LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
E9AHD1_LEIIN
TriTrypDb:
LINF_270012100
Length:
462

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 1
GO:0005929 cilium 4 1
GO:0042995 cell projection 2 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0110165 cellular anatomical entity 1 1
GO:0120025 plasma membrane bounded cell projection 3 1
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Expansion

Sequence features

E9AHD1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHD1

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 168 170 PF00675 0.553
CLV_NRD_NRD_1 181 183 PF00675 0.540
CLV_NRD_NRD_1 198 200 PF00675 0.455
CLV_NRD_NRD_1 206 208 PF00675 0.490
CLV_NRD_NRD_1 267 269 PF00675 0.612
CLV_NRD_NRD_1 303 305 PF00675 0.510
CLV_NRD_NRD_1 318 320 PF00675 0.379
CLV_NRD_NRD_1 373 375 PF00675 0.472
CLV_NRD_NRD_1 378 380 PF00675 0.479
CLV_NRD_NRD_1 389 391 PF00675 0.404
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1ILN1 Leptomonas seymouri 60% 100%
A0A1X0P3Z6 Trypanosomatidae 30% 100%
A0A3Q8IE88 Leishmania donovani 100% 100%
A0A3R7MQZ8 Trypanosoma rangeli 33% 100%
A4HFI7 Leishmania braziliensis 74% 100%
D0A5R3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
E9AD38 Leishmania major 93% 100%
E9AYW2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 87% 100%
V5BE50 Trypanosoma cruzi 28% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS