LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
DnaJ domain containing protein - putative
Species:
Leishmania infantum
UniProt:
E9AGR0_LEIIN
TriTrypDb:
LINF_190005600
Length:
432

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 12
NetGPI no yes: 0, no: 12
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AGR0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGR0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 296 300 PF00656 0.630
CLV_NRD_NRD_1 104 106 PF00675 0.694
CLV_NRD_NRD_1 157 159 PF00675 0.545
CLV_NRD_NRD_1 179 181 PF00675 0.498
CLV_NRD_NRD_1 190 192 PF00675 0.476
CLV_NRD_NRD_1 214 216 PF00675 0.514
CLV_NRD_NRD_1 266 268 PF00675 0.536
CLV_NRD_NRD_1 302 304 PF00675 0.571
CLV_NRD_NRD_1 375 377 PF00675 0.565
CLV_NRD_NRD_1 388 390 PF00675 0.514
CLV_NRD_NRD_1 398 400 PF00675 0.487
CLV_NRD_NRD_1 69 71 PF00675 0.550
CLV_PCSK_FUR_1 214 218 PF00082 0.557
CLV_PCSK_KEX2_1 157 159 PF00082 0.572
CLV_PCSK_KEX2_1 178 180 PF00082 0.496
CLV_PCSK_KEX2_1 189 191 PF00082 0.476
CLV_PCSK_KEX2_1 214 216 PF00082 0.537
CLV_PCSK_KEX2_1 258 260 PF00082 0.550
CLV_PCSK_KEX2_1 265 267 PF00082 0.508
CLV_PCSK_KEX2_1 302 304 PF00082 0.599
CLV_PCSK_KEX2_1 336 338 PF00082 0.538
CLV_PCSK_KEX2_1 377 379 PF00082 0.584
CLV_PCSK_KEX2_1 387 389 PF00082 0.540
CLV_PCSK_KEX2_1 398 400 PF00082 0.486
CLV_PCSK_KEX2_1 59 61 PF00082 0.342
CLV_PCSK_KEX2_1 69 71 PF00082 0.492
CLV_PCSK_PC1ET2_1 178 180 PF00082 0.514
CLV_PCSK_PC1ET2_1 216 218 PF00082 0.555
CLV_PCSK_PC1ET2_1 258 260 PF00082 0.599
CLV_PCSK_PC1ET2_1 336 338 PF00082 0.583
CLV_PCSK_PC1ET2_1 377 379 PF00082 0.543
CLV_PCSK_PC1ET2_1 59 61 PF00082 0.347
CLV_PCSK_PC7_1 175 181 PF00082 0.572
CLV_PCSK_PC7_1 185 191 PF00082 0.552
CLV_PCSK_PC7_1 210 216 PF00082 0.614
CLV_PCSK_PC7_1 65 71 PF00082 0.607
CLV_PCSK_SKI1_1 108 112 PF00082 0.655
CLV_PCSK_SKI1_1 200 204 PF00082 0.611
CLV_PCSK_SKI1_1 210 214 PF00082 0.614
CLV_PCSK_SKI1_1 416 420 PF00082 0.557
CLV_PCSK_SKI1_1 65 69 PF00082 0.627
CLV_Separin_Metazoa 211 215 PF03568 0.533
DEG_Nend_UBRbox_2 1 3 PF02207 0.646
DOC_CYCLIN_RxL_1 22 35 PF00134 0.323
DOC_USP7_MATH_1 101 105 PF00917 0.548
DOC_USP7_MATH_1 418 422 PF00917 0.538
DOC_USP7_MATH_1 84 88 PF00917 0.674
DOC_USP7_MATH_1 91 95 PF00917 0.628
DOC_USP7_UBL2_3 225 229 PF12436 0.561
DOC_WW_Pin1_4 123 128 PF00397 0.734
DOC_WW_Pin1_4 85 90 PF00397 0.634
LIG_14-3-3_CanoR_1 108 116 PF00244 0.647
LIG_14-3-3_CanoR_1 137 145 PF00244 0.682
LIG_14-3-3_CanoR_1 365 372 PF00244 0.670
LIG_Actin_WH2_2 401 418 PF00022 0.536
LIG_APCC_ABBA_1 30 35 PF00400 0.323
LIG_FHA_1 367 373 PF00498 0.627
LIG_FHA_1 399 405 PF00498 0.530
LIG_FHA_1 422 428 PF00498 0.684
LIG_FHA_2 142 148 PF00498 0.658
LIG_FHA_2 366 372 PF00498 0.653
LIG_FHA_2 51 57 PF00498 0.440
LIG_FHA_2 66 72 PF00498 0.610
LIG_LIR_Gen_1 234 242 PF02991 0.625
LIG_LIR_Gen_1 5 12 PF02991 0.323
LIG_LIR_Nem_3 118 123 PF02991 0.560
LIG_LIR_Nem_3 133 139 PF02991 0.766
LIG_LIR_Nem_3 234 239 PF02991 0.573
LIG_LIR_Nem_3 41 47 PF02991 0.324
LIG_LIR_Nem_3 5 10 PF02991 0.323
LIG_PCNA_PIPBox_1 244 253 PF02747 0.520
LIG_Pex14_2 145 149 PF04695 0.534
LIG_RPA_C_Fungi 261 273 PF08784 0.620
LIG_SH2_CRK 51 55 PF00017 0.336
LIG_SH2_CRK 7 11 PF00017 0.336
LIG_SH2_NCK_1 236 240 PF00017 0.542
LIG_SH2_SRC 236 239 PF00017 0.605
LIG_SH2_STAP1 169 173 PF00017 0.521
LIG_SH2_STAP1 63 67 PF00017 0.478
LIG_SH2_STAT5 7 10 PF00017 0.418
LIG_SH3_3 83 89 PF00018 0.657
LIG_TRAF2_1 330 333 PF00917 0.633
LIG_TRAF2_1 338 341 PF00917 0.552
LIG_TRAF2_1 361 364 PF00917 0.617
MOD_CK1_1 126 132 PF00069 0.743
MOD_CK1_1 141 147 PF00069 0.646
MOD_CK1_1 421 427 PF00069 0.666
MOD_CK2_1 141 147 PF00069 0.586
MOD_CK2_1 365 371 PF00069 0.687
MOD_GlcNHglycan 128 131 PF01048 0.665
MOD_GlcNHglycan 391 397 PF01048 0.647
MOD_GlcNHglycan 420 423 PF01048 0.549
MOD_GlcNHglycan 60 63 PF01048 0.436
MOD_N-GLC_1 365 370 PF02516 0.661
MOD_NEK2_1 10 15 PF00069 0.418
MOD_PIKK_1 253 259 PF00454 0.574
MOD_PKA_1 398 404 PF00069 0.532
MOD_PKA_2 282 288 PF00069 0.637
MOD_PKA_2 366 372 PF00069 0.671
MOD_PKA_2 398 404 PF00069 0.525
MOD_Plk_1 392 398 PF00069 0.645
MOD_Plk_4 5 11 PF00069 0.418
MOD_ProDKin_1 123 129 PF00069 0.737
MOD_ProDKin_1 85 91 PF00069 0.636
MOD_SUMO_for_1 165 168 PF00179 0.604
MOD_SUMO_for_1 324 327 PF00179 0.632
MOD_SUMO_for_1 410 413 PF00179 0.622
MOD_SUMO_rev_2 218 227 PF00179 0.590
MOD_SUMO_rev_2 299 308 PF00179 0.510
MOD_SUMO_rev_2 327 335 PF00179 0.570
MOD_SUMO_rev_2 402 410 PF00179 0.576
MOD_SUMO_rev_2 428 432 PF00179 0.643
TRG_DiLeu_BaEn_4 263 269 PF01217 0.569
TRG_DiLeu_BaEn_4 339 345 PF01217 0.627
TRG_ENDOCYTIC_2 236 239 PF00928 0.511
TRG_ENDOCYTIC_2 51 54 PF00928 0.323
TRG_ENDOCYTIC_2 6 9 PF00928 0.337
TRG_ER_diArg_1 156 158 PF00400 0.652
TRG_ER_diArg_1 189 191 PF00400 0.537
TRG_ER_diArg_1 213 215 PF00400 0.534
TRG_ER_diArg_1 265 267 PF00400 0.494
TRG_ER_diArg_1 301 303 PF00400 0.603
TRG_ER_diArg_1 376 379 PF00400 0.676
TRG_ER_diArg_1 387 389 PF00400 0.528
TRG_ER_diArg_1 397 399 PF00400 0.488
TRG_NLS_MonoCore_2 104 109 PF00514 0.745
TRG_Pf-PMV_PEXEL_1 249 253 PF00026 0.569
TRG_Pf-PMV_PEXEL_1 259 263 PF00026 0.472
TRG_Pf-PMV_PEXEL_1 266 270 PF00026 0.442
TRG_Pf-PMV_PEXEL_1 342 347 PF00026 0.620
TRG_Pf-PMV_PEXEL_1 378 382 PF00026 0.527

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I0G8 Leptomonas seymouri 71% 100%
A0A0S4IRH8 Bodo saltans 44% 97%
A0A0S4JH45 Bodo saltans 25% 100%
A0A1X0P7B2 Trypanosomatidae 50% 97%
A0A3Q8IA51 Leishmania donovani 100% 100%
A0A3R7MIW9 Trypanosoma rangeli 51% 97%
A4H9W5 Leishmania braziliensis 90% 100%
D0A0C8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 49% 98%
E9ARV9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 97% 100%
Q4QDL3 Leishmania major 98% 100%
V5BWX2 Trypanosoma cruzi 51% 97%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS