LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
E9AHD4_LEIIN
TriTrypDb:
LINF_270012400
Length:
314

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AHD4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHD4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 211 213 PF00675 0.576
CLV_NRD_NRD_1 283 285 PF00675 0.512
CLV_NRD_NRD_1 30 32 PF00675 0.565
CLV_NRD_NRD_1 54 56 PF00675 0.548
CLV_PCSK_FUR_1 28 32 PF00082 0.641
CLV_PCSK_FUR_1 52 56 PF00082 0.582
CLV_PCSK_KEX2_1 108 110 PF00082 0.619
CLV_PCSK_KEX2_1 210 212 PF00082 0.580
CLV_PCSK_KEX2_1 283 285 PF00082 0.616
CLV_PCSK_KEX2_1 30 32 PF00082 0.560
CLV_PCSK_KEX2_1 54 56 PF00082 0.543
CLV_PCSK_PC1ET2_1 108 110 PF00082 0.619
CLV_PCSK_PC7_1 207 213 PF00082 0.565
CLV_PCSK_SKI1_1 161 165 PF00082 0.664
CLV_PCSK_SKI1_1 243 247 PF00082 0.567
CLV_PCSK_SKI1_1 37 41 PF00082 0.520
DEG_APCC_DBOX_1 289 297 PF00400 0.441
DEG_Nend_Nbox_1 1 3 PF02207 0.679
DEG_SPOP_SBC_1 155 159 PF00917 0.596
DEG_SPOP_SBC_1 4 8 PF00917 0.664
DOC_CYCLIN_RxL_1 161 172 PF00134 0.634
DOC_MAPK_DCC_7 161 169 PF00069 0.654
DOC_MAPK_gen_1 108 117 PF00069 0.577
DOC_MAPK_gen_1 52 59 PF00069 0.662
DOC_MAPK_MEF2A_6 161 170 PF00069 0.739
DOC_USP7_MATH_1 154 158 PF00917 0.709
DOC_USP7_MATH_1 231 235 PF00917 0.657
DOC_USP7_MATH_1 238 242 PF00917 0.552
DOC_USP7_MATH_1 4 8 PF00917 0.751
DOC_WW_Pin1_4 129 134 PF00397 0.738
DOC_WW_Pin1_4 143 148 PF00397 0.568
LIG_14-3-3_CanoR_1 112 118 PF00244 0.592
LIG_14-3-3_CanoR_1 232 236 PF00244 0.649
LIG_14-3-3_CanoR_1 239 245 PF00244 0.541
LIG_14-3-3_CanoR_1 290 294 PF00244 0.435
LIG_Actin_WH2_2 69 87 PF00022 0.589
LIG_APCC_ABBA_1 186 191 PF00400 0.656
LIG_APCC_ABBAyCdc20_2 185 191 PF00400 0.654
LIG_BRCT_BRCA1_1 265 269 PF00533 0.551
LIG_BRCT_BRCA1_1 301 305 PF00533 0.594
LIG_FHA_1 136 142 PF00498 0.808
LIG_FHA_1 176 182 PF00498 0.638
LIG_FHA_1 215 221 PF00498 0.674
LIG_FHA_1 63 69 PF00498 0.553
LIG_FHA_2 11 17 PF00498 0.592
LIG_FHA_2 81 87 PF00498 0.694
LIG_FHA_2 94 100 PF00498 0.641
LIG_GBD_Chelix_1 274 282 PF00786 0.558
LIG_LIR_Gen_1 176 181 PF02991 0.486
LIG_LIR_Nem_3 176 180 PF02991 0.491
LIG_NRBOX 113 119 PF00104 0.676
LIG_PDZ_Class_1 309 314 PF00595 0.521
LIG_Pex14_1 173 177 PF04695 0.562
LIG_PTAP_UEV_1 215 220 PF05743 0.470
LIG_RPA_C_Fungi 279 291 PF08784 0.437
LIG_SH2_CRK 177 181 PF00017 0.532
LIG_SH2_CRK 26 30 PF00017 0.510
LIG_SH2_STAP1 177 181 PF00017 0.545
LIG_SH2_STAT5 177 180 PF00017 0.486
LIG_SH2_STAT5 38 41 PF00017 0.646
LIG_SH3_3 141 147 PF00018 0.578
LIG_SH3_3 213 219 PF00018 0.616
LIG_SUMO_SIM_par_1 166 172 PF11976 0.645
LIG_TYR_ITIM 175 180 PF00017 0.545
LIG_TYR_ITIM 24 29 PF00017 0.644
MOD_CDK_SPxxK_3 143 150 PF00069 0.560
MOD_CK1_1 146 152 PF00069 0.684
MOD_CK1_1 202 208 PF00069 0.599
MOD_CK1_1 241 247 PF00069 0.530
MOD_CK1_1 3 9 PF00069 0.625
MOD_CK1_1 93 99 PF00069 0.691
MOD_CK2_1 154 160 PF00069 0.592
MOD_CK2_1 4 10 PF00069 0.738
MOD_CK2_1 80 86 PF00069 0.598
MOD_CK2_1 93 99 PF00069 0.691
MOD_GlcNHglycan 2 5 PF01048 0.681
MOD_GlcNHglycan 204 207 PF01048 0.705
MOD_GlcNHglycan 258 261 PF01048 0.573
MOD_GlcNHglycan 265 268 PF01048 0.449
MOD_GlcNHglycan 301 304 PF01048 0.513
MOD_GSK3_1 129 136 PF00069 0.693
MOD_GSK3_1 2 9 PF00069 0.666
MOD_GSK3_1 58 65 PF00069 0.542
MOD_GSK3_1 86 93 PF00069 0.716
MOD_N-GLC_1 200 205 PF02516 0.535
MOD_N-GLC_1 299 304 PF02516 0.503
MOD_N-GLC_1 62 67 PF02516 0.641
MOD_NEK2_1 101 106 PF00069 0.560
MOD_NEK2_1 175 180 PF00069 0.423
MOD_NEK2_1 2 7 PF00069 0.641
MOD_NEK2_1 256 261 PF00069 0.555
MOD_PIKK_1 238 244 PF00454 0.563
MOD_PKA_2 231 237 PF00069 0.665
MOD_PKA_2 238 244 PF00069 0.557
MOD_PKA_2 289 295 PF00069 0.450
MOD_PKA_2 90 96 PF00069 0.710
MOD_Plk_1 136 142 PF00069 0.688
MOD_Plk_1 15 21 PF00069 0.594
MOD_Plk_1 175 181 PF00069 0.398
MOD_Plk_1 62 68 PF00069 0.643
MOD_Plk_1 80 86 PF00069 0.404
MOD_Plk_1 91 97 PF00069 0.594
MOD_Plk_2-3 15 21 PF00069 0.628
MOD_Plk_2-3 86 92 PF00069 0.664
MOD_Plk_4 113 119 PF00069 0.630
MOD_Plk_4 136 142 PF00069 0.612
MOD_Plk_4 176 182 PF00069 0.545
MOD_Plk_4 289 295 PF00069 0.469
MOD_ProDKin_1 129 135 PF00069 0.739
MOD_ProDKin_1 143 149 PF00069 0.566
MOD_SUMO_rev_2 70 79 PF00179 0.461
TRG_DiLeu_BaEn_1 53 58 PF01217 0.531
TRG_DiLeu_BaEn_2 264 270 PF01217 0.546
TRG_DiLeu_BaLyEn_6 163 168 PF01217 0.642
TRG_DiLeu_BaLyEn_6 194 199 PF01217 0.539
TRG_DiLeu_BaLyEn_6 64 69 PF01217 0.602
TRG_ENDOCYTIC_2 177 180 PF00928 0.539
TRG_ENDOCYTIC_2 26 29 PF00928 0.605
TRG_ER_diArg_1 183 186 PF00400 0.540
TRG_ER_diArg_1 210 212 PF00400 0.690
TRG_ER_diArg_1 28 31 PF00400 0.611
TRG_ER_diArg_1 282 284 PF00400 0.517
TRG_Pf-PMV_PEXEL_1 243 247 PF00026 0.550
TRG_Pf-PMV_PEXEL_1 295 299 PF00026 0.509
TRG_Pf-PMV_PEXEL_1 55 60 PF00026 0.570

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P6T8 Leptomonas seymouri 32% 100%
A0A3Q8IE11 Leishmania donovani 100% 100%
A4HFJ0 Leishmania braziliensis 66% 100%
E9AD41 Leishmania major 89% 100%
E9AYW5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 87% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS