FGGY_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AHA7_LEIIN

TriTrypDb:

LINF_260005700

Length:

269

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AHA7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AHA7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	260	264	PF00656	0.433
CLV_NRD_NRD_1	183	185	PF00675	0.496
CLV_NRD_NRD_1	190	192	PF00675	0.549
CLV_NRD_NRD_1	225	227	PF00675	0.408
CLV_PCSK_KEX2_1	227	229	PF00082	0.442
CLV_PCSK_PC1ET2_1	227	229	PF00082	0.478
CLV_PCSK_SKI1_1	123	127	PF00082	0.459
CLV_PCSK_SKI1_1	70	74	PF00082	0.416
DEG_Nend_UBRbox_2	1	3	PF02207	0.541
DEG_SPOP_SBC_1	101	105	PF00917	0.416
DOC_CKS1_1	136	141	PF01111	0.454
DOC_MAPK_MEF2A_6	14	21	PF00069	0.403
DOC_MAPK_MEF2A_6	250	257	PF00069	0.396
DOC_MAPK_NFAT4_5	250	258	PF00069	0.389
DOC_PP1_RVXF_1	175	182	PF00149	0.462
DOC_PP2B_LxvP_1	47	50	PF13499	0.509
DOC_PP4_FxxP_1	136	139	PF00568	0.450
DOC_USP7_MATH_1	197	201	PF00917	0.674
DOC_WW_Pin1_4	135	140	PF00397	0.353
LIG_14-3-3_CanoR_1	14	20	PF00244	0.405
LIG_14-3-3_CanoR_1	70	80	PF00244	0.345
LIG_deltaCOP1_diTrp_1	150	159	PF00928	0.371
LIG_FHA_1	102	108	PF00498	0.500
LIG_FHA_1	135	141	PF00498	0.361
LIG_FHA_1	234	240	PF00498	0.364
LIG_FHA_1	66	72	PF00498	0.432
LIG_FHA_1	73	79	PF00498	0.388
LIG_FHA_2	207	213	PF00498	0.506
LIG_FHA_2	41	47	PF00498	0.485
LIG_GBD_Chelix_1	253	261	PF00786	0.426
LIG_LIR_Apic_2	81	87	PF02991	0.476
LIG_LIR_Gen_1	158	167	PF02991	0.429
LIG_LIR_Gen_1	212	223	PF02991	0.461
LIG_LIR_LC3C_4	124	128	PF02991	0.342
LIG_LIR_Nem_3	150	156	PF02991	0.595
LIG_LIR_Nem_3	158	162	PF02991	0.529
LIG_LIR_Nem_3	168	174	PF02991	0.297
LIG_LIR_Nem_3	212	218	PF02991	0.493
LIG_NRBOX	57	63	PF00104	0.473
LIG_PDZ_Wminus1_1	267	269	PF00595	0.412
LIG_Rb_LxCxE_1	206	219	PF01857	0.446
LIG_SH2_CRK	90	94	PF00017	0.453
LIG_SH2_STAP1	90	94	PF00017	0.453
LIG_SH2_STAT5	90	93	PF00017	0.392
LIG_SH3_3	159	165	PF00018	0.596
LIG_SH3_3	241	247	PF00018	0.476
LIG_SUMO_SIM_anti_2	73	81	PF11976	0.380
LIG_SUMO_SIM_par_1	73	81	PF11976	0.404
LIG_TYR_ITIM	88	93	PF00017	0.474
LIG_UBA3_1	178	185	PF00899	0.376
LIG_WRC_WIRS_1	156	161	PF05994	0.424
MOD_CK1_1	15	21	PF00069	0.385
MOD_CK1_1	195	201	PF00069	0.624
MOD_CK2_1	144	150	PF00069	0.458
MOD_CK2_1	20	26	PF00069	0.447
MOD_CK2_1	206	212	PF00069	0.487
MOD_CK2_1	40	46	PF00069	0.303
MOD_GlcNHglycan	123	126	PF01048	0.514
MOD_GlcNHglycan	199	202	PF01048	0.602
MOD_GlcNHglycan	23	26	PF01048	0.620
MOD_GlcNHglycan	257	260	PF01048	0.499
MOD_GSK3_1	101	108	PF00069	0.423
MOD_GSK3_1	144	151	PF00069	0.417
MOD_GSK3_1	15	22	PF00069	0.398
MOD_GSK3_1	257	264	PF00069	0.468
MOD_NEK2_1	12	17	PF00069	0.407
MOD_NEK2_1	255	260	PF00069	0.403
MOD_NEK2_1	64	69	PF00069	0.385
MOD_NEK2_1	71	76	PF00069	0.410
MOD_NEK2_1	80	85	PF00069	0.362
MOD_NEK2_1	88	93	PF00069	0.469
MOD_PIKK_1	105	111	PF00454	0.454
MOD_PIKK_1	72	78	PF00454	0.409
MOD_PKA_2	52	58	PF00069	0.494
MOD_Plk_4	148	154	PF00069	0.501
MOD_Plk_4	155	161	PF00069	0.507
MOD_Plk_4	203	209	PF00069	0.598
MOD_Plk_4	233	239	PF00069	0.373
MOD_Plk_4	261	267	PF00069	0.443
MOD_Plk_4	88	94	PF00069	0.468
MOD_ProDKin_1	135	141	PF00069	0.359
TRG_DiLeu_BaEn_1	248	253	PF01217	0.345
TRG_DiLeu_BaLyEn_6	174	179	PF01217	0.545
TRG_DiLeu_BaLyEn_6	57	62	PF01217	0.382
TRG_ENDOCYTIC_2	90	93	PF00928	0.371
TRG_NES_CRM1_1	229	243	PF08389	0.438

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I2Y9	Leptomonas seymouri	33%	95%
A0A3Q8IDH0	Leishmania donovani	100%	100%
E9ACT2	Leishmania major	90%	100%
E9AIR8	Leishmania braziliensis	65%	100%
E9AXZ0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%