Uncharacterized protein

Quick info Localization Phosphorylation Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Phosducin - putative

Species:

Leishmania infantum

UniProt:

E9AH28_LEIIN

TriTrypDb:

LINF_240006400

Length:

241

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	1

Phosphorylation

Promastigote: 84

Expansion

Sequence features

E9AH28

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AH28

Function

Biological processes
Term	Name	Level	Count
GO:0006457	protein folding	2	1
GO:0009987	cellular process	1	1

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	161	163	PF00675	0.334
CLV_NRD_NRD_1	97	99	PF00675	0.260
CLV_PCSK_FUR_1	95	99	PF00082	0.250
CLV_PCSK_KEX2_1	160	162	PF00082	0.327
CLV_PCSK_KEX2_1	208	210	PF00082	0.274
CLV_PCSK_KEX2_1	95	97	PF00082	0.252
CLV_PCSK_PC1ET2_1	208	210	PF00082	0.274
CLV_PCSK_SKI1_1	162	166	PF00082	0.240
CLV_PCSK_SKI1_1	192	196	PF00082	0.336
DEG_APCC_DBOX_1	95	103	PF00400	0.498
DEG_Nend_UBRbox_2	1	3	PF02207	0.626
DOC_MAPK_gen_1	160	166	PF00069	0.532
DOC_MAPK_gen_1	27	35	PF00069	0.395
DOC_MAPK_gen_1	95	102	PF00069	0.536
DOC_PP1_RVXF_1	160	167	PF00149	0.415
DOC_SPAK_OSR1_1	110	114	PF12202	0.471
DOC_USP7_MATH_1	129	133	PF00917	0.541
DOC_USP7_MATH_1	142	146	PF00917	0.475
DOC_USP7_UBL2_3	192	196	PF12436	0.522
DOC_USP7_UBL2_3	58	62	PF12436	0.538
LIG_14-3-3_CanoR_1	160	165	PF00244	0.512
LIG_14-3-3_CanoR_1	209	213	PF00244	0.465
LIG_14-3-3_CanoR_1	43	52	PF00244	0.539
LIG_14-3-3_CanoR_1	8	17	PF00244	0.420
LIG_APCC_ABBA_1	186	191	PF00400	0.532
LIG_BRCT_BRCA1_1	162	166	PF00533	0.508
LIG_FHA_1	170	176	PF00498	0.461
LIG_FHA_1	28	34	PF00498	0.425
LIG_FHA_1	76	82	PF00498	0.694
LIG_FHA_2	10	16	PF00498	0.435
LIG_FHA_2	48	54	PF00498	0.559
LIG_LIR_Gen_1	11	21	PF02991	0.425
LIG_LIR_Gen_1	163	174	PF02991	0.415
LIG_LIR_Nem_3	109	114	PF02991	0.451
LIG_LIR_Nem_3	11	17	PF02991	0.425
LIG_SH2_STAP1	171	175	PF00017	0.500
LIG_SH2_STAT3	52	55	PF00017	0.555
LIG_SH2_STAT5	122	125	PF00017	0.475
LIG_SH2_STAT5	171	174	PF00017	0.522
LIG_SH3_3	173	179	PF00018	0.555
LIG_SH3_3	221	227	PF00018	0.500
LIG_SH3_5	118	122	PF00018	0.536
LIG_SUMO_SIM_anti_2	32	37	PF11976	0.445
LIG_UBA3_1	99	106	PF00899	0.509
MOD_CK1_1	211	217	PF00069	0.453
MOD_CK2_1	142	148	PF00069	0.511
MOD_CK2_1	81	87	PF00069	0.550
MOD_CK2_1	9	15	PF00069	0.437
MOD_GSK3_1	124	131	PF00069	0.476
MOD_GSK3_1	149	156	PF00069	0.506
MOD_GSK3_1	165	172	PF00069	0.414
MOD_N-GLC_2	46	48	PF02516	0.541
MOD_PK_1	160	166	PF00069	0.513
MOD_PK_1	208	214	PF00069	0.489
MOD_PKA_1	160	166	PF00069	0.527
MOD_PKA_1	208	214	PF00069	0.500
MOD_PKA_2	160	166	PF00069	0.551
MOD_PKA_2	208	214	PF00069	0.522
MOD_PKA_2	9	15	PF00069	0.423
MOD_Plk_4	149	155	PF00069	0.446
MOD_Plk_4	165	171	PF00069	0.460
MOD_SUMO_for_1	61	64	PF00179	0.614
TRG_DiLeu_BaEn_3	75	81	PF01217	0.606
TRG_ER_diArg_1	160	162	PF00400	0.527
TRG_ER_diArg_1	94	97	PF00400	0.461
TRG_Pf-PMV_PEXEL_1	97	101	PF00026	0.263

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1II20	Leptomonas seymouri	75%	100%
A0A0S4J2X1	Bodo saltans	51%	95%
A0A1X0NJ53	Trypanosomatidae	59%	99%
A0A3R7KUG1	Trypanosoma rangeli	26%	98%
A0A3R7KZ12	Trypanosoma rangeli	60%	92%
A0A3S7WY28	Leishmania donovani	100%	100%
A4HD74	Leishmania braziliensis	81%	100%
D0A6Y6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	64%	99%
E9AWK6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
P20942	Rattus norvegicus	26%	98%
Q4QAW4	Leishmania major	93%	100%
Q71A38	Dictyostelium discoideum	26%	100%
Q9QW08	Mus musculus	26%	99%
V5BAV9	Trypanosoma cruzi	59%	99%