Mitochondrial RNA binding complex 1 subunit

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AGU1_LEIIN

TriTrypDb:

LINF_200014900

Length:

508

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AGU1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGU1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	188	192	PF00656	0.576
CLV_NRD_NRD_1	24	26	PF00675	0.539
CLV_NRD_NRD_1	335	337	PF00675	0.571
CLV_NRD_NRD_1	348	350	PF00675	0.363
CLV_NRD_NRD_1	418	420	PF00675	0.658
CLV_NRD_NRD_1	46	48	PF00675	0.712
CLV_NRD_NRD_1	65	67	PF00675	0.470
CLV_PCSK_KEX2_1	140	142	PF00082	0.429
CLV_PCSK_KEX2_1	24	26	PF00082	0.539
CLV_PCSK_KEX2_1	294	296	PF00082	0.721
CLV_PCSK_KEX2_1	303	305	PF00082	0.576
CLV_PCSK_KEX2_1	335	337	PF00082	0.571
CLV_PCSK_KEX2_1	348	350	PF00082	0.363
CLV_PCSK_KEX2_1	46	48	PF00082	0.582
CLV_PCSK_KEX2_1	65	67	PF00082	0.430
CLV_PCSK_PC1ET2_1	140	142	PF00082	0.429
CLV_PCSK_PC1ET2_1	294	296	PF00082	0.575
CLV_PCSK_PC1ET2_1	303	305	PF00082	0.470
CLV_PCSK_PC7_1	331	337	PF00082	0.548
CLV_PCSK_SKI1_1	24	28	PF00082	0.604
CLV_PCSK_SKI1_1	303	307	PF00082	0.585
CLV_PCSK_SKI1_1	331	335	PF00082	0.530
DEG_APCC_DBOX_1	330	338	PF00400	0.548
DEG_APCC_DBOX_1	441	449	PF00400	0.515
DEG_Nend_UBRbox_1	1	4	PF02207	0.567
DEG_SPOP_SBC_1	277	281	PF00917	0.539
DEG_SPOP_SBC_1	469	473	PF00917	0.606
DEG_SPOP_SBC_1	85	89	PF00917	0.484
DOC_ANK_TNKS_1	140	147	PF00023	0.464
DOC_MAPK_gen_1	303	311	PF00069	0.563
DOC_MAPK_gen_1	439	448	PF00069	0.491
DOC_MAPK_MEF2A_6	304	313	PF00069	0.528
DOC_MAPK_MEF2A_6	364	372	PF00069	0.496
DOC_MAPK_MEF2A_6	442	450	PF00069	0.490
DOC_PP2B_LxvP_1	274	277	PF13499	0.603
DOC_PP2B_LxvP_1	288	291	PF13499	0.457
DOC_PP4_FxxP_1	142	145	PF00568	0.455
DOC_USP7_MATH_1	179	183	PF00917	0.436
DOC_USP7_MATH_1	278	282	PF00917	0.680
DOC_USP7_MATH_1	467	471	PF00917	0.618
DOC_USP7_MATH_1	53	57	PF00917	0.727
DOC_USP7_MATH_1	79	83	PF00917	0.503
DOC_USP7_MATH_1	84	88	PF00917	0.478
DOC_WW_Pin1_4	19	24	PF00397	0.530
DOC_WW_Pin1_4	397	402	PF00397	0.521
DOC_WW_Pin1_4	412	417	PF00397	0.620
DOC_WW_Pin1_4	465	470	PF00397	0.636
LIG_14-3-3_CanoR_1	304	309	PF00244	0.547
LIG_14-3-3_CanoR_1	348	352	PF00244	0.542
LIG_14-3-3_CanoR_1	419	427	PF00244	0.806
LIG_14-3-3_CanoR_1	442	446	PF00244	0.517
LIG_14-3-3_CterR_2	505	508	PF00244	0.560
LIG_Actin_WH2_2	322	337	PF00022	0.547
LIG_APCC_ABBA_1	252	257	PF00400	0.476
LIG_BRCT_BRCA1_1	119	123	PF00533	0.448
LIG_BRCT_BRCA1_1	2	6	PF00533	0.494
LIG_BRCT_BRCA1_1	460	464	PF00533	0.712
LIG_CaM_IQ_9	370	385	PF13499	0.493
LIG_DLG_GKlike_1	164	172	PF00625	0.492
LIG_FHA_1	122	128	PF00498	0.517
LIG_FHA_1	219	225	PF00498	0.609
LIG_FHA_1	304	310	PF00498	0.456
LIG_FHA_1	35	41	PF00498	0.471
LIG_FHA_1	352	358	PF00498	0.477
LIG_FHA_1	442	448	PF00498	0.502
LIG_FHA_1	476	482	PF00498	0.586
LIG_FHA_1	87	93	PF00498	0.515
LIG_FHA_2	198	204	PF00498	0.590
LIG_FHA_2	67	73	PF00498	0.474
LIG_LIR_Apic_2	56	62	PF02991	0.545
LIG_LIR_Gen_1	120	131	PF02991	0.397
LIG_LIR_Gen_1	307	316	PF02991	0.496
LIG_LIR_Gen_1	365	373	PF02991	0.609
LIG_LIR_Gen_1	45	55	PF02991	0.496
LIG_LIR_Nem_3	120	126	PF02991	0.424
LIG_LIR_Nem_3	3	9	PF02991	0.485
LIG_LIR_Nem_3	307	313	PF02991	0.496
LIG_LIR_Nem_3	365	369	PF02991	0.489
LIG_LIR_Nem_3	45	51	PF02991	0.490
LIG_LIR_Nem_3	492	496	PF02991	0.489
LIG_RPA_C_Fungi	42	54	PF08784	0.554
LIG_SH2_CRK	493	497	PF00017	0.482
LIG_SH2_CRK	59	63	PF00017	0.553
LIG_SH2_NCK_1	155	159	PF00017	0.469
LIG_SH2_NCK_1	59	63	PF00017	0.581
LIG_SH2_PTP2	310	313	PF00017	0.551
LIG_SH2_SRC	155	158	PF00017	0.461
LIG_SH2_STAP1	353	357	PF00017	0.532
LIG_SH2_STAT5	130	133	PF00017	0.378
LIG_SH2_STAT5	174	177	PF00017	0.439
LIG_SH2_STAT5	234	237	PF00017	0.329
LIG_SH2_STAT5	262	265	PF00017	0.436
LIG_SH2_STAT5	310	313	PF00017	0.500
LIG_SH2_STAT5	353	356	PF00017	0.425
LIG_SH2_STAT5	361	364	PF00017	0.431
LIG_SH2_STAT5	455	458	PF00017	0.619
LIG_SH3_3	1	7	PF00018	0.584
LIG_SH3_3	142	148	PF00018	0.475
LIG_SH3_3	354	360	PF00018	0.473
LIG_SH3_3	398	404	PF00018	0.524
LIG_SUMO_SIM_anti_2	221	226	PF11976	0.451
LIG_SUMO_SIM_anti_2	444	449	PF11976	0.496
LIG_SUMO_SIM_par_1	265	271	PF11976	0.508
LIG_SUMO_SIM_par_1	87	93	PF11976	0.514
LIG_TYR_ITIM	153	158	PF00017	0.464
LIG_TYR_ITIM	308	313	PF00017	0.548
LIG_WRC_WIRS_1	363	368	PF05994	0.497
MOD_CDC14_SPxK_1	22	25	PF00782	0.528
MOD_CDK_SPK_2	19	24	PF00069	0.577
MOD_CDK_SPK_2	397	402	PF00069	0.521
MOD_CDK_SPK_2	412	417	PF00069	0.514
MOD_CDK_SPxK_1	19	25	PF00069	0.520
MOD_CDK_SPxxK_3	412	419	PF00069	0.570
MOD_CK1_1	116	122	PF00069	0.571
MOD_CK1_1	182	188	PF00069	0.558
MOD_CK1_1	315	321	PF00069	0.618
MOD_CK1_1	32	38	PF00069	0.622
MOD_CK1_1	405	411	PF00069	0.627
MOD_CK1_1	412	418	PF00069	0.672
MOD_CK1_1	458	464	PF00069	0.541
MOD_CK1_1	465	471	PF00069	0.598
MOD_CK1_1	93	99	PF00069	0.512
MOD_CK2_1	119	125	PF00069	0.527
MOD_CK2_1	277	283	PF00069	0.545
MOD_CK2_1	66	72	PF00069	0.492
MOD_GlcNHglycan	148	151	PF01048	0.631
MOD_GlcNHglycan	159	162	PF01048	0.462
MOD_GlcNHglycan	185	188	PF01048	0.538
MOD_GlcNHglycan	208	211	PF01048	0.526
MOD_GlcNHglycan	27	30	PF01048	0.559
MOD_GlcNHglycan	280	283	PF01048	0.554
MOD_GlcNHglycan	314	317	PF01048	0.544
MOD_GlcNHglycan	408	411	PF01048	0.654
MOD_GlcNHglycan	428	431	PF01048	0.629
MOD_GlcNHglycan	464	467	PF01048	0.590
MOD_GlcNHglycan	496	499	PF01048	0.597
MOD_GlcNHglycan	55	58	PF01048	0.641
MOD_GlcNHglycan	82	85	PF01048	0.524
MOD_GlcNHglycan	92	95	PF01048	0.536
MOD_GSK3_1	113	120	PF00069	0.518
MOD_GSK3_1	15	22	PF00069	0.550
MOD_GSK3_1	164	171	PF00069	0.643
MOD_GSK3_1	179	186	PF00069	0.473
MOD_GSK3_1	214	221	PF00069	0.466
MOD_GSK3_1	25	32	PF00069	0.532
MOD_GSK3_1	347	354	PF00069	0.635
MOD_GSK3_1	402	409	PF00069	0.591
MOD_GSK3_1	458	465	PF00069	0.613
MOD_GSK3_1	467	474	PF00069	0.521
MOD_GSK3_1	80	87	PF00069	0.633
MOD_LATS_1	162	168	PF00433	0.496
MOD_N-GLC_1	318	323	PF02516	0.648
MOD_NEK2_1	168	173	PF00069	0.435
MOD_NEK2_1	180	185	PF00069	0.493
MOD_NEK2_1	204	209	PF00069	0.737
MOD_NEK2_1	218	223	PF00069	0.395
MOD_NEK2_1	347	352	PF00069	0.491
MOD_NEK2_1	42	47	PF00069	0.520
MOD_NEK2_1	8	13	PF00069	0.563
MOD_NEK2_1	90	95	PF00069	0.496
MOD_NEK2_2	256	261	PF00069	0.509
MOD_PIKK_1	110	116	PF00454	0.570
MOD_PIKK_1	228	234	PF00454	0.381
MOD_PIKK_1	471	477	PF00454	0.614
MOD_PK_1	304	310	PF00069	0.454
MOD_PK_1	402	408	PF00069	0.544
MOD_PKA_1	303	309	PF00069	0.560
MOD_PKA_1	494	500	PF00069	0.523
MOD_PKA_2	29	35	PF00069	0.525
MOD_PKA_2	303	309	PF00069	0.560
MOD_PKA_2	347	353	PF00069	0.474
MOD_PKA_2	441	447	PF00069	0.519
MOD_Plk_1	214	220	PF00069	0.472
MOD_Plk_4	304	310	PF00069	0.541
MOD_Plk_4	441	447	PF00069	0.654
MOD_Plk_4	93	99	PF00069	0.418
MOD_ProDKin_1	19	25	PF00069	0.535
MOD_ProDKin_1	397	403	PF00069	0.522
MOD_ProDKin_1	412	418	PF00069	0.618
MOD_ProDKin_1	465	471	PF00069	0.637
MOD_SUMO_for_1	293	296	PF00179	0.575
TRG_ENDOCYTIC_2	139	142	PF00928	0.489
TRG_ENDOCYTIC_2	155	158	PF00928	0.339
TRG_ENDOCYTIC_2	310	313	PF00928	0.500
TRG_ENDOCYTIC_2	493	496	PF00928	0.486
TRG_ER_diArg_1	23	25	PF00400	0.538
TRG_ER_diArg_1	334	336	PF00400	0.548
TRG_ER_diArg_1	347	349	PF00400	0.370
TRG_ER_diArg_1	416	419	PF00400	0.698
TRG_ER_diArg_1	46	48	PF00400	0.582
TRG_ER_diArg_1	504	507	PF00400	0.567
TRG_ER_diArg_1	65	67	PF00400	0.430

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P496	Leptomonas seymouri	42%	91%
A0A3S7WVY4	Leishmania donovani	100%	100%
E9AUN7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%
Q4QCU7	Leishmania major	85%	100%