Glycosomal membrane like protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

glycosomal membrane like protein

Species:

Leishmania infantum

UniProt:

E9AH26_LEIIN

TriTrypDb:

LINF_240006200

Length:

220

Annotations

Annotations by Jardim et al.

Glycosome membrane, Peroxin 11 Glycosomal membrane like

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

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Expansion

Sequence features

E9AH26

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AH26

Function

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Biological processes
Term	Name	Level	Count
GO:0006996	organelle organization	4	11
GO:0009987	cellular process	1	11
GO:0016043	cellular component organization	3	11
GO:0016559	peroxisome fission	6	11
GO:0048285	organelle fission	5	11
GO:0071840	cellular component organization or biogenesis	2	11

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Could not find GO molecular_function term for this entry.

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	93	97	PF00656	0.388
CLV_PCSK_KEX2_1	146	148	PF00082	0.363
CLV_PCSK_KEX2_1	72	74	PF00082	0.338
CLV_PCSK_PC1ET2_1	146	148	PF00082	0.397
CLV_PCSK_PC1ET2_1	72	74	PF00082	0.337
CLV_PCSK_SKI1_1	120	124	PF00082	0.574
CLV_PCSK_SKI1_1	19	23	PF00082	0.292
CLV_PCSK_SKI1_1	78	82	PF00082	0.280
CLV_PCSK_SKI1_1	85	89	PF00082	0.308
DEG_APCC_DBOX_1	77	85	PF00400	0.520

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIQ6	Leptomonas seymouri	74%	100%
A0A1X0NJI5	Trypanosomatidae	33%	100%
A0A1X0NR15	Trypanosomatidae	31%	100%
A0A3Q8IB71	Leishmania donovani	100%	100%
A0A422P470	Trypanosoma rangeli	31%	100%
A4HD72	Leishmania braziliensis	86%	100%
A4HGT0	Leishmania braziliensis	25%	100%
D0A924	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	100%
E9AWK4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
Q4QAW6	Leishmania major	95%	100%

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