LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
E9AHD0_LEIIN
TriTrypDb:
LINF_270012000
Length:
989

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AHD0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHD0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 4 8 PF00656 0.744
CLV_NRD_NRD_1 326 328 PF00675 0.579
CLV_NRD_NRD_1 343 345 PF00675 0.557
CLV_NRD_NRD_1 360 362 PF00675 0.432
CLV_NRD_NRD_1 417 419 PF00675 0.539
CLV_NRD_NRD_1 436 438 PF00675 0.730
CLV_NRD_NRD_1 505 507 PF00675 0.445
CLV_NRD_NRD_1 561 563 PF00675 0.447
CLV_NRD_NRD_1 716 718 PF00675 0.514
CLV_NRD_NRD_1 724 726 PF00675 0.419
CLV_NRD_NRD_1 729 731 PF00675 0.378
CLV_NRD_NRD_1 752 754 PF00675 0.502
CLV_NRD_NRD_1 776 778 PF00675 0.446
CLV_NRD_NRD_1 884 886 PF00675 0.673
CLV_NRD_NRD_1 983 985 PF00675 0.594
CLV_PCSK_FUR_1 324 328 PF00082 0.565
CLV_PCSK_FUR_1 341 345 PF00082 0.486
CLV_PCSK_FUR_1 699 703 PF00082 0.750
CLV_PCSK_FUR_1 714 718 PF00082 0.395
CLV_PCSK_KEX2_1 324 326 PF00082 0.527
CLV_PCSK_KEX2_1 343 345 PF00082 0.543
CLV_PCSK_KEX2_1 360 362 PF00082 0.507
CLV_PCSK_KEX2_1 417 419 PF00082 0.539
CLV_PCSK_KEX2_1 435 437 PF00082 0.746
CLV_PCSK_KEX2_1 505 507 PF00082 0.495
CLV_PCSK_KEX2_1 563 565 PF00082 0.419
CLV_PCSK_KEX2_1 678 680 PF00082 0.654
CLV_PCSK_KEX2_1 701 703 PF00082 0.593
CLV_PCSK_KEX2_1 716 718 PF00082 0.380
CLV_PCSK_KEX2_1 731 733 PF00082 0.366
CLV_PCSK_KEX2_1 75 77 PF00082 0.679
CLV_PCSK_KEX2_1 752 754 PF00082 0.502
CLV_PCSK_KEX2_1 776 778 PF00082 0.446
CLV_PCSK_KEX2_1 983 985 PF00082 0.590
CLV_PCSK_PC1ET2_1 563 565 PF00082 0.468
CLV_PCSK_PC1ET2_1 678 680 PF00082 0.665
CLV_PCSK_PC1ET2_1 701 703 PF00082 0.633
CLV_PCSK_PC1ET2_1 731 733 PF00082 0.396
CLV_PCSK_PC1ET2_1 75 77 PF00082 0.570
CLV_PCSK_PC7_1 979 985 PF00082 0.540
CLV_PCSK_SKI1_1 303 307 PF00082 0.487
CLV_PCSK_SKI1_1 383 387 PF00082 0.455
CLV_PCSK_SKI1_1 401 405 PF00082 0.470
CLV_PCSK_SKI1_1 417 421 PF00082 0.383
CLV_PCSK_SKI1_1 422 426 PF00082 0.472
CLV_PCSK_SKI1_1 571 575 PF00082 0.455
CLV_PCSK_SKI1_1 606 610 PF00082 0.552
CLV_PCSK_SKI1_1 813 817 PF00082 0.513
CLV_PCSK_SKI1_1 971 975 PF00082 0.537
DEG_APCC_DBOX_1 605 613 PF00400 0.449
DEG_SCF_FBW7_1 650 655 PF00400 0.412
DEG_SCF_FBW7_1 852 857 PF00400 0.530
DEG_SPOP_SBC_1 77 81 PF00917 0.648
DEG_SPOP_SBC_1 824 828 PF00917 0.548
DOC_CKS1_1 131 136 PF01111 0.541
DOC_CKS1_1 190 195 PF01111 0.651
DOC_CKS1_1 839 844 PF01111 0.609
DOC_CYCLIN_RxL_1 380 389 PF00134 0.522
DOC_CYCLIN_RxL_1 809 820 PF00134 0.614
DOC_CYCLIN_yCln2_LP_2 261 267 PF00134 0.507
DOC_MAPK_gen_1 303 312 PF00069 0.507
DOC_MAPK_gen_1 548 558 PF00069 0.526
DOC_MAPK_gen_1 966 975 PF00069 0.463
DOC_MAPK_MEF2A_6 760 767 PF00069 0.568
DOC_PP4_FxxP_1 25 28 PF00568 0.590
DOC_USP7_MATH_1 104 108 PF00917 0.766
DOC_USP7_MATH_1 157 161 PF00917 0.737
DOC_USP7_MATH_1 165 169 PF00917 0.658
DOC_USP7_MATH_1 172 176 PF00917 0.574
DOC_USP7_MATH_1 181 185 PF00917 0.587
DOC_USP7_MATH_1 227 231 PF00917 0.685
DOC_USP7_MATH_1 284 288 PF00917 0.667
DOC_USP7_MATH_1 478 482 PF00917 0.659
DOC_USP7_MATH_1 52 56 PF00917 0.743
DOC_USP7_MATH_1 652 656 PF00917 0.540
DOC_USP7_MATH_1 766 770 PF00917 0.506
DOC_USP7_MATH_1 77 81 PF00917 0.776
DOC_USP7_MATH_1 792 796 PF00917 0.582
DOC_USP7_MATH_1 798 802 PF00917 0.576
DOC_USP7_MATH_1 854 858 PF00917 0.607
DOC_USP7_MATH_1 872 876 PF00917 0.508
DOC_USP7_MATH_1 902 906 PF00917 0.652
DOC_USP7_MATH_1 933 937 PF00917 0.655
DOC_USP7_MATH_1 940 944 PF00917 0.637
DOC_USP7_UBL2_3 6 10 PF12436 0.606
DOC_WW_Pin1_4 11 16 PF00397 0.615
DOC_WW_Pin1_4 130 135 PF00397 0.554
DOC_WW_Pin1_4 140 145 PF00397 0.725
DOC_WW_Pin1_4 163 168 PF00397 0.789
DOC_WW_Pin1_4 173 178 PF00397 0.773
DOC_WW_Pin1_4 186 191 PF00397 0.580
DOC_WW_Pin1_4 196 201 PF00397 0.637
DOC_WW_Pin1_4 333 338 PF00397 0.489
DOC_WW_Pin1_4 396 401 PF00397 0.532
DOC_WW_Pin1_4 436 441 PF00397 0.652
DOC_WW_Pin1_4 45 50 PF00397 0.794
DOC_WW_Pin1_4 5 10 PF00397 0.680
DOC_WW_Pin1_4 648 653 PF00397 0.533
DOC_WW_Pin1_4 690 695 PF00397 0.627
DOC_WW_Pin1_4 83 88 PF00397 0.799
DOC_WW_Pin1_4 838 843 PF00397 0.666
DOC_WW_Pin1_4 850 855 PF00397 0.579
DOC_WW_Pin1_4 860 865 PF00397 0.564
DOC_WW_Pin1_4 959 964 PF00397 0.476
DOC_WW_Pin1_4 98 103 PF00397 0.656
LIG_14-3-3_CanoR_1 183 193 PF00244 0.652
LIG_14-3-3_CanoR_1 262 268 PF00244 0.504
LIG_14-3-3_CanoR_1 343 349 PF00244 0.589
LIG_14-3-3_CanoR_1 383 388 PF00244 0.451
LIG_14-3-3_CanoR_1 401 407 PF00244 0.460
LIG_14-3-3_CanoR_1 594 598 PF00244 0.493
LIG_14-3-3_CanoR_1 629 638 PF00244 0.415
LIG_14-3-3_CanoR_1 669 677 PF00244 0.717
LIG_14-3-3_CanoR_1 818 825 PF00244 0.757
LIG_14-3-3_CanoR_1 831 839 PF00244 0.677
LIG_14-3-3_CanoR_1 911 917 PF00244 0.648
LIG_BIR_III_2 482 486 PF00653 0.510
LIG_BRCT_BRCA1_1 167 171 PF00533 0.645
LIG_BRCT_BRCA1_1 378 382 PF00533 0.515
LIG_CtBP_PxDLS_1 951 955 PF00389 0.498
LIG_eIF4E_1 569 575 PF01652 0.419
LIG_FHA_1 141 147 PF00498 0.639
LIG_FHA_1 32 38 PF00498 0.622
LIG_FHA_1 387 393 PF00498 0.558
LIG_FHA_1 497 503 PF00498 0.591
LIG_FHA_1 762 768 PF00498 0.541
LIG_FHA_1 818 824 PF00498 0.557
LIG_FHA_2 410 416 PF00498 0.422
LIG_FHA_2 511 517 PF00498 0.386
LIG_FHA_2 631 637 PF00498 0.433
LIG_FHA_2 768 774 PF00498 0.541
LIG_FHA_2 79 85 PF00498 0.703
LIG_FHA_2 960 966 PF00498 0.567
LIG_KLC1_Yacidic_2 294 298 PF13176 0.528
LIG_LIR_Apic_2 24 28 PF02991 0.543
LIG_LIR_Gen_1 106 117 PF02991 0.447
LIG_LIR_Gen_1 404 414 PF02991 0.460
LIG_LIR_Gen_1 634 645 PF02991 0.393
LIG_LIR_Nem_3 106 112 PF02991 0.468
LIG_LIR_Nem_3 379 385 PF02991 0.487
LIG_LIR_Nem_3 404 410 PF02991 0.469
LIG_LIR_Nem_3 568 573 PF02991 0.450
LIG_LIR_Nem_3 634 640 PF02991 0.394
LIG_RPA_C_Fungi 871 883 PF08784 0.508
LIG_SH2_CRK 570 574 PF00017 0.444
LIG_SH2_NCK_1 411 415 PF00017 0.519
LIG_SH2_SRC 296 299 PF00017 0.459
LIG_SH2_STAP1 244 248 PF00017 0.626
LIG_SH2_STAP1 338 342 PF00017 0.459
LIG_SH2_STAP1 479 483 PF00017 0.596
LIG_SH2_STAT3 745 748 PF00017 0.586
LIG_SH2_STAT5 130 133 PF00017 0.538
LIG_SH2_STAT5 296 299 PF00017 0.633
LIG_SH2_STAT5 411 414 PF00017 0.588
LIG_SH2_STAT5 644 647 PF00017 0.474
LIG_SH2_STAT5 745 748 PF00017 0.586
LIG_SH2_STAT5 779 782 PF00017 0.398
LIG_SH3_1 235 241 PF00018 0.521
LIG_SH3_1 327 333 PF00018 0.476
LIG_SH3_1 659 665 PF00018 0.491
LIG_SH3_1 885 891 PF00018 0.626
LIG_SH3_2 147 152 PF14604 0.598
LIG_SH3_2 888 893 PF14604 0.629
LIG_SH3_3 128 134 PF00018 0.536
LIG_SH3_3 141 147 PF00018 0.728
LIG_SH3_3 187 193 PF00018 0.624
LIG_SH3_3 235 241 PF00018 0.633
LIG_SH3_3 327 333 PF00018 0.476
LIG_SH3_3 43 49 PF00018 0.681
LIG_SH3_3 659 665 PF00018 0.548
LIG_SH3_3 760 766 PF00018 0.464
LIG_SH3_3 836 842 PF00018 0.658
LIG_SH3_3 885 891 PF00018 0.626
LIG_SH3_3 914 920 PF00018 0.676
LIG_SUMO_SIM_anti_2 636 642 PF11976 0.441
LIG_SUMO_SIM_par_1 383 389 PF11976 0.542
LIG_SUMO_SIM_par_1 498 504 PF11976 0.579
LIG_TRAF2_1 315 318 PF00917 0.551
LIG_WW_3 661 665 PF00397 0.418
MOD_CDC14_SPxK_1 439 442 PF00782 0.644
MOD_CDK_SPK_2 396 401 PF00069 0.532
MOD_CDK_SPK_2 5 10 PF00069 0.630
MOD_CDK_SPxK_1 436 442 PF00069 0.629
MOD_CDK_SPxxK_3 838 845 PF00069 0.778
MOD_CDK_SPxxK_3 959 966 PF00069 0.538
MOD_CK1_1 107 113 PF00069 0.670
MOD_CK1_1 14 20 PF00069 0.692
MOD_CK1_1 160 166 PF00069 0.733
MOD_CK1_1 184 190 PF00069 0.676
MOD_CK1_1 501 507 PF00069 0.468
MOD_CK1_1 673 679 PF00069 0.755
MOD_CK1_1 689 695 PF00069 0.545
MOD_CK1_1 769 775 PF00069 0.493
MOD_CK1_1 863 869 PF00069 0.770
MOD_CK1_1 936 942 PF00069 0.669
MOD_CK2_1 250 256 PF00069 0.548
MOD_CK2_1 409 415 PF00069 0.481
MOD_CK2_1 510 516 PF00069 0.384
MOD_CK2_1 610 616 PF00069 0.396
MOD_CK2_1 630 636 PF00069 0.538
MOD_CK2_1 767 773 PF00069 0.550
MOD_CK2_1 78 84 PF00069 0.702
MOD_CK2_1 824 830 PF00069 0.616
MOD_CK2_1 950 956 PF00069 0.609
MOD_CK2_1 958 964 PF00069 0.580
MOD_Cter_Amidation 72 75 PF01082 0.661
MOD_Cter_Amidation 883 886 PF01082 0.630
MOD_DYRK1A_RPxSP_1 838 842 PF00069 0.627
MOD_GlcNHglycan 135 138 PF01048 0.679
MOD_GlcNHglycan 159 162 PF01048 0.715
MOD_GlcNHglycan 245 248 PF01048 0.614
MOD_GlcNHglycan 274 277 PF01048 0.744
MOD_GlcNHglycan 462 465 PF01048 0.700
MOD_GlcNHglycan 513 516 PF01048 0.585
MOD_GlcNHglycan 612 615 PF01048 0.451
MOD_GlcNHglycan 654 657 PF01048 0.553
MOD_GlcNHglycan 672 675 PF01048 0.515
MOD_GlcNHglycan 681 684 PF01048 0.758
MOD_GlcNHglycan 688 691 PF01048 0.552
MOD_GlcNHglycan 780 783 PF01048 0.562
MOD_GlcNHglycan 800 803 PF01048 0.630
MOD_GlcNHglycan 833 836 PF01048 0.710
MOD_GlcNHglycan 856 859 PF01048 0.790
MOD_GlcNHglycan 870 873 PF01048 0.627
MOD_GlcNHglycan 878 881 PF01048 0.727
MOD_GlcNHglycan 905 908 PF01048 0.676
MOD_GlcNHglycan 914 917 PF01048 0.607
MOD_GlcNHglycan 936 939 PF01048 0.738
MOD_GlcNHglycan 984 987 PF01048 0.577
MOD_GSK3_1 129 136 PF00069 0.761
MOD_GSK3_1 156 163 PF00069 0.791
MOD_GSK3_1 182 189 PF00069 0.572
MOD_GSK3_1 213 220 PF00069 0.627
MOD_GSK3_1 223 230 PF00069 0.585
MOD_GSK3_1 239 246 PF00069 0.657
MOD_GSK3_1 26 33 PF00069 0.575
MOD_GSK3_1 272 279 PF00069 0.581
MOD_GSK3_1 456 463 PF00069 0.550
MOD_GSK3_1 648 655 PF00069 0.602
MOD_GSK3_1 686 693 PF00069 0.655
MOD_GSK3_1 792 799 PF00069 0.638
MOD_GSK3_1 825 832 PF00069 0.731
MOD_GSK3_1 850 857 PF00069 0.664
MOD_GSK3_1 868 875 PF00069 0.516
MOD_GSK3_1 903 910 PF00069 0.553
MOD_GSK3_1 936 943 PF00069 0.549
MOD_GSK3_1 94 101 PF00069 0.740
MOD_N-GLC_1 805 810 PF02516 0.509
MOD_N-GLC_2 59 61 PF02516 0.683
MOD_NEK2_1 201 206 PF00069 0.612
MOD_NEK2_1 31 36 PF00069 0.677
MOD_NEK2_1 784 789 PF00069 0.418
MOD_NEK2_1 805 810 PF00069 0.618
MOD_NEK2_2 402 407 PF00069 0.492
MOD_PIKK_1 213 219 PF00454 0.613
MOD_PIKK_1 26 32 PF00454 0.601
MOD_PIKK_1 266 272 PF00454 0.630
MOD_PIKK_1 725 731 PF00454 0.543
MOD_PKA_1 367 373 PF00069 0.441
MOD_PKA_1 725 731 PF00069 0.431
MOD_PKA_2 182 188 PF00069 0.743
MOD_PKA_2 31 37 PF00069 0.699
MOD_PKA_2 593 599 PF00069 0.458
MOD_PKA_2 767 773 PF00069 0.472
MOD_PKA_2 817 823 PF00069 0.697
MOD_PKA_2 933 939 PF00069 0.617
MOD_PKA_2 940 946 PF00069 0.602
MOD_PKA_2 982 988 PF00069 0.529
MOD_PKB_1 829 837 PF00069 0.765
MOD_Plk_1 743 749 PF00069 0.725
MOD_Plk_1 761 767 PF00069 0.405
MOD_Plk_1 872 878 PF00069 0.500
MOD_Plk_1 94 100 PF00069 0.709
MOD_Plk_2-3 409 415 PF00069 0.415
MOD_Plk_2-3 950 956 PF00069 0.531
MOD_Plk_4 239 245 PF00069 0.498
MOD_Plk_4 402 408 PF00069 0.518
MOD_Plk_4 792 798 PF00069 0.512
MOD_Plk_4 950 956 PF00069 0.583
MOD_ProDKin_1 130 136 PF00069 0.555
MOD_ProDKin_1 140 146 PF00069 0.726
MOD_ProDKin_1 163 169 PF00069 0.731
MOD_ProDKin_1 173 179 PF00069 0.772
MOD_ProDKin_1 186 192 PF00069 0.579
MOD_ProDKin_1 196 202 PF00069 0.634
MOD_ProDKin_1 333 339 PF00069 0.482
MOD_ProDKin_1 396 402 PF00069 0.525
MOD_ProDKin_1 436 442 PF00069 0.655
MOD_ProDKin_1 45 51 PF00069 0.795
MOD_ProDKin_1 5 11 PF00069 0.679
MOD_ProDKin_1 648 654 PF00069 0.538
MOD_ProDKin_1 690 696 PF00069 0.628
MOD_ProDKin_1 83 89 PF00069 0.801
MOD_ProDKin_1 838 844 PF00069 0.665
MOD_ProDKin_1 850 856 PF00069 0.576
MOD_ProDKin_1 860 866 PF00069 0.565
MOD_ProDKin_1 959 965 PF00069 0.470
MOD_ProDKin_1 98 104 PF00069 0.655
MOD_SUMO_for_1 538 541 PF00179 0.499
MOD_SUMO_for_1 700 703 PF00179 0.655
MOD_SUMO_rev_2 421 426 PF00179 0.497
MOD_SUMO_rev_2 557 565 PF00179 0.565
TRG_DiLeu_BaEn_1 616 621 PF01217 0.463
TRG_DiLeu_BaEn_1 950 955 PF01217 0.534
TRG_DiLeu_BaLyEn_6 750 755 PF01217 0.591
TRG_ENDOCYTIC_2 109 112 PF00928 0.636
TRG_ENDOCYTIC_2 570 573 PF00928 0.453
TRG_ER_diArg_1 324 327 PF00400 0.568
TRG_ER_diArg_1 341 344 PF00400 0.543
TRG_ER_diArg_1 359 361 PF00400 0.547
TRG_ER_diArg_1 435 437 PF00400 0.758
TRG_ER_diArg_1 465 468 PF00400 0.550
TRG_ER_diArg_1 505 507 PF00400 0.569
TRG_ER_diArg_1 562 565 PF00400 0.454
TRG_ER_diArg_1 713 716 PF00400 0.515
TRG_ER_diArg_1 751 753 PF00400 0.510
TRG_ER_diArg_1 775 777 PF00400 0.448
TRG_ER_diArg_1 966 969 PF00400 0.610
TRG_NLS_Bipartite_1 716 734 PF00514 0.344
TRG_Pf-PMV_PEXEL_1 579 583 PF00026 0.477
TRG_Pf-PMV_PEXEL_1 732 736 PF00026 0.467

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PC69 Leptomonas seymouri 47% 95%
A0A1X0P481 Trypanosomatidae 29% 100%
A0A3R7NHW7 Trypanosoma rangeli 31% 100%
A0A3S7X0G5 Leishmania donovani 99% 100%
A4HFI6 Leishmania braziliensis 68% 99%
E9AD37 Leishmania major 88% 100%
E9AYW1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 83% 96%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS