LeishMANIAdb
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Ankyrin/TPR repeat protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Ankyrin/TPR repeat protein
Gene product:
ankyrin/TPR repeat protein
Species:
Leishmania infantum
UniProt:
E9AH25_LEIIN
TriTrypDb:
LINF_240006100
Length:
394

Annotations

Annotations by Jardim et al.

Structural Proteins, Ankyrin/TPR repeat

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) yes yes: 3
Silverman et al. no yes: 0
Pissara et al. no yes: 8
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 7
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AH25
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AH25

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 220 224 PF00656 0.269
CLV_C14_Caspase3-7 73 77 PF00656 0.483
CLV_NRD_NRD_1 349 351 PF00675 0.392
CLV_PCSK_KEX2_1 272 274 PF00082 0.457
CLV_PCSK_PC1ET2_1 272 274 PF00082 0.477
CLV_PCSK_SKI1_1 28 32 PF00082 0.514
CLV_PCSK_SKI1_1 295 299 PF00082 0.402
CLV_PCSK_SKI1_1 346 350 PF00082 0.399
CLV_PCSK_SKI1_1 351 355 PF00082 0.365
CLV_PCSK_SKI1_1 390 394 PF00082 0.492
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I340 Leptomonas seymouri 84% 100%
A0A0S4ILI7 Bodo saltans 23% 100%
A0A0S4J2H9 Bodo saltans 28% 69%
A0A0S4J875 Bodo saltans 23% 89%
A0A0S4JCJ8 Bodo saltans 26% 87%
A0A1X0NIN0 Trypanosomatidae 65% 100%
A0A3Q8ICQ2 Leishmania donovani 99% 100%
A0A3R7N419 Trypanosoma rangeli 62% 100%
A4HD71 Leishmania braziliensis 87% 100%
A6NHY2 Homo sapiens 23% 75%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS