LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
E9AH16_LEIIN
TriTrypDb:
LINF_230026100
Length:
965

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AH16
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AH16

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 147 151 PF00656 0.550
CLV_C14_Caspase3-7 665 669 PF00656 0.336
CLV_MEL_PAP_1 890 896 PF00089 0.424
CLV_NRD_NRD_1 756 758 PF00675 0.403
CLV_NRD_NRD_1 792 794 PF00675 0.568
CLV_NRD_NRD_1 796 798 PF00675 0.568
CLV_NRD_NRD_1 877 879 PF00675 0.477
CLV_PCSK_KEX2_1 204 206 PF00082 0.544
CLV_PCSK_KEX2_1 756 758 PF00082 0.403
CLV_PCSK_KEX2_1 792 794 PF00082 0.569
CLV_PCSK_KEX2_1 796 798 PF00082 0.567
CLV_PCSK_PC1ET2_1 204 206 PF00082 0.427
CLV_PCSK_PC7_1 792 798 PF00082 0.542
CLV_PCSK_SKI1_1 100 104 PF00082 0.453
CLV_PCSK_SKI1_1 232 236 PF00082 0.436
CLV_PCSK_SKI1_1 265 269 PF00082 0.423
CLV_PCSK_SKI1_1 328 332 PF00082 0.634
CLV_PCSK_SKI1_1 616 620 PF00082 0.426
CLV_PCSK_SKI1_1 862 866 PF00082 0.455
DEG_APCC_DBOX_1 235 243 PF00400 0.325
DEG_APCC_DBOX_1 327 335 PF00400 0.407
DEG_APCC_DBOX_1 656 664 PF00400 0.355
DEG_SCF_FBW7_1 28 34 PF00400 0.481
DEG_SCF_FBW7_1 294 301 PF00400 0.501
DEG_SPOP_SBC_1 144 148 PF00917 0.446
DEG_SPOP_SBC_1 31 35 PF00917 0.490
DEG_SPOP_SBC_1 914 918 PF00917 0.470
DOC_CKS1_1 261 266 PF01111 0.404
DOC_CKS1_1 28 33 PF01111 0.530
DOC_CKS1_1 315 320 PF01111 0.706
DOC_CKS1_1 70 75 PF01111 0.529
DOC_CYCLIN_RxL_1 262 270 PF00134 0.470
DOC_MAPK_gen_1 204 211 PF00069 0.511
DOC_MAPK_gen_1 641 650 PF00069 0.483
DOC_MAPK_MEF2A_6 114 123 PF00069 0.516
DOC_PP2B_LxvP_1 605 608 PF13499 0.488
DOC_PP4_FxxP_1 8 11 PF00568 0.496
DOC_USP7_MATH_1 143 147 PF00917 0.481
DOC_USP7_MATH_1 298 302 PF00917 0.574
DOC_USP7_MATH_1 536 540 PF00917 0.656
DOC_USP7_MATH_1 555 559 PF00917 0.245
DOC_USP7_MATH_1 696 700 PF00917 0.404
DOC_USP7_MATH_1 889 893 PF00917 0.459
DOC_USP7_MATH_1 915 919 PF00917 0.410
DOC_USP7_UBL2_3 616 620 PF12436 0.451
DOC_USP7_UBL2_3 691 695 PF12436 0.292
DOC_WW_Pin1_4 260 265 PF00397 0.308
DOC_WW_Pin1_4 27 32 PF00397 0.512
DOC_WW_Pin1_4 294 299 PF00397 0.612
DOC_WW_Pin1_4 314 319 PF00397 0.674
DOC_WW_Pin1_4 347 352 PF00397 0.572
DOC_WW_Pin1_4 378 383 PF00397 0.516
DOC_WW_Pin1_4 416 421 PF00397 0.482
DOC_WW_Pin1_4 423 428 PF00397 0.491
DOC_WW_Pin1_4 433 438 PF00397 0.365
DOC_WW_Pin1_4 69 74 PF00397 0.490
DOC_WW_Pin1_4 732 737 PF00397 0.579
DOC_WW_Pin1_4 924 929 PF00397 0.538
LIG_14-3-3_CanoR_1 114 121 PF00244 0.543
LIG_14-3-3_CanoR_1 236 242 PF00244 0.324
LIG_14-3-3_CanoR_1 337 344 PF00244 0.452
LIG_14-3-3_CanoR_1 347 351 PF00244 0.337
LIG_14-3-3_CanoR_1 371 379 PF00244 0.483
LIG_14-3-3_CanoR_1 415 419 PF00244 0.491
LIG_14-3-3_CanoR_1 431 437 PF00244 0.354
LIG_14-3-3_CanoR_1 636 641 PF00244 0.385
LIG_14-3-3_CanoR_1 657 661 PF00244 0.427
LIG_14-3-3_CanoR_1 761 765 PF00244 0.389
LIG_14-3-3_CanoR_1 807 816 PF00244 0.437
LIG_14-3-3_CanoR_1 937 942 PF00244 0.409
LIG_14-3-3_CanoR_1 951 955 PF00244 0.407
LIG_Actin_WH2_2 220 238 PF00022 0.324
LIG_BIR_III_2 461 465 PF00653 0.460
LIG_BIR_III_2 600 604 PF00653 0.596
LIG_BRCT_BRCA1_1 220 224 PF00533 0.388
LIG_BRCT_BRCA1_1 373 377 PF00533 0.529
LIG_BRCT_BRCA1_1 4 8 PF00533 0.547
LIG_Clathr_ClatBox_1 701 705 PF01394 0.372
LIG_deltaCOP1_diTrp_1 621 627 PF00928 0.602
LIG_deltaCOP1_diTrp_1 631 640 PF00928 0.445
LIG_DLG_GKlike_1 937 945 PF00625 0.451
LIG_eIF4E_1 261 267 PF01652 0.446
LIG_eIF4E_1 941 947 PF01652 0.433
LIG_FHA_1 133 139 PF00498 0.481
LIG_FHA_1 178 184 PF00498 0.510
LIG_FHA_1 195 201 PF00498 0.371
LIG_FHA_1 261 267 PF00498 0.446
LIG_FHA_1 276 282 PF00498 0.363
LIG_FHA_1 295 301 PF00498 0.381
LIG_FHA_1 315 321 PF00498 0.733
LIG_FHA_1 441 447 PF00498 0.355
LIG_FHA_1 485 491 PF00498 0.417
LIG_FHA_1 530 536 PF00498 0.493
LIG_FHA_1 597 603 PF00498 0.564
LIG_FHA_1 76 82 PF00498 0.394
LIG_FHA_1 91 97 PF00498 0.407
LIG_FHA_1 915 921 PF00498 0.468
LIG_FHA_2 354 360 PF00498 0.496
LIG_FHA_2 621 627 PF00498 0.595
LIG_FHA_2 70 76 PF00498 0.463
LIG_FHA_2 836 842 PF00498 0.577
LIG_FHA_2 863 869 PF00498 0.524
LIG_FHA_2 925 931 PF00498 0.437
LIG_Integrin_RGD_1 956 958 PF01839 0.529
LIG_LIR_Apic_2 260 264 PF02991 0.436
LIG_LIR_Apic_2 381 387 PF02991 0.523
LIG_LIR_Apic_2 5 11 PF02991 0.522
LIG_LIR_Gen_1 240 248 PF02991 0.435
LIG_LIR_Gen_1 362 372 PF02991 0.483
LIG_LIR_Gen_1 468 477 PF02991 0.409
LIG_LIR_Gen_1 77 87 PF02991 0.416
LIG_LIR_Gen_1 841 849 PF02991 0.408
LIG_LIR_LC3C_4 906 911 PF02991 0.501
LIG_LIR_Nem_3 172 176 PF02991 0.484
LIG_LIR_Nem_3 190 195 PF02991 0.211
LIG_LIR_Nem_3 221 227 PF02991 0.393
LIG_LIR_Nem_3 240 244 PF02991 0.412
LIG_LIR_Nem_3 362 367 PF02991 0.500
LIG_LIR_Nem_3 426 432 PF02991 0.543
LIG_LIR_Nem_3 468 473 PF02991 0.403
LIG_LIR_Nem_3 715 721 PF02991 0.382
LIG_LIR_Nem_3 77 83 PF02991 0.423
LIG_LIR_Nem_3 799 804 PF02991 0.484
LIG_MYND_1 383 387 PF01753 0.317
LIG_PTB_Apo_2 321 328 PF02174 0.580
LIG_PTB_Apo_2 544 551 PF02174 0.411
LIG_PTB_Phospho_1 321 327 PF10480 0.577
LIG_Rb_LxCxE_1 674 690 PF01857 0.362
LIG_SH2_CRK 173 177 PF00017 0.430
LIG_SH2_CRK 261 265 PF00017 0.317
LIG_SH2_CRK 718 722 PF00017 0.380
LIG_SH2_GRB2like 322 325 PF00017 0.586
LIG_SH2_PTP2 80 83 PF00017 0.486
LIG_SH2_SRC 322 325 PF00017 0.586
LIG_SH2_STAP1 934 938 PF00017 0.463
LIG_SH2_STAP1 941 945 PF00017 0.359
LIG_SH2_STAT3 855 858 PF00017 0.475
LIG_SH2_STAT5 128 131 PF00017 0.412
LIG_SH2_STAT5 162 165 PF00017 0.546
LIG_SH2_STAT5 412 415 PF00017 0.560
LIG_SH2_STAT5 527 530 PF00017 0.393
LIG_SH2_STAT5 614 617 PF00017 0.436
LIG_SH2_STAT5 709 712 PF00017 0.464
LIG_SH2_STAT5 739 742 PF00017 0.503
LIG_SH2_STAT5 80 83 PF00017 0.427
LIG_SH2_STAT5 817 820 PF00017 0.351
LIG_SH2_STAT5 842 845 PF00017 0.468
LIG_SH3_1 424 430 PF00018 0.410
LIG_SH3_3 106 112 PF00018 0.477
LIG_SH3_3 25 31 PF00018 0.534
LIG_SH3_3 312 318 PF00018 0.671
LIG_SH3_3 376 382 PF00018 0.487
LIG_SH3_3 417 423 PF00018 0.493
LIG_SH3_3 424 430 PF00018 0.517
LIG_SH3_3 485 491 PF00018 0.488
LIG_SH3_3 532 538 PF00018 0.605
LIG_SH3_3 569 575 PF00018 0.671
LIG_SUMO_SIM_par_1 301 307 PF11976 0.689
LIG_SUMO_SIM_par_1 486 493 PF11976 0.433
LIG_SUMO_SIM_par_1 662 668 PF11976 0.354
LIG_TYR_ITIM 707 712 PF00017 0.371
LIG_TYR_ITSM 188 195 PF00017 0.378
LIG_TYR_ITSM 76 83 PF00017 0.451
LIG_WRC_WIRS_1 241 246 PF05994 0.462
LIG_WRC_WIRS_1 714 719 PF05994 0.436
MOD_CDK_SPK_2 260 265 PF00069 0.308
MOD_CK1_1 243 249 PF00069 0.456
MOD_CK1_1 388 394 PF00069 0.535
MOD_CK1_1 476 482 PF00069 0.515
MOD_CK1_1 649 655 PF00069 0.498
MOD_CK1_1 713 719 PF00069 0.456
MOD_CK1_1 727 733 PF00069 0.453
MOD_CK1_1 776 782 PF00069 0.428
MOD_CK1_1 811 817 PF00069 0.530
MOD_CK2_1 32 38 PF00069 0.490
MOD_CK2_1 347 353 PF00069 0.450
MOD_CK2_1 555 561 PF00069 0.337
MOD_CK2_1 625 631 PF00069 0.634
MOD_CK2_1 69 75 PF00069 0.435
MOD_CK2_1 835 841 PF00069 0.545
MOD_CK2_1 924 930 PF00069 0.448
MOD_CK2_1 937 943 PF00069 0.314
MOD_Cter_Amidation 202 205 PF01082 0.580
MOD_Cter_Amidation 794 797 PF01082 0.487
MOD_GlcNHglycan 115 118 PF01048 0.587
MOD_GlcNHglycan 129 132 PF01048 0.375
MOD_GlcNHglycan 141 144 PF01048 0.463
MOD_GlcNHglycan 177 180 PF01048 0.547
MOD_GlcNHglycan 281 284 PF01048 0.400
MOD_GlcNHglycan 310 313 PF01048 0.625
MOD_GlcNHglycan 467 470 PF01048 0.405
MOD_GlcNHglycan 504 507 PF01048 0.519
MOD_GlcNHglycan 538 541 PF01048 0.729
MOD_GlcNHglycan 557 560 PF01048 0.415
MOD_GlcNHglycan 565 568 PF01048 0.561
MOD_GlcNHglycan 576 579 PF01048 0.688
MOD_GlcNHglycan 590 593 PF01048 0.490
MOD_GlcNHglycan 651 654 PF01048 0.491
MOD_GlcNHglycan 730 733 PF01048 0.653
MOD_GlcNHglycan 810 813 PF01048 0.503
MOD_GlcNHglycan 97 100 PF01048 0.421
MOD_GSK3_1 139 146 PF00069 0.490
MOD_GSK3_1 156 163 PF00069 0.524
MOD_GSK3_1 195 202 PF00069 0.523
MOD_GSK3_1 240 247 PF00069 0.401
MOD_GSK3_1 27 34 PF00069 0.508
MOD_GSK3_1 275 282 PF00069 0.410
MOD_GSK3_1 294 301 PF00069 0.565
MOD_GSK3_1 304 311 PF00069 0.625
MOD_GSK3_1 383 390 PF00069 0.487
MOD_GSK3_1 414 421 PF00069 0.496
MOD_GSK3_1 472 479 PF00069 0.434
MOD_GSK3_1 502 509 PF00069 0.436
MOD_GSK3_1 632 639 PF00069 0.456
MOD_GSK3_1 652 659 PF00069 0.550
MOD_GSK3_1 724 731 PF00069 0.533
MOD_GSK3_1 773 780 PF00069 0.387
MOD_GSK3_1 796 803 PF00069 0.536
MOD_GSK3_1 807 814 PF00069 0.518
MOD_LATS_1 794 800 PF00433 0.506
MOD_N-GLC_1 465 470 PF02516 0.397
MOD_N-GLC_1 48 53 PF02516 0.457
MOD_N-GLC_1 882 887 PF02516 0.454
MOD_NEK2_1 103 108 PF00069 0.447
MOD_NEK2_1 127 132 PF00069 0.321
MOD_NEK2_1 175 180 PF00069 0.415
MOD_NEK2_1 194 199 PF00069 0.353
MOD_NEK2_1 244 249 PF00069 0.427
MOD_NEK2_1 252 257 PF00069 0.399
MOD_NEK2_1 275 280 PF00069 0.440
MOD_NEK2_1 286 291 PF00069 0.360
MOD_NEK2_1 346 351 PF00069 0.520
MOD_NEK2_1 440 445 PF00069 0.442
MOD_NEK2_1 465 470 PF00069 0.400
MOD_NEK2_1 472 477 PF00069 0.368
MOD_NEK2_1 529 534 PF00069 0.438
MOD_NEK2_1 549 554 PF00069 0.458
MOD_NEK2_1 582 587 PF00069 0.623
MOD_NEK2_1 632 637 PF00069 0.411
MOD_NEK2_1 712 717 PF00069 0.543
MOD_NEK2_1 740 745 PF00069 0.464
MOD_NEK2_1 89 94 PF00069 0.572
MOD_NEK2_1 950 955 PF00069 0.417
MOD_NEK2_2 48 53 PF00069 0.505
MOD_PIKK_1 286 292 PF00454 0.488
MOD_PIKK_1 304 310 PF00454 0.463
MOD_PIKK_1 371 377 PF00454 0.369
MOD_PKA_1 796 802 PF00069 0.524
MOD_PKA_2 113 119 PF00069 0.536
MOD_PKA_2 144 150 PF00069 0.530
MOD_PKA_2 308 314 PF00069 0.680
MOD_PKA_2 336 342 PF00069 0.565
MOD_PKA_2 346 352 PF00069 0.374
MOD_PKA_2 414 420 PF00069 0.461
MOD_PKA_2 588 594 PF00069 0.601
MOD_PKA_2 59 65 PF00069 0.436
MOD_PKA_2 656 662 PF00069 0.411
MOD_PKA_2 740 746 PF00069 0.531
MOD_PKA_2 760 766 PF00069 0.386
MOD_PKA_2 796 802 PF00069 0.476
MOD_PKA_2 950 956 PF00069 0.484
MOD_PKB_1 634 642 PF00069 0.397
MOD_PKB_1 937 945 PF00069 0.451
MOD_Plk_1 465 471 PF00069 0.409
MOD_Plk_1 560 566 PF00069 0.374
MOD_Plk_1 710 716 PF00069 0.439
MOD_Plk_1 840 846 PF00069 0.498
MOD_Plk_1 882 888 PF00069 0.608
MOD_Plk_2-3 353 359 PF00069 0.522
MOD_Plk_4 210 216 PF00069 0.541
MOD_Plk_4 218 224 PF00069 0.327
MOD_Plk_4 237 243 PF00069 0.470
MOD_Plk_4 252 258 PF00069 0.439
MOD_Plk_4 484 490 PF00069 0.496
MOD_Plk_4 646 652 PF00069 0.448
MOD_Plk_4 656 662 PF00069 0.298
MOD_Plk_4 697 703 PF00069 0.500
MOD_Plk_4 713 719 PF00069 0.399
MOD_Plk_4 740 746 PF00069 0.455
MOD_Plk_4 75 81 PF00069 0.468
MOD_Plk_4 781 787 PF00069 0.483
MOD_Plk_4 9 15 PF00069 0.486
MOD_Plk_4 950 956 PF00069 0.379
MOD_ProDKin_1 260 266 PF00069 0.321
MOD_ProDKin_1 27 33 PF00069 0.526
MOD_ProDKin_1 294 300 PF00069 0.612
MOD_ProDKin_1 314 320 PF00069 0.675
MOD_ProDKin_1 347 353 PF00069 0.572
MOD_ProDKin_1 378 384 PF00069 0.508
MOD_ProDKin_1 416 422 PF00069 0.487
MOD_ProDKin_1 423 429 PF00069 0.491
MOD_ProDKin_1 433 439 PF00069 0.360
MOD_ProDKin_1 69 75 PF00069 0.495
MOD_ProDKin_1 732 738 PF00069 0.572
MOD_ProDKin_1 924 930 PF00069 0.536
MOD_SUMO_for_1 725 728 PF00179 0.524
MOD_SUMO_rev_2 150 160 PF00179 0.428
TRG_DiLeu_BaEn_1 270 275 PF01217 0.579
TRG_DiLeu_BaEn_1 905 910 PF01217 0.505
TRG_DiLeu_BaLyEn_6 262 267 PF01217 0.515
TRG_DiLeu_BaLyEn_6 289 294 PF01217 0.493
TRG_DiLeu_BaLyEn_6 396 401 PF01217 0.448
TRG_DiLeu_LyEn_5 270 275 PF01217 0.540
TRG_ENDOCYTIC_2 173 176 PF00928 0.534
TRG_ENDOCYTIC_2 192 195 PF00928 0.195
TRG_ENDOCYTIC_2 327 330 PF00928 0.552
TRG_ENDOCYTIC_2 709 712 PF00928 0.395
TRG_ENDOCYTIC_2 718 721 PF00928 0.313
TRG_ENDOCYTIC_2 80 83 PF00928 0.466
TRG_ENDOCYTIC_2 842 845 PF00928 0.422
TRG_ER_diArg_1 633 636 PF00400 0.540
TRG_ER_diArg_1 640 643 PF00400 0.470
TRG_ER_diArg_1 755 757 PF00400 0.398
TRG_NES_CRM1_1 284 295 PF08389 0.470
TRG_Pf-PMV_PEXEL_1 265 270 PF00026 0.550
TRG_Pf-PMV_PEXEL_1 371 375 PF00026 0.401

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HXF5 Leptomonas seymouri 45% 99%
A0A1X0NWP8 Trypanosomatidae 25% 100%
A0A3Q8IEQ1 Leishmania donovani 99% 100%
A0A422NJD5 Trypanosoma rangeli 25% 100%
A4HD38 Leishmania braziliensis 78% 100%
C9ZNR7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 26% 98%
E9AWI6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%
Q4QAY4 Leishmania major 92% 100%
V5B6R7 Trypanosoma cruzi 27% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS