IQ_calmodulin-binding_motif_containing_protein_-_putative

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

IQ calmodulin-binding motif containing protein - putative

Species:

Leishmania infantum

UniProt:

E9AGX9_LEIIN

TriTrypDb:

LINF_210019100

Length:

1769

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AGX9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGX9

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	1
GO:0005515	protein binding	2	1
GO:0005516	calmodulin binding	3	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	183	187	PF00656	0.755
CLV_C14_Caspase3-7	414	418	PF00656	0.496
CLV_MEL_PAP_1	1185	1191	PF00089	0.509
CLV_NRD_NRD_1	1004	1006	PF00675	0.429
CLV_NRD_NRD_1	106	108	PF00675	0.589
CLV_NRD_NRD_1	1069	1071	PF00675	0.500
CLV_NRD_NRD_1	1097	1099	PF00675	0.534
CLV_NRD_NRD_1	1173	1175	PF00675	0.549
CLV_NRD_NRD_1	1196	1198	PF00675	0.454
CLV_NRD_NRD_1	1203	1205	PF00675	0.467

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIB0	Leptomonas seymouri	54%	98%
A0A0S4JFY0	Bodo saltans	31%	100%
A0A3Q8IDZ3	Leishmania donovani	100%	100%
A0A3R7KW01	Trypanosoma rangeli	35%	100%
A4HBW9	Leishmania braziliensis	74%	98%
D0A184	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	100%
E9AV95	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
Q4QC85	Leishmania major	91%	99%
V5BE65	Trypanosoma cruzi	35%	100%

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