LeishMANIAdb
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Putative peroxin 13

Quick info Annotations Function or PPIs Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative peroxin 13
Gene product:
peroxin 13 - putative
Species:
Leishmania infantum
UniProt:
E9AGQ9_LEIIN
TriTrypDb:
LINF_190005500
Length:
427

Annotations

Annotations by Jardim et al.

Glycosome membrane, peroxin 13 PEX13

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005778 peroxisomal membrane 6 1
GO:0005794 Golgi apparatus 5 1
GO:0016020 membrane 2 2
GO:0031090 organelle membrane 3 1
GO:0031903 microbody membrane 5 1
GO:0042579 microbody 5 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0046860 glycosome membrane 7 1
GO:0098588 bounding membrane of organelle 4 1
GO:0110165 cellular anatomical entity 1 2

Abundance

Amastigote (protein)
Source Evidence on protein Close homologs
Pescher et al. (upgregulation) no yes: 0
Promastigote and amastigote
Source Evidence on protein Close homologs
Lahav et al.
- mRNA
- Protein

Expansion

Sequence features

E9AGQ9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGQ9

Function

Biological processes
Term Name Level Count
GO:0006810 transport 3 1
GO:0006996 organelle organization 4 1
GO:0007031 peroxisome organization 5 1
GO:0009987 cellular process 1 1
GO:0015919 peroxisomal membrane transport 5 1
GO:0016043 cellular component organization 3 1
GO:0043574 peroxisomal transport 4 1
GO:0046907 intracellular transport 3 1
GO:0051179 localization 1 1
GO:0051234 establishment of localization 2 1
GO:0051641 cellular localization 2 1
GO:0051649 establishment of localization in cell 3 1
GO:0071840 cellular component organization or biogenesis 2 1
Could not find GO molecular_function term for this entry.

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 86 90 PF00656 0.374
CLV_NRD_NRD_1 135 137 PF00675 0.590
CLV_NRD_NRD_1 282 284 PF00675 0.413
CLV_NRD_NRD_1 356 358 PF00675 0.305
CLV_NRD_NRD_1 409 411 PF00675 0.194
CLV_PCSK_FUR_1 133 137 PF00082 0.519
CLV_PCSK_KEX2_1 135 137 PF00082 0.590
CLV_PCSK_KEX2_1 282 284 PF00082 0.403
CLV_PCSK_KEX2_1 356 358 PF00082 0.264
CLV_PCSK_KEX2_1 409 411 PF00082 0.220
DEG_APCC_DBOX_1 252 260 PF00400 0.234
DEG_Nend_Nbox_1 1 3 PF02207 0.328
DOC_MAPK_gen_1 156 166 PF00069 0.337
DOC_MAPK_gen_1 251 259 PF00069 0.181
DOC_MAPK_MEF2A_6 253 261 PF00069 0.203
DOC_PP1_RVXF_1 372 378 PF00149 0.326
DOC_USP7_MATH_1 370 374 PF00917 0.405
DOC_USP7_MATH_1 389 393 PF00917 0.453
DOC_USP7_MATH_1 69 73 PF00917 0.363
DOC_WW_Pin1_4 111 116 PF00397 0.473
DOC_WW_Pin1_4 126 131 PF00397 0.406
DOC_WW_Pin1_4 285 290 PF00397 0.675
LIG_14-3-3_CanoR_1 283 289 PF00244 0.594
LIG_14-3-3_CanoR_1 308 316 PF00244 0.655
LIG_14-3-3_CanoR_1 374 378 PF00244 0.326
LIG_Actin_WH2_2 166 181 PF00022 0.309
LIG_BIR_III_4 292 296 PF00653 0.605
LIG_eIF4E_1 44 50 PF01652 0.383
LIG_FHA_1 169 175 PF00498 0.292
LIG_FHA_1 226 232 PF00498 0.429
LIG_FHA_2 315 321 PF00498 0.647
LIG_FHA_2 324 330 PF00498 0.623
LIG_GBD_Chelix_1 166 174 PF00786 0.636
LIG_IBAR_NPY_1 68 70 PF08397 0.346
LIG_LIR_Apic_2 364 368 PF02991 0.354
LIG_LIR_Gen_1 415 424 PF02991 0.542
LIG_LIR_Nem_3 291 297 PF02991 0.554
LIG_LIR_Nem_3 415 420 PF02991 0.520
LIG_PDZ_Class_1 422 427 PF00595 0.528
LIG_Pex14_1 331 335 PF04695 0.635
LIG_Pex14_2 185 189 PF04695 0.247
LIG_SH2_CRK 294 298 PF00017 0.556
LIG_SH2_CRK 365 369 PF00017 0.393
LIG_SH2_SRC 388 391 PF00017 0.418
LIG_SH2_STAP1 193 197 PF00017 0.238
LIG_SH2_STAP1 303 307 PF00017 0.656
LIG_SH2_STAP1 363 367 PF00017 0.438
LIG_SH2_STAP1 404 408 PF00017 0.326
LIG_SH2_STAT3 363 366 PF00017 0.460
LIG_TRAF2_1 129 132 PF00917 0.398
LIG_WRC_WIRS_1 61 66 PF05994 0.594
MOD_CDK_SPxxK_3 126 133 PF00069 0.505
MOD_CK1_1 306 312 PF00069 0.603
MOD_CK1_1 314 320 PF00069 0.586
MOD_CK1_1 350 356 PF00069 0.360
MOD_CK1_1 373 379 PF00069 0.302
MOD_CK1_1 403 409 PF00069 0.196
MOD_CK1_1 74 80 PF00069 0.509
MOD_CK1_1 83 89 PF00069 0.458
MOD_CK1_1 98 104 PF00069 0.460
MOD_CK2_1 126 132 PF00069 0.456
MOD_CK2_1 177 183 PF00069 0.293
MOD_CK2_1 285 291 PF00069 0.476
MOD_CK2_1 296 302 PF00069 0.481
MOD_CK2_1 307 313 PF00069 0.556
MOD_CK2_1 323 329 PF00069 0.400
MOD_CK2_1 389 395 PF00069 0.315
MOD_CMANNOS 252 255 PF00535 0.343
MOD_GlcNHglycan 179 182 PF01048 0.371
MOD_GlcNHglycan 18 21 PF01048 0.566
MOD_GlcNHglycan 235 238 PF01048 0.499
MOD_GlcNHglycan 245 248 PF01048 0.440
MOD_GlcNHglycan 349 352 PF01048 0.561
MOD_GlcNHglycan 46 49 PF01048 0.511
MOD_GlcNHglycan 57 60 PF01048 0.504
MOD_GSK3_1 243 250 PF00069 0.560
MOD_GSK3_1 303 310 PF00069 0.529
MOD_GSK3_1 51 58 PF00069 0.528
MOD_N-GLC_1 126 131 PF02516 0.530
MOD_N-GLC_1 74 79 PF02516 0.476
MOD_NEK2_1 21 26 PF00069 0.463
MOD_NEK2_1 215 220 PF00069 0.595
MOD_NEK2_1 34 39 PF00069 0.409
MOD_NEK2_1 50 55 PF00069 0.543
MOD_NEK2_1 96 101 PF00069 0.652
MOD_NEK2_2 22 27 PF00069 0.389
MOD_NEK2_2 303 308 PF00069 0.601
MOD_PIKK_1 225 231 PF00454 0.483
MOD_PIKK_1 296 302 PF00454 0.465
MOD_PIKK_1 341 347 PF00454 0.496
MOD_PIKK_1 88 94 PF00454 0.698
MOD_PKA_2 284 290 PF00069 0.485
MOD_PKA_2 307 313 PF00069 0.567
MOD_PKA_2 314 320 PF00069 0.621
MOD_PKA_2 347 353 PF00069 0.669
MOD_PKA_2 373 379 PF00069 0.138
MOD_Plk_1 303 309 PF00069 0.530
MOD_Plk_1 323 329 PF00069 0.516
MOD_Plk_1 74 80 PF00069 0.476
MOD_Plk_2-3 323 329 PF00069 0.475
MOD_Plk_4 188 194 PF00069 0.313
MOD_Plk_4 22 28 PF00069 0.403
MOD_Plk_4 34 40 PF00069 0.405
MOD_ProDKin_1 111 117 PF00069 0.624
MOD_ProDKin_1 126 132 PF00069 0.527
MOD_ProDKin_1 285 291 PF00069 0.623
TRG_ENDOCYTIC_2 192 195 PF00928 0.290
TRG_ENDOCYTIC_2 294 297 PF00928 0.460
TRG_ENDOCYTIC_2 359 362 PF00928 0.318
TRG_ER_diArg_1 133 136 PF00400 0.405
TRG_ER_diArg_1 282 285 PF00400 0.587
TRG_ER_diArg_1 356 358 PF00400 0.451
TRG_NES_CRM1_1 165 176 PF08389 0.362
TRG_Pf-PMV_PEXEL_1 145 150 PF00026 0.527
TRG_PTS1 424 427 PF00515 0.443

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1P9X6 Leptomonas seymouri 69% 100%
A0A0S4J170 Bodo saltans 25% 94%
A0A1X0P6F7 Trypanosomatidae 35% 100%
A0A3S7WV91 Leishmania donovani 100% 100%
A0A422NCY3 Trypanosoma rangeli 32% 100%
A4H9W4 Leishmania braziliensis 79% 100%
D0A0C7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
E9ARV8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
Q4QDL4 Leishmania major 90% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS