LeishMANIAdb
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WW domain binding protein 1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
WW domain binding protein 1
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
E9AH55_LEIIN
TriTrypDb:
LINF_240010400
Length:
130

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
Term Name Level Count
GO:0016020 membrane 2 5
GO:0110165 cellular anatomical entity 1 5

Expansion

Sequence features

E9AH55
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AH55

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 16 20 PF00656 0.458
CLV_NRD_NRD_1 73 75 PF00675 0.428
CLV_NRD_NRD_1 91 93 PF00675 0.482
CLV_NRD_NRD_1 94 96 PF00675 0.451
CLV_PCSK_FUR_1 71 75 PF00082 0.423
CLV_PCSK_FUR_1 92 96 PF00082 0.421
CLV_PCSK_KEX2_1 73 75 PF00082 0.428
CLV_PCSK_KEX2_1 90 92 PF00082 0.551
CLV_PCSK_KEX2_1 94 96 PF00082 0.449
CLV_PCSK_PC7_1 90 96 PF00082 0.409
CLV_PCSK_SKI1_1 73 77 PF00082 0.397
DOC_PP2B_LxvP_1 115 118 PF13499 0.693
DOC_USP7_MATH_1 107 111 PF00917 0.734
DOC_USP7_MATH_1 21 25 PF00917 0.403
DOC_WW_Pin1_4 32 37 PF00397 0.488
LIG_14-3-3_CanoR_1 14 21 PF00244 0.400
LIG_14-3-3_CanoR_1 77 82 PF00244 0.640
LIG_14-3-3_CanoR_1 92 102 PF00244 0.627
LIG_APCC_ABBA_1 67 72 PF00400 0.498
LIG_BIR_II_1 1 5 PF00653 0.429
LIG_FHA_1 112 118 PF00498 0.647
LIG_FHA_2 1 7 PF00498 0.485
LIG_FHA_2 14 20 PF00498 0.352
LIG_LIR_Nem_3 40 45 PF02991 0.423
LIG_SH2_CRK 42 46 PF00017 0.446
LIG_SH2_CRK 79 83 PF00017 0.570
LIG_SH2_STAP1 37 41 PF00017 0.475
LIG_SH2_STAT5 15 18 PF00017 0.394
LIG_SH2_STAT5 79 82 PF00017 0.611
LIG_SH3_3 101 107 PF00018 0.730
MOD_CK1_1 122 128 PF00069 0.683
MOD_CK2_1 107 113 PF00069 0.655
MOD_GlcNHglycan 109 112 PF01048 0.551
MOD_GSK3_1 107 114 PF00069 0.680
MOD_GSK3_1 21 28 PF00069 0.427
MOD_N-GLC_2 29 31 PF02516 0.596
MOD_NEK2_2 111 116 PF00069 0.652
MOD_NEK2_2 13 18 PF00069 0.398
MOD_PIKK_1 117 123 PF00454 0.683
MOD_PKA_2 122 128 PF00069 0.680
MOD_PKA_2 13 19 PF00069 0.399
MOD_PKA_2 21 27 PF00069 0.397
MOD_PKA_2 93 99 PF00069 0.649
MOD_Plk_4 77 83 PF00069 0.612
MOD_ProDKin_1 32 38 PF00069 0.489
MOD_SUMO_for_1 82 85 PF00179 0.618
TRG_ENDOCYTIC_2 42 45 PF00928 0.463
TRG_ENDOCYTIC_2 79 82 PF00928 0.585
TRG_ER_diArg_1 90 92 PF00400 0.640

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1P9I9 Leptomonas seymouri 43% 100%
A0A3S7WY70 Leishmania donovani 99% 100%
A4HDB4 Leishmania braziliensis 69% 100%
E9ACS7 Leishmania major 94% 100%
E9AWP6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS