LeishMANIAdb
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Syntaxin-binding protein 2

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Syntaxin-binding protein 2
Gene product:
Protein of unknown function (DUF2946), putative
Species:
Leishmania infantum
UniProt:
E9AGS8_LEIIN
TriTrypDb:
Length:
235

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Cellular components
Term Name Level Count
GO:0016020 membrane 2 2
GO:0110165 cellular anatomical entity 1 2

Expansion

Sequence features

E9AGS8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGS8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 225 229 PF00656 0.556
DEG_Nend_Nbox_1 1 3 PF02207 0.370
DOC_CYCLIN_yCln2_LP_2 18 24 PF00134 0.357
DOC_CYCLIN_yCln2_LP_2 3 9 PF00134 0.365
DOC_MAPK_gen_1 201 210 PF00069 0.554
DOC_MAPK_gen_1 211 220 PF00069 0.546
DOC_MAPK_HePTP_8 102 114 PF00069 0.199
DOC_MAPK_HePTP_8 140 152 PF00069 0.199
DOC_MAPK_HePTP_8 200 212 PF00069 0.413
DOC_MAPK_MEF2A_6 105 114 PF00069 0.400
DOC_MAPK_MEF2A_6 143 152 PF00069 0.400
DOC_MAPK_MEF2A_6 201 210 PF00069 0.554
DOC_MAPK_MEF2A_6 211 220 PF00069 0.546
DOC_PP1_RVXF_1 215 221 PF00149 0.546
DOC_PP1_RVXF_1 9 15 PF00149 0.360
DOC_USP7_MATH_1 227 231 PF00917 0.557
LIG_14-3-3_CanoR_1 4 14 PF00244 0.363
LIG_PDZ_Class_1 230 235 PF00595 0.558
LIG_Vh1_VBS_1 27 45 PF01044 0.199
MOD_GlcNHglycan 7 10 PF01048 0.562
MOD_NEK2_1 10 15 PF00069 0.359
MOD_NEK2_2 227 232 PF00069 0.558
MOD_PKA_2 10 16 PF00069 0.358
MOD_Plk_4 10 16 PF00069 0.358
TRG_ER_diArg_1 200 203 PF00400 0.429
TRG_ER_diArg_1 204 207 PF00400 0.549
TRG_ER_diArg_1 208 211 PF00400 0.546
TRG_ER_diArg_1 212 215 PF00400 0.545

Homologs

Protein Taxonomy Sequence identity Coverage
Q65169 ASFB7 27% 39%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS