LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
E9AHD1_LEIIN
TriTrypDb:
LINF_270012100
Length:
462

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 1
GO:0005929 cilium 4 1
GO:0042995 cell projection 2 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0110165 cellular anatomical entity 1 1
GO:0120025 plasma membrane bounded cell projection 3 1

Expansion

Sequence features

E9AHD1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHD1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 168 170 PF00675 0.553
CLV_NRD_NRD_1 181 183 PF00675 0.540
CLV_NRD_NRD_1 198 200 PF00675 0.455
CLV_NRD_NRD_1 206 208 PF00675 0.490
CLV_NRD_NRD_1 267 269 PF00675 0.612
CLV_NRD_NRD_1 303 305 PF00675 0.510
CLV_NRD_NRD_1 318 320 PF00675 0.379
CLV_NRD_NRD_1 373 375 PF00675 0.472
CLV_NRD_NRD_1 378 380 PF00675 0.479
CLV_NRD_NRD_1 389 391 PF00675 0.404
CLV_NRD_NRD_1 433 435 PF00675 0.781
CLV_NRD_NRD_1 99 101 PF00675 0.503
CLV_PCSK_FUR_1 371 375 PF00082 0.484
CLV_PCSK_KEX2_1 110 112 PF00082 0.486
CLV_PCSK_KEX2_1 168 170 PF00082 0.469
CLV_PCSK_KEX2_1 238 240 PF00082 0.603
CLV_PCSK_KEX2_1 303 305 PF00082 0.555
CLV_PCSK_KEX2_1 324 326 PF00082 0.472
CLV_PCSK_KEX2_1 373 375 PF00082 0.456
CLV_PCSK_KEX2_1 378 380 PF00082 0.486
CLV_PCSK_KEX2_1 389 391 PF00082 0.539
CLV_PCSK_KEX2_1 433 435 PF00082 0.711
CLV_PCSK_KEX2_1 446 448 PF00082 0.646
CLV_PCSK_KEX2_1 99 101 PF00082 0.490
CLV_PCSK_PC1ET2_1 110 112 PF00082 0.568
CLV_PCSK_PC1ET2_1 238 240 PF00082 0.586
CLV_PCSK_PC1ET2_1 324 326 PF00082 0.491
CLV_PCSK_PC1ET2_1 446 448 PF00082 0.768
CLV_PCSK_PC7_1 369 375 PF00082 0.620
CLV_PCSK_SKI1_1 303 307 PF00082 0.453
CLV_PCSK_SKI1_1 41 45 PF00082 0.554
DEG_APCC_DBOX_1 215 223 PF00400 0.436
DOC_CKS1_1 7 12 PF01111 0.558
DOC_CYCLIN_RxL_1 38 48 PF00134 0.560
DOC_MAPK_gen_1 324 332 PF00069 0.532
DOC_USP7_MATH_1 16 20 PF00917 0.530
DOC_USP7_MATH_1 380 384 PF00917 0.498
DOC_USP7_MATH_1 419 423 PF00917 0.620
DOC_USP7_MATH_1 450 454 PF00917 0.675
DOC_USP7_UBL2_3 17 21 PF12436 0.625
DOC_USP7_UBL2_3 208 212 PF12436 0.585
DOC_USP7_UBL2_3 241 245 PF12436 0.697
DOC_USP7_UBL2_3 320 324 PF12436 0.572
DOC_WW_Pin1_4 441 446 PF00397 0.747
DOC_WW_Pin1_4 453 458 PF00397 0.674
DOC_WW_Pin1_4 6 11 PF00397 0.715
LIG_14-3-3_CanoR_1 250 255 PF00244 0.637
LIG_14-3-3_CanoR_1 433 437 PF00244 0.706
LIG_14-3-3_CanoR_1 63 67 PF00244 0.473
LIG_14-3-3_CanoR_1 76 83 PF00244 0.482
LIG_FHA_1 168 174 PF00498 0.655
LIG_FHA_1 55 61 PF00498 0.595
LIG_FHA_2 435 441 PF00498 0.606
LIG_Integrin_isoDGR_2 137 139 PF01839 0.402
LIG_LIR_Nem_3 32 36 PF02991 0.424
LIG_MYND_1 6 10 PF01753 0.591
LIG_NRBOX 39 45 PF00104 0.547
LIG_PCNA_yPIPBox_3 310 322 PF02747 0.540
LIG_PDZ_Class_2 457 462 PF00595 0.692
LIG_RPA_C_Fungi 364 376 PF08784 0.574
LIG_SH2_CRK 448 452 PF00017 0.575
LIG_SH2_SRC 354 357 PF00017 0.487
LIG_SH2_STAP1 197 201 PF00017 0.585
LIG_SH2_STAP1 33 37 PF00017 0.460
LIG_SH2_STAP1 97 101 PF00017 0.585
LIG_SH2_STAT3 299 302 PF00017 0.458
LIG_SH2_STAT3 36 39 PF00017 0.515
LIG_SH2_STAT5 299 302 PF00017 0.561
LIG_SH2_STAT5 354 357 PF00017 0.557
LIG_SH2_STAT5 36 39 PF00017 0.515
LIG_SH2_STAT5 448 451 PF00017 0.525
LIG_SH3_2 7 12 PF14604 0.509
LIG_SH3_3 4 10 PF00018 0.692
LIG_TRAF2_1 164 167 PF00917 0.580
LIG_TRAF2_1 294 297 PF00917 0.388
LIG_TRAF2_1 309 312 PF00917 0.421
LIG_TRAF2_1 335 338 PF00917 0.549
LIG_ULM_U2AF65_1 238 243 PF00076 0.679
MOD_CDK_SPK_2 441 446 PF00069 0.576
MOD_CDK_SPxK_1 441 447 PF00069 0.578
MOD_CDK_SPxK_1 6 12 PF00069 0.727
MOD_CK1_1 237 243 PF00069 0.699
MOD_CK1_1 432 438 PF00069 0.734
MOD_CK1_1 453 459 PF00069 0.748
MOD_CK2_1 161 167 PF00069 0.596
MOD_CK2_1 332 338 PF00069 0.546
MOD_CK2_1 434 440 PF00069 0.696
MOD_CK2_1 453 459 PF00069 0.743
MOD_GlcNHglycan 334 337 PF01048 0.355
MOD_GlcNHglycan 68 71 PF01048 0.533
MOD_GlcNHglycan 77 80 PF01048 0.524
MOD_GSK3_1 246 253 PF00069 0.628
MOD_GSK3_1 419 426 PF00069 0.659
MOD_GSK3_1 432 439 PF00069 0.683
MOD_GSK3_1 62 69 PF00069 0.567
MOD_N-GLC_1 380 385 PF02516 0.567
MOD_NEK2_1 402 407 PF00069 0.509
MOD_NEK2_1 44 49 PF00069 0.594
MOD_NEK2_1 66 71 PF00069 0.536
MOD_NEK2_2 16 21 PF00069 0.521
MOD_PIKK_1 263 269 PF00454 0.599
MOD_PIKK_1 419 425 PF00454 0.682
MOD_PK_1 250 256 PF00069 0.701
MOD_PKA_1 21 27 PF00069 0.600
MOD_PKA_2 167 173 PF00069 0.644
MOD_PKA_2 234 240 PF00069 0.573
MOD_PKA_2 402 408 PF00069 0.583
MOD_PKA_2 423 429 PF00069 0.703
MOD_PKA_2 432 438 PF00069 0.713
MOD_PKA_2 62 68 PF00069 0.467
MOD_PKA_2 75 81 PF00069 0.492
MOD_Plk_1 155 161 PF00069 0.603
MOD_Plk_1 214 220 PF00069 0.421
MOD_Plk_1 380 386 PF00069 0.465
MOD_Plk_4 155 161 PF00069 0.582
MOD_Plk_4 250 256 PF00069 0.703
MOD_ProDKin_1 441 447 PF00069 0.748
MOD_ProDKin_1 453 459 PF00069 0.676
MOD_ProDKin_1 6 12 PF00069 0.718
MOD_SUMO_for_1 244 247 PF00179 0.707
MOD_SUMO_for_1 407 410 PF00179 0.569
MOD_SUMO_rev_2 135 144 PF00179 0.506
MOD_SUMO_rev_2 226 231 PF00179 0.632
MOD_SUMO_rev_2 287 294 PF00179 0.544
TRG_DiLeu_BaEn_1 301 306 PF01217 0.453
TRG_DiLeu_BaEn_1 356 361 PF01217 0.479
TRG_DiLeu_LyEn_5 301 306 PF01217 0.453
TRG_ENDOCYTIC_2 448 451 PF00928 0.580
TRG_ER_diArg_1 168 171 PF00400 0.549
TRG_ER_diArg_1 216 219 PF00400 0.520
TRG_ER_diArg_1 303 305 PF00400 0.556
TRG_ER_diArg_1 371 374 PF00400 0.490
TRG_ER_diArg_1 388 390 PF00400 0.530
TRG_ER_diArg_1 99 101 PF00400 0.493
TRG_NLS_MonoExtN_4 235 242 PF00514 0.617
TRG_Pf-PMV_PEXEL_1 319 323 PF00026 0.563
TRG_Pf-PMV_PEXEL_1 359 363 PF00026 0.498
TRG_Pf-PMV_PEXEL_1 373 377 PF00026 0.476
TRG_Pf-PMV_PEXEL_1 41 45 PF00026 0.554

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1ILN1 Leptomonas seymouri 60% 100%
A0A1X0P3Z6 Trypanosomatidae 30% 100%
A0A3Q8IE88 Leishmania donovani 100% 100%
A0A3R7MQZ8 Trypanosoma rangeli 33% 100%
A4HFI7 Leishmania braziliensis 74% 100%
D0A5R3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
E9AD38 Leishmania major 93% 100%
E9AYW2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 87% 100%
V5BE50 Trypanosoma cruzi 28% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS