Ubiquitin-like domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AH33_LEIIN

TriTrypDb:

LINF_240006900

Length:

340

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AH33

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AH33

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	17	21	PF00656	0.468
CLV_MEL_PAP_1	36	42	PF00089	0.384
CLV_NRD_NRD_1	146	148	PF00675	0.682
CLV_NRD_NRD_1	195	197	PF00675	0.407
CLV_PCSK_KEX2_1	146	148	PF00082	0.597
CLV_PCSK_SKI1_1	139	143	PF00082	0.526
CLV_PCSK_SKI1_1	318	322	PF00082	0.652
CLV_PCSK_SKI1_1	6	10	PF00082	0.472
DEG_Nend_UBRbox_1	1	4	PF02207	0.325
DOC_CKS1_1	220	225	PF01111	0.586
DOC_CKS1_1	273	278	PF01111	0.512
DOC_CYCLIN_yCln2_LP_2	273	279	PF00134	0.461
DOC_MAPK_gen_1	272	279	PF00069	0.468
DOC_MAPK_MEF2A_6	33	40	PF00069	0.400
DOC_MAPK_RevD_3	131	147	PF00069	0.510
DOC_PP2B_LxvP_1	133	136	PF13499	0.509
DOC_USP7_UBL2_3	115	119	PF12436	0.535
DOC_WW_Pin1_4	21	26	PF00397	0.470
DOC_WW_Pin1_4	219	224	PF00397	0.557
DOC_WW_Pin1_4	272	277	PF00397	0.484
LIG_14-3-3_CanoR_1	12	16	PF00244	0.327
LIG_14-3-3_CanoR_1	2	6	PF00244	0.388
LIG_14-3-3_CanoR_1	39	49	PF00244	0.429
LIG_AP2alpha_2	224	226	PF02296	0.536
LIG_BIR_III_4	152	156	PF00653	0.659
LIG_Clathr_ClatBox_1	48	52	PF01394	0.461
LIG_FHA_1	56	62	PF00498	0.550
LIG_FHA_1	74	80	PF00498	0.291
LIG_FHA_2	26	32	PF00498	0.374
LIG_FHA_2	94	100	PF00498	0.626
LIG_FXI_DFP_1	245	249	PF00024	0.421
LIG_G3BP_FGDF_1	243	248	PF02136	0.372
LIG_LIR_Gen_1	10	21	PF02991	0.447
LIG_LIR_Gen_1	182	193	PF02991	0.479
LIG_LIR_Gen_1	224	234	PF02991	0.479
LIG_LIR_Gen_1	247	255	PF02991	0.400
LIG_LIR_Gen_1	305	314	PF02991	0.404
LIG_LIR_Nem_3	10	16	PF02991	0.432
LIG_LIR_Nem_3	182	188	PF02991	0.407
LIG_LIR_Nem_3	224	229	PF02991	0.655
LIG_LIR_Nem_3	247	251	PF02991	0.391
LIG_LIR_Nem_3	305	311	PF02991	0.380
LIG_LYPXL_S_1	285	289	PF13949	0.358
LIG_LYPXL_yS_3	208	211	PF13949	0.372
LIG_LYPXL_yS_3	286	289	PF13949	0.346
LIG_NRBOX	50	56	PF00104	0.496
LIG_Pex14_2	307	311	PF04695	0.375
LIG_SH2_CRK	185	189	PF00017	0.468
LIG_SH2_NCK_1	13	17	PF00017	0.414
LIG_SH2_SRC	185	188	PF00017	0.498
LIG_SH2_STAT5	244	247	PF00017	0.375
LIG_SH3_3	118	124	PF00018	0.522
LIG_SH3_3	156	162	PF00018	0.671
LIG_SH3_3	208	214	PF00018	0.479
LIG_SH3_3	67	73	PF00018	0.475
LIG_SUMO_SIM_anti_2	46	52	PF11976	0.366
LIG_SUMO_SIM_anti_2	63	68	PF11976	0.384
LIG_SUMO_SIM_par_1	291	297	PF11976	0.348
LIG_SUMO_SIM_par_1	46	52	PF11976	0.458
LIG_SUMO_SIM_par_1	56	63	PF11976	0.473
LIG_TYR_ITIM	206	211	PF00017	0.368
LIG_UBA3_1	111	119	PF00899	0.445
MOD_CK1_1	24	30	PF00069	0.440
MOD_CK1_1	264	270	PF00069	0.443
MOD_CK2_1	11	17	PF00069	0.430
MOD_CK2_1	25	31	PF00069	0.294
MOD_CK2_1	40	46	PF00069	0.389
MOD_CK2_1	80	86	PF00069	0.600
MOD_GlcNHglycan	315	318	PF01048	0.570
MOD_GlcNHglycan	331	334	PF01048	0.686
MOD_GSK3_1	21	28	PF00069	0.367
MOD_GSK3_1	7	14	PF00069	0.389
MOD_NEK2_1	1	6	PF00069	0.388
MOD_NEK2_1	40	45	PF00069	0.455
MOD_NEK2_1	55	60	PF00069	0.436
MOD_NEK2_1	85	90	PF00069	0.626
MOD_PK_1	62	68	PF00069	0.411
MOD_PKA_2	1	7	PF00069	0.388
MOD_PKA_2	11	17	PF00069	0.337
MOD_PKA_2	80	86	PF00069	0.519
MOD_Plk_1	25	31	PF00069	0.523
MOD_Plk_1	55	61	PF00069	0.452
MOD_Plk_4	11	17	PF00069	0.366
MOD_Plk_4	62	68	PF00069	0.414
MOD_Plk_4	80	86	PF00069	0.431
MOD_ProDKin_1	21	27	PF00069	0.463
MOD_ProDKin_1	219	225	PF00069	0.571
MOD_ProDKin_1	272	278	PF00069	0.487
MOD_SUMO_rev_2	26	35	PF00179	0.438
TRG_DiLeu_BaEn_1	31	36	PF01217	0.358
TRG_DiLeu_BaLyEn_6	284	289	PF01217	0.466
TRG_ENDOCYTIC_2	13	16	PF00928	0.406
TRG_ENDOCYTIC_2	185	188	PF00928	0.404
TRG_ENDOCYTIC_2	208	211	PF00928	0.372
TRG_ENDOCYTIC_2	286	289	PF00928	0.346
TRG_ER_diArg_1	136	139	PF00400	0.433
TRG_ER_diArg_1	271	274	PF00400	0.464

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7K8	Leptomonas seymouri	68%	100%
A0A0S4JUQ7	Bodo saltans	38%	100%
A0A1X0NIQ0	Trypanosomatidae	46%	100%
A0A3Q8IBY8	Leishmania donovani	99%	100%
E9AWL1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q4QAV9	Leishmania major	94%	100%