401	407	PF00069	0.701
MOD_PKA_2	63	69	PF00069	0.723
MOD_PKA_2	97	103	PF00069	0.778
MOD_PKB_1	403	411	PF00069	0.614
MOD_PKB_1	95	103	PF00069	0.810
MOD_Plk_4	167	173	PF00069	0.702
MOD_Plk_4	73	79	PF00069	0.670
MOD_ProDKin_1	147	153	PF00069	0.648
MOD_ProDKin_1	182	188	PF00069	0.730
MOD_ProDKin_1	25	31	PF00069	0.748
MOD_ProDKin_1	326	332	PF00069	0.658
MOD_ProDKin_1	334	340	PF00069	0.765
MOD_ProDKin_1	367	373	PF00069	0.680
MOD_ProDKin_1	66	72	PF00069	0.617
MOD_ProDKin_1	7	13	PF00069	0.708
MOD_ProDKin_1	88	94	PF00069	0.712
TRG_ER_diArg_1	159	162	PF00400	0.648
TRG_ER_diArg_1	24	27	PF00400	0.674
TRG_ER_diArg_1	307	310	PF00400	0.491
TRG_ER_diArg_1	402	405	PF00400	0.811
TRG_ER_diArg_1	95	98	PF00400	0.773
TRG_Pf-PMV_PEXEL_1	261	265	PF00026	0.620

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZY3	Leptomonas seymouri	34%	88%
A0A3S7X0M5	Leishmania donovani	100%	100%
A4HFP6	Leishmania braziliensis	52%	100%
E9AD98	Leishmania major	86%	100%
E9AZ23	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	98%