Uncharacterized protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AGW7_LEIIN

TriTrypDb:

LINF_210017500

Length:

142

Annotations

LeishMANIAdb annotations

A single-pass helical protein with a potential mitochondrial transit signal. Localization: Mitochondrial (by homology)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Show entries

Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	1
GO:0016020	membrane	2	6
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	6

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Expansion

Sequence features

E9AGW7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGW7

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	58	60	PF00675	0.371
CLV_NRD_NRD_1	73	75	PF00675	0.326
CLV_PCSK_KEX2_1	58	60	PF00082	0.388
CLV_PCSK_KEX2_1	73	75	PF00082	0.324
CLV_PCSK_SKI1_1	131	135	PF00082	0.370
CLV_PCSK_SKI1_1	60	64	PF00082	0.345
CLV_PCSK_SKI1_1	74	78	PF00082	0.368
DEG_APCC_DBOX_1	73	81	PF00400	0.641
DOC_MAPK_gen_1	122	130	PF00069	0.612
DOC_MAPK_gen_1	48	57	PF00069	0.579

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3R0	Leptomonas seymouri	75%	100%
A0A1X0NYD4	Trypanosomatidae	64%	100%
A0A3Q8IBW9	Leishmania donovani	100%	100%
A4HBV9	Leishmania braziliensis	91%	100%
D0A199	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	61%	96%
E9AV83	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
Q4QC97	Leishmania major	97%	100%

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