WD repeat protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

WD repeat protein

Gene product:

WD repeat protein

Species:

Leishmania infantum

UniProt:

E9AH35_LEIIN

TriTrypDb:

LINF_240007100

Length:

467

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Show entries

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Previous1Next

Expansion

Sequence features

E9AH35

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AH35

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0006325	chromatin organization	4	1
GO:0006338	chromatin remodeling	5	1
GO:0006355	regulation of DNA-templated transcription	6	1
GO:0009889	regulation of biosynthetic process	4	1
GO:0009987	cellular process	1	1
GO:0010468	regulation of gene expression	5	1
GO:0010556	regulation of macromolecule biosynthetic process	5	1
GO:0016043	cellular component organization	3	1
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	1
GO:0019222	regulation of metabolic process	3	1

Previous1 2 3Next

Show entries

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	1
GO:0005515	protein binding	2	1
GO:0042393	histone binding	3	1

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	143	145	PF00675	0.400
CLV_NRD_NRD_1	233	235	PF00675	0.544
CLV_NRD_NRD_1	45	47	PF00675	0.265
CLV_PCSK_KEX2_1	143	145	PF00082	0.400
CLV_PCSK_KEX2_1	216	218	PF00082	0.446
CLV_PCSK_KEX2_1	233	235	PF00082	0.522
CLV_PCSK_PC1ET2_1	216	218	PF00082	0.481
CLV_PCSK_SKI1_1	143	147	PF00082	0.375
CLV_PCSK_SKI1_1	399	403	PF00082	0.373
CLV_PCSK_SKI1_1	420	424	PF00082	0.366

Previous1 2 3 4 5…16Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILV6	Leptomonas seymouri	79%	100%
A0A0S4J9M2	Bodo saltans	49%	94%
A0A1X0NIM0	Trypanosomatidae	57%	100%
A0A3Q8IMH5	Leishmania donovani	100%	79%
A0A3R7LDW9	Trypanosoma rangeli	59%	100%
A4HD80	Leishmania braziliensis	90%	100%
D0A6Z2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	55%	100%
E9AWL3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
O22466	Solanum lycopersicum	24%	100%
O22467	Arabidopsis thaliana	24%	100%

Previous1 2 3 4 5 6Next