LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
E9AGW8_LEIIN
TriTrypDb:
LINF_210017600
Length:
2048

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AGW8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGW8

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 1262 1266 PF00656 0.769
CLV_C14_Caspase3-7 1303 1307 PF00656 0.736
CLV_C14_Caspase3-7 1327 1331 PF00656 0.732
CLV_C14_Caspase3-7 1665 1669 PF00656 0.748
CLV_NRD_NRD_1 1078 1080 PF00675 0.717
CLV_NRD_NRD_1 1337 1339 PF00675 0.856
CLV_NRD_NRD_1 138 140 PF00675 0.622
CLV_NRD_NRD_1 1404 1406 PF00675 0.807
CLV_NRD_NRD_1 1892 1894 PF00675 0.786
CLV_NRD_NRD_1 1979 1981 PF00675 0.735
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3S7WWJ4 Leishmania donovani 100% 100%
A4HBW0 Leishmania braziliensis 61% 99%
E9AV84 Leishmania mexicana (strain MHOM/GT/2001/U1103) 79% 99%
Q4QC96 Leishmania major 85% 99%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS